Targeting key angiogenic pathways with a bispecific CrossMAb optimized for neovascular eye diseases
Regula, Jörg T, Lundh von Leithner, Peter, Foxton, Richard, Barathi, Veluchamy A, Cheung, Chui Ming Gemmy, Bo Tun, Sai Bo, Wey, Yeo Sia, Iwata, Daiju, Dostalek, Miroslav, Moelleken, Jörg, Stubenrauch, Kay G, Nogoceke, Everson, Widmer, Gabriella, Strassburger, Pamela, Koss, Michael J, Klein, Christian, Shima, David T, Hartmann, Guido
Published in EMBO molecular medicine (01.11.2016)
Published in EMBO molecular medicine (01.11.2016)
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Journal Article
Immunoglobulin domain crossover as a generic approach for the production of bispecific IgG antibodies
Schaefer, Wolfgang, Regula, Jörg T, Bähner, Monika, Schanzer, Jürgen, Croasdale, Rebecca, Dürr, Harald, Gassner, Christian, Georges, Guy, Kettenberger, Hubert, Imhof-Jung, Sabine, Schwaiger, Manfred, Stubenrauch, Kay G, Sustmann, Claudio, Thomas, Markus, Scheuer, Werner, Klein, Christian
Published in Proceedings of the National Academy of Sciences - PNAS (05.07.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (05.07.2011)
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Journal Article
Progress in overcoming the chain association issue in bispecific heterodimeric IgG antibodies
Klein, Christian, Sustmann, Claudio, Thomas, Markus, Stubenrauch, Kay, Croasdale, Rebecca, Schanzer, Jürgen, Brinkmann, Ulrich, Kettenberger, Hubert, Regula, Jörg T., Schaefer, Wolfgang
Published in mAbs (01.11.2012)
Published in mAbs (01.11.2012)
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Journal Article
A novel angiopoietin-2 selective fully human antibody with potent anti-tumoral and anti-angiogenic efficacy and superior side effect profile compared to Pan-Angiopoietin-1/-2 inhibitors
Thomas, Markus, Kienast, Yvonne, Scheuer, Werner, Bähner, Monika, Kaluza, Klaus, Gassner, Christian, Herting, Frank, Brinkmann, Ulrich, Seeber, Stefan, Kavlie, Anita, Welschof, Martin, Ries, Stefan, Weidner, K Michael, Regula, Jörg T, Klein, Christian
Published in PloS one (06.02.2013)
Published in PloS one (06.02.2013)
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Journal Article
Cell Type-Specific and Site Directed N-Glycosylation Pattern of FcγRIIIa
Zeck, Anne, Pohlentz, Gottfried, Schlothauer, Tilman, Peter-Katalinić, Jasna, Regula, Jörg Thomas
Published in Journal of proteome research (01.07.2011)
Published in Journal of proteome research (01.07.2011)
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Journal Article
Heavy and light chain pairing of bivalent quadroma and knobs-into-holes antibodies analyzed by UHR-ESI-QTOF mass spectrometry
Schaefer, Wolfgang, Völger, Hans R, Lorenz, Stefan, Imhof-Jung, Sabine, Regula, Jörg T, Klein, Christian, Mølhøj, Michael
Published in mAbs (01.01.2016)
Published in mAbs (01.01.2016)
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Journal Article
Low level sequence variant analysis of recombinant proteins: an optimized approach
Zeck, Anne, Regula, Jörg Thomas, Larraillet, Vincent, Mautz, Björn, Popp, Oliver, Göpfert, Ulrich, Wiegeshoff, Frank, Vollertsen, Ulrike E E, Gorr, Ingo H, Koll, Hans, Papadimitriou, Apollon
Published in PloS one (06.07.2012)
Published in PloS one (06.07.2012)
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Journal Article
DuoMab: a novel CrossMab-based IgG-derived antibody format for enhanced antibody-dependent cell-mediated cytotoxicity
Sustmann, Claudio, Dickopf, Steffen, Regula, Jörg T, Kettenberger, Hubert, Mølhøj, Michael, Gassner, Christian, Weininger, Diana, Fenn, Sebastian, Manigold, Tobias, Kling, Lothar, Künkele, Klaus-Peter, Schwaiger, Manfred, Bossenmaier, Birgit, Griese, Julia J, Hopfner, Karl-Peter, Graff-Meyer, Alexandra, Stahlberg, Henning, Ringler, Philippe, Lauer, Matthias E, Brinkmann, Ulrich, Schaefer, Wolfgang, Klein, Christian
Published in mAbs (17.11.2019)
Published in mAbs (17.11.2019)
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Journal Article
Targeting key angiogenic pathways with a bispecific CrossMAb optimized for neovascular eye diseases
Regula, Jörg T, Lundh von Leithner, Peter, Foxton, Richard, Barathi, Veluchamy A, Chui Ming, Gemmy Cheung, Tun, Sai Bo Bo, Wey, Yeo Sia, Iwata, Daiju, Dostalek, Miroslav, Moelleken, Jörg, Stubenrauch, Kay G, Nogoceke, Everson, Widmer, Gabriella, Strassburger, Pamela, Koss, Michael J, Klein, Christian, Shima, David T, Hartmann, Guido
Published in EMBO molecular medicine (01.05.2019)
Published in EMBO molecular medicine (01.05.2019)
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Journal Article
Targeting key angiogenic pathways with a bispecific CrossMAb optimized for neovascular eye diseases
Regula, Jörg T, Lundh von Leithner, Peter, Foxton, Richard, Barathi, Veluchamy A, Gemmy Cheung, Chui Ming, Bo Tun, Sai Bo, Wey, Yeo Sia, Iwata, Daiju, Dostalek, Miroslav, Moelleken, Jörg, Stubenrauch, Kay G, Nogoceke, Everson, Widmer, Gabriella, Strassburger, Pamela, Koss, Michael J, Klein, Christian, Shima, David T, Hartmann, Guido
Published in EMBO molecular medicine (01.07.2017)
Published in EMBO molecular medicine (01.07.2017)
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Journal Article
Nicalin and its binding partner Nomo are novel Nodal signaling antagonists
Haffner, Christof, Frauli, Mélanie, Topp, Stephanie, Irmler, Martin, Hofmann, Kay, Regula, Jörg T, Bally-Cuif, Laure, Haass, Christian
Published in The EMBO journal (04.08.2004)
Published in The EMBO journal (04.08.2004)
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Journal Article
DuoMab: a novel CrossMab-based IgG-derived antibody format for enhanced antibody-dependent cell-mediated cytotoxicity
Sustmann, Claudio, Dickopf, Steffen, Regula, Jörg T., Kettenberger, Hubert, Mølhøj, Michael, Gassner, Christian, Weininger, Diana, Fenn, Sebastian, Manigold, Tobias, Kling, Lothar, Künkele, Klaus-Peter, Schwaiger, Manfred, Bossenmaier, Birgit, Griese, Julia J., Hopfner, Karl-Peter, Graff-Meyer, Alexandra, Stahlberg, Henning, Ringler, Philippe, Lauer, Matthias E., Brinkmann, Ulrich, Schaefer, Wolfgang, Klein, Christian
Published in mAbs (17.11.2019)
Published in mAbs (17.11.2019)
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Journal Article
Differential Effects of Parkinson's Disease-associated Mutations on Stability and Folding of DJ-1
Görner, Karin, Holtorf, Eve, Odoy, Sabine, Nuscher, Brigitte, Yamamoto