Dependence on the Pyrimidine Biosynthetic Enzyme DHODH Is a Synthetic Lethal Vulnerability in Mutant KRAS-Driven Cancers
Koundinya, Malvika, Sudhalter, Judith, Courjaud, Albane, Lionne, Bruno, Touyer, Gaetan, Bonnet, Luc, Menguy, Isabelle, Schreiber, Isabelle, Perrault, Christelle, Vougier, Stephanie, Benhamou, Brigitte, Zhang, Bailin, He, Timothy, Gao, Qiang, Gee, Patricia, Simard, Daniel, Castaldi, M. Paola, Tomlinson, Ronald, Reiling, Stephan, Barrague, Matthieu, Newcombe, Richard, Cao, Hui, Wang, Yanjun, Sun, Fangxian, Murtie, Joshua, Munson, Mark, Yang, Eric, Harper, David, Bouaboula, Monsif, Pollard, Jack, Grepin, Claudine, Garcia-Echeverria, Carlos, Cheng, Hong, Adrian, Francisco, Winter, Christopher, Licht, Stuart, Cornella-Taracido, Ivan, Arrebola, Rosalia, Morris, Aaron
Published in Cell chemical biology (21.06.2018)
Published in Cell chemical biology (21.06.2018)
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Journal Article
Molecular Similarity Searching Using Atom Environments, Information-Based Feature Selection, and a Naïve Bayesian Classifier
Bender, Andreas, Mussa, Hamse Y, Glen, Robert C, Reiling, Stephan
Published in Journal of Chemical Information and Computer Sciences (01.01.2004)
Published in Journal of Chemical Information and Computer Sciences (01.01.2004)
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Journal Article
A NMDA-receptor calcium influx assay sensitive to stimulation by glutamate and glycine/D-serine
Guo, Hongqiu, Camargo, L. Miguel, Yeboah, Fred, Digan, Mary Ellen, Niu, Honglin, Pan, Yue, Reiling, Stephan, Soler-Llavina, Gilberto, Weihofen, Wilhelm A., Wang, Hao-Ran, Shanker, Y. Gopi, Stams, Travis, Bill, Anke
Published in Scientific reports (14.09.2017)
Published in Scientific reports (14.09.2017)
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Journal Article
Screenit: Visual Analysis of Cellular Screens
Dinkla, Kasper, Strobelt, Hendrik, Genest, Bryan, Reiling, Stephan, Borowsky, Mark, Pfister, Hanspeter
Published in IEEE transactions on visualization and computer graphics (01.01.2017)
Published in IEEE transactions on visualization and computer graphics (01.01.2017)
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Journal Article
Amelioration of PXR-mediated CYP3A4 induction by mGluR2 modulators
Vaz, Roy J., Li, Yi, Chellaraj, Vinolia, Reiling, Stephan, Kuntzweiler, Theresa, Yang, Donglai, Shen, Hong, Batchelor, Joseph D., Zhang, Ying, Chen, Xin, McLean, Larry R., Kosley, Raymond
Published in Bioorganic & medicinal chemistry letters (15.10.2018)
Published in Bioorganic & medicinal chemistry letters (15.10.2018)
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Journal Article
Prediction of the 3D Structure and Dynamics of Human DP G-Protein Coupled Receptor Bound to an Agonist and an Antagonist
Li, Youyong, Zhu, Fangqiang, Vaidehi, Nagarajan, Goddard, William A, Sheinerman, Felix, Reiling, Stephan, Morize, Isabelle, Mu, Lan, Harris, Keith, Ardati, Ali, Laoui, Abdelazize
Published in Journal of the American Chemical Society (05.09.2007)
Published in Journal of the American Chemical Society (05.09.2007)
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Journal Article
Discovery of covalent inhibitors for MIF tautomerase via cocrystal structures with phantom hits from virtual screening
McLean, Larry R., Zhang, Ying, Li, Hua, Li, Ziyu, Lukasczyk, Ulrike, Choi, Yong-Mi, Han, Zuoning, Prisco, Joy, Fordham, Jeremy, Tsay, Joseph T., Reiling, Stephan, Vaz, Roy J., Li, Yi
Published in Bioorganic & medicinal chemistry letters (01.12.2009)
Published in Bioorganic & medicinal chemistry letters (01.12.2009)
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Journal Article
