Pyrrolopyridine Inhibitors of Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MK-2)
Anderson, David R, Meyers, Marvin J, Vernier, William F, Mahoney, Matthew W, Kurumbail, Ravi G, Caspers, Nicole, Poda, Gennadiy I, Schindler, John F, Reitz, David B, Mourey, Robert J
Published in Journal of medicinal chemistry (31.05.2007)
Published in Journal of medicinal chemistry (31.05.2007)
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Discovery of (3S,3aR)-2-(3-Chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2H-benzo[g]indazole-7-carboxylic Acid (PF-3882845), an Orally Efficacious Mineralocorticoid Receptor (MR) Antagonist for Hypertension and Nephropathy
Meyers, Marvin J, Arhancet, Graciela B, Hockerman, Susan L, Chen, Xiangyang, Long, Scott A, Mahoney, Matthew W, Rico, Joseph R, Garland, Danny J, Blinn, James. R, Collins, Joe T, Yang, Shengtian, Huang, Horng-Chih, McGee, Kevin F, Wendling, Jay M, Dietz, Jessica D, Payne, Maria A, Homer, Bruce L, Heron, Marcia I, Reitz, David B, Hu, Xiao
Published in Journal of medicinal chemistry (26.08.2010)
Published in Journal of medicinal chemistry (26.08.2010)
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Novel tetrahydro-β-carboline-1-carboxylic acids as inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2)
Trujillo, John I., Meyers, Marvin J., Anderson, David R., Hegde, Shridhar, Mahoney, Matthew W., Vernier, William F., Buchler, Ingrid P., Wu, Kun K., Yang, Syaluan, Hartmann, Susan J., Reitz, David B.
Published in Bioorganic & medicinal chemistry letters (15.08.2007)
Published in Bioorganic & medicinal chemistry letters (15.08.2007)
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A Highly Enantioselective Benzothiepine Synthesis
Wang, Ching-Cheng, Li, James J, Huang, Horng-Chih, Lee, Len F, Reitz, David B
Published in Journal of organic chemistry (05.05.2000)
Published in Journal of organic chemistry (05.05.2000)
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Diarylspiro[2.4]heptenes as Orally Active, Highly Selective Cyclooxygenase-2 Inhibitors: Synthesis and Structure−Activity Relationships
Huang, Horng-Chih, Li, James J, Garland, Danny J, Chamberlain, Timothy S, Reinhard, Emily J, Manning, Robert E, Seibert, Karen, Koboldt, Carol M, Gregory, Susan A, Anderson, Gary D, Veenhuizen, Amy W, Zhang, Yan, Perkins, William E, Burton, Earl G, Cogburn, J. Nita, Isakson, Peter C, Reitz, David B
Published in Journal of medicinal chemistry (05.01.1996)
Published in Journal of medicinal chemistry (05.01.1996)
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Design, synthesis, and biological evaluation of pyrazinones containing novel P1 needles as inhibitors of TF/VIIa
Trujillo, John I., Huang, Horng-Chih, Neumann, William L., Mahoney, Matthew W., Long, Scott, Huang, Wei, Garland, Danny J., Kusturin, Carrie, Abbas, Zaheer, South, Michael S., Reitz, David B.
