Small-molecule probes targeting the viral PPxY-host Nedd4 interface block egress of a broad range of RNA viruses
Han, Ziying, Lu, Jianhong, Liu, Yuliang, Davis, Benjamin, Lee, Michael S, Olson, Mark A, Ruthel, Gordon, Freedman, Bruce D, Schnell, Matthias J, Wrobel, Jay E, Reitz, Allen B, Harty, Ronald N
Published in Journal of virology (01.07.2014)
Published in Journal of virology (01.07.2014)
Get full text
Journal Article
Calcium Regulation of Hemorrhagic Fever Virus Budding: Mechanistic Implications for Host-Oriented Therapeutic Intervention
Han, Ziying, Madara, Jonathan J, Herbert, Andrew, Prugar, Laura I, Ruthel, Gordon, Lu, Jianhong, Liu, Yuliang, Liu, Wenbo, Liu, Xiaohong, Wrobel, Jay E, Reitz, Allen B, Dye, John M, Harty, Ronald N, Freedman, Bruce D
Published in PLoS pathogens (01.10.2015)
Published in PLoS pathogens (01.10.2015)
Get full text
Journal Article
Biophysical Screens Identify Fragments That Bind to the Viral DNA-Binding Proteins EBNA1 and LANA
Messick, Troy E, Tolvinski, Lois, Zartler, Edward R, Moberg, Anna, Frostell, Åsa, Smith, Garry R, Reitz, Allen B, Lieberman, Paul M
Published in Molecules (Basel, Switzerland) (10.04.2020)
Published in Molecules (Basel, Switzerland) (10.04.2020)
Get full text
Journal Article
Cypin: A novel target for traumatic brain injury
Swiatkowski, Przemyslaw, Sewell, Emily, Sweet, Eric S., Dickson, Samantha, Swanson, Rachel A., McEwan, Sara A., Cuccolo, Nicholas, McDonnell, Mark E., Patel, Mihir V., Varghese, Nevin, Morrison, Barclay, Reitz, Allen B., Meaney, David F., Firestein, Bonnie L.
Published in Neurobiology of disease (01.11.2018)
Published in Neurobiology of disease (01.11.2018)
Get full text
Journal Article
Advancement of the 5-Amino-1-(Carbamoylmethyl)-1H-1,2,3-Triazole-4-Carboxamide Scaffold to Disarm the Bacterial SOS Response
Selwood, Trevor, Larsen, Brian J, Mo, Charlie Y, Culyba, Matthew J, Hostetler, Zachary M, Kohli, Rahul M, Reitz, Allen B, Baugh, Simon D P
Published in Frontiers in microbiology (18.12.2018)
Published in Frontiers in microbiology (18.12.2018)
Get full text
Journal Article
Antiretroviral Drug Discovery Targeting the HIV-1 Nef Virulence Factor
Emert-Sedlak, Lori A, Shi, Haibin, Tice, Colin M, Chen, Li, Alvarado, John J, Shu, Sherry T, Du, Shoucheng, Thomas, Catherine E, Wrobel, Jay E, Reitz, Allen B, Smithgall, Thomas E
Published in Viruses (01.09.2022)
Published in Viruses (01.09.2022)
Get full text
Journal Article
Riluzole prodrugs for melanoma and ALS: Design, synthesis, and in vitro metabolic profiling
McDonnell, Mark E., Vera, Matthew D., Blass, Benjamin E., Pelletier, Jeffrey C., King, Richard C., Fernandez-Metzler, Carmen, Smith, Garry R., Wrobel, Jay, Chen, Suzie, Wall, Brian A., Reitz, Allen B.
Published in Bioorganic & medicinal chemistry (15.09.2012)
Published in Bioorganic & medicinal chemistry (15.09.2012)
Get full text
Journal Article
Current nervous system related drug targets for the treatment of amyotrophic lateral sclerosis
Pawlyk, Aaron C, Cassel, Joel A, Reitz, Allen B
Published in Current pharmaceutical design (01.06.2010)
Published in Current pharmaceutical design (01.06.2010)
Get more information
Journal Article
Preparation of 3-spirocyclic indolin-2-ones as ligands for the ORL-1 receptor
Bignan, Gilles C., Battista, Kathleen, Connolly, Peter J., Orsini, Michael J., Liu, Jingchun, Middleton, Steven A., Reitz, Allen B.