Abstract 2201: The molecular signature of tumor cells that are sensitives to a new tight binder NAMPT inhibitor
Hilairet, Sandrine, Arigon, Jerome, Nardi, Frederico, Jegham, Samir, Peleraux, Annick, Cosnier, Sylvie, Floutard, Regine, Jbilo, Omar, August, Paul, Shomali, Maysoun, Autelitano, Francois, Arrebola, Rosalia, Reiling, Stephan, Pollard, Jack, Adrian, Francisco, Sager, Jason, Lengauer, Christoph, Dorsh, Marion, Garcia-Echeverria, Carlos, Bouaboula, Monsif
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Journal Article
Abstract 2243: Clonogenic 3D high throughput screening in mutant KRAS dependent cancer cells - a chemogenomic approach
Koundinya, Malvika, Sudhalter, Judith, Courjaud, Albane, Lionne, Bruno, Touyer, Gaetan, Bonnet, Luc, Menguy, Isabelle, Schreiber, Isabelle, Perrault, Christelle, Vougier, Stephanie, Benhamou, Brigitte, Simard, Daniel, Castaldi, Maria Paola, Tomlinson, Ronald, Reiling, Stephan, Cao, Hui, Harper, David, Bouaboula, Monsif, Pollard, Jack, Grepin, Claudine, Garcia-Echeverria, Carlos, Adrian, Francisco, Cornella-Taracido, Ivan, Arrebola, Rosalia, Morris, Aaron J.
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Journal Article
Abstract 3135: In vitro and in vivo synthetic lethal screens to identify novel targets in the context of PTEN deficiency
Zhang, Jing-xin, Murtie, Joshua, Iartchouk, Oleg, Cao, Hui, Shapiro, Gary, Li, Zhifang, Wang, Hongyun, Ding, Zhihu, Zhang, Yu-an, Light, Madelyn, Hoffman, Dietmar, Cindhuchao, May, Jani, Saurin, Newcombe, Richard, Bric-Furlong, Eva, Wu, Bin, Virone-Oddos, Angela, Reiling, Stephan, Theihaber, Joachim, Lengauer, Christoph, Pollard, Jack, Watters, James, Silver, Serena, Reddy, Venkat
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Journal Article
On the mechanism of microsomal prostaglandin E synthase type-2 - A theoretical study of endoperoxide reaction with MeS super(-)
Li, Yi, Angelastro, Michael, Shimshock, Stephen, Reiling, Stephan, Vaz, Roy J
Published in Bioorganic & medicinal chemistry letters (01.01.2010)
Published in Bioorganic & medicinal chemistry letters (01.01.2010)
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Journal Article
Abstract A226: Mechanism of action of iniparib: Stimulation of reactive oxygen species (ROS) production in an iniparib-sensitive breast cancer cell line
Licht, Stuart, Cao, Hui, Li, Zhifang, Zhang, Jingxin, Liu, Feng, Brittain, Scott, Shen, Junqing, Zhang, Bailin, Hopke, Joern, Newcombe, Rick, Reiling, Stephan, Pollard, Jack, Watters, James, Cheng, Hong, Reddy, Venkateshwar, Bergstrom, Donald A.
Published in Molecular cancer therapeutics (12.11.2011)
Published in Molecular cancer therapeutics (12.11.2011)
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Journal Article
Force field parameters for carbohydrates
Reiling, Stephan, Schlenkrich, Michael, Brickmann, Jürgen
Published in Journal of computational chemistry (01.03.1996)
Published in Journal of computational chemistry (01.03.1996)
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Journal Article
Theoretical Studies on the Pyridine−I2 Charge-Transfer Complex. 1. Ab-Initio Calculations on I2 and Pyridine−I2
Reiling, Stephan, Besnard, Marcel, Bopp, Philippe A
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (12.06.1997)
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (12.06.1997)
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Journal Article
A SUBSTITUTED PYRIMIDINE AS A PROSTAGLANDIN D2 RECEPTOR ANTAGONIST
REILING STEPHAN, HARRIS KEITH JOHN, AGUIAR JOACY C, POLI GREGORY B, STOKLOSA GREGORY T, ZHAO ZHICHENG, CHOI SLEDESKI YONG MI, SHUM PATRICK WAI KWOK
Year of Publication 21.01.2013
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Year of Publication 21.01.2013
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