Published in Bioorganic & medicinal chemistry letters (15.08.2007)
Published in Bioorganic & medicinal chemistry letters (15.08.2007)
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A novel class of apical sodium co-dependent bile acid transporter inhibitors: The 1,2-benzothiazepines
TOLLEFSON, Michael B, KOLODZIEJ, Stephen A, FLETCHER, Theresa R, VERNIER, William F, BEAUDRY, Judith A, KELLER, Bradley T, REITZ, David B
Published in Bioorganic & medicinal chemistry letters (03.11.2003)
Published in Bioorganic & medicinal chemistry letters (03.11.2003)
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Journal Article
Novel Terphenyls as Selective Cyclooxygenase-2 Inhibitors and Orally Active Anti-inflammatory Agents
Li, James J, Norton, Monica B, Reinhard, Emily J, Anderson, Gary D, Gregory, Susan A, Isakson, Peter C, Koboldt, Carol M, Masferrer, Jaime L, Perkins, William E, Seibert, Karen, Zhang, Yan, Zweifel, Ben S, Reitz, David B
Published in Journal of medicinal chemistry (26.04.1996)
Published in Journal of medicinal chemistry (26.04.1996)
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Journal Article
Discovery of (3 S ,3a R )-2-(3-Chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2 H -benzo[ g ]indazole-7-carboxylic Acid (PF-3882845), an Orally Efficacious Mineralocorticoid Receptor (MR) Antagonist for Hypertension and Nephropathy
Meyers, Marvin J., Arhancet, Graciela B., Hockerman, Susan L., Chen, Xiangyang, Long, Scott A., Mahoney, Matthew W., Rico, Joseph R., Garland, Danny J., Blinn, James. R., Collins, Joe T., Yang, Shengtian, Huang, Horng-Chih, McGee, Kevin F., Wendling, Jay M., Dietz, Jessica D., Payne, Maria A., Homer, Bruce L., Heron, Marcia I., Reitz, David B., Hu, Xiao
Published in Journal of medicinal chemistry (26.08.2010)
Published in Journal of medicinal chemistry (26.08.2010)
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Journal Article
Synthesis and structure-activity relationships of nonpeptide, potent triazolone-based angiotensin II receptor antagonists
Huang, Horng Chih, Reitz, David B, Chamberlain, Timothy S, Olins, Gillian M, Corpus, Valerie M, McMahon, Ellen G, Palomo, Maria A, Koepke, John P, Smits, Glenn J
Published in Journal of medicinal chemistry (23.07.1993)
Published in Journal of medicinal chemistry (23.07.1993)
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Journal Article
Discovery of Potent, Nonsystemic Apical Sodium-Codependent Bile Acid Transporter Inhibitors (Part 1)
Tremont, Samuel J, Lee, Len F, Huang, Horng-Chih, Keller, Bradley T, Banerjee, Shyamal C, Both, Scott R, Carpenter, Andrew J, Wang, Ching-Cheng, Garland, Danny J, Huang, Wei, Jones, Claude, Koeller, Kevin J, Kolodziej, Steve A, Li, James, Manning, Robert E, Mahoney, Matthew W, Miller, Raymond E, Mischke, Deborah A, Rath, Nigam P, Fletcher, Theresa, Reinhard, Emily J, Tollefson, Michael B, Vernier, William F, Wagner, Grace M, Rapp, Steve R, Beaudry, Judy, Glenn, Kevin, Regina, Karen, Schuh, Joe R, Smith, Mark E, Trivedi, Jay S, Reitz, David B
Published in Journal of medicinal chemistry (08.09.2005)
Published in Journal of medicinal chemistry (08.09.2005)
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Corrigendum to “Novel tetrahydro-β-carboline-1-carboxylic acids as inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2)” [Bioorg. Med. Chem. Lett. 17 (2007) 4657–4663]
Trujillo, John I., Meyers, Marvin J., Anderson, David R., Hegde, Shridhar, Mahoney, Matthew W., Vernier, William F., Buchler, Ingrid P., Wu, Kun K., Yang, Syaulan, Hartmann, Susan J., Reitz, David B.
Published in Bioorganic & medicinal chemistry letters (15.04.2009)
Published in Bioorganic & medicinal chemistry letters (15.04.2009)
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Journal Article
Discovery of Potent, Nonsystemic Apical Sodium-Codependent Bile Acid Transporter Inhibitors (Part 2)
Huang, Horng-Chih, Tremont, Samuel J, Lee, Len F, Keller, Bradley T, Carpenter, Andrew J, Wang, Ching-Cheng, Banerjee, Shyamal C, Both, Scott R, Fletcher, Theresa, Garland, Danny J, Huang, Wei, Jones, Claude, Koeller, Kevin J, Kolodziej, Steve A, Li, James, Manning, Robert E, Mahoney, Matthew W, Miller, Raymond E, Mischke, Deborah A, Rath, Nigam P, Reinhard, Emily J, Tollefson, Michael B, Vernier, William F, Wagner, Grace M, Rapp, Steve R, Beaudry, Judy, Glenn, Kevin, Regina, Karen, Schuh, Joe R, Smith, Mark E, Trivedi, Jay S, Reitz, David B
Published in Journal of medicinal chemistry (08.09.2005)
Published in Journal of medicinal chemistry (08.09.2005)
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