Published in Bioorganic & medicinal chemistry letters (15.11.2005)
Published in Bioorganic & medicinal chemistry letters (15.11.2005)
Get full text
Journal Article
Development of a Novel Nonradiometric Assay for Nucleic Acid Binding to TDP-43 Suitable for High-Throughput Screening Using AlphaScreen® Technology
Cassel, Joel A., Blass, Benjamin E., Reitz, Allen B., Pawlyk, Aaron C.
Published in Journal of biomolecular screening (01.10.2010)
Published in Journal of biomolecular screening (01.10.2010)
Get full text
Journal Article
Macrocyclic BACE inhibitors: Optimization of a micromolar hit to nanomolar leads
Huang, Yifang, Strobel, Eric D., Ho, Chih Y., Reynolds, Charles H., Conway, Kelly A., Piesvaux, Jennifer A., Brenneman, Douglas E., Yohrling, George J., Moore Arnold, H., Rosenthal, Daniel, Alexander, Richard S., Tounge, Brett A., Mercken, Marc, Vandermeeren, Marc, Parker, Michael H., Reitz, Allen B., Baxter, Ellen W.
Published in Bioorganic & medicinal chemistry letters (15.05.2010)
Published in Bioorganic & medicinal chemistry letters (15.05.2010)
Get full text
Journal Article
PROTAC-mediated degradation of HIV-1 Nef efficiently restores cell-surface CD4 and MHC-I expression and blocks HIV-1 replication
Emert-Sedlak, Lori A., Tice, Colin M., Shi, Haibin, Alvarado, John J., Shu, Sherry T., Reitz, Allen B., Smithgall, Thomas E.
Published in Cell chemical biology (18.04.2024)
Published in Cell chemical biology (18.04.2024)
Get full text
Journal Article
Structure-based design of small-molecule inhibitors of EBNA1 DNA binding blocks Epstein-Barr virus latent infection and tumor growth
Messick, Troy E, Smith, Garry R, Soldan, Samantha S, McDonnell, Mark E, Deakyne, Julianna S, Malecka, Kimberly A, Tolvinski, Lois, van den Heuvel, A Pieter J, Gu, Bai-Wei, Cassel, Joel A, Tran, Donna H, Wassermann, Benjamin R, Zhang, Yan, Velvadapu, Venkata, Zartler, Edward R, Busson, Pierre, Reitz, Allen B, Lieberman, Paul M
Published in Science translational medicine (06.03.2019)
Published in Science translational medicine (06.03.2019)
Get more information
Journal Article
Inhibitors of the protein disulfide isomerase family for the treatment of multiple myeloma
Robinson, Reeder M, Reyes, Leticia, Duncan, Ravyn M, Bian, Haiyan, Reitz, Allen B, Manevich, Yefim, McClure, Jesse J, Champion, Matthew M, Chou, C James, Sharik, Meahgen E, Chesi, Marta, Bergsagel, P Leif, Dolloff, Nathan G
Published in Leukemia (01.04.2019)
Published in Leukemia (01.04.2019)
Get full text
Journal Article
Troriluzole inhibits methamphetamine place preference in rats and normalizes methamphetamine-evoked glutamate carboxypeptidase II (GCPII) protein levels in the mesolimbic pathway
Wiah, Sonita, Roper, Abigail, Zhao, Pingwei, Shekarabi, Aryan, Watson, Mia N., Farkas, Daniel J., Potula, Raghava, Reitz, Allen B., Rawls, Scott M.
Published in Drug and alcohol dependence (01.01.2023)
Published in Drug and alcohol dependence (01.01.2023)
Get full text
Journal Article
Non-NAD-like PARP-1 inhibitors in prostate cancer treatment
Karpova, Yaroslava, Wu, Chao, Divan, Ali, McDonnell, Mark E., Hewlett, Elizabeth, Makhov, Peter, Gordon, John, Ye, Min, Reitz, Allen B., Childers, Wayne E., Skorski, Tomasz, Kolenko, Vladimir, Tulin, Alexei V.
Published in Biochemical pharmacology (01.09.2019)
Published in Biochemical pharmacology (01.09.2019)
Get full text
Journal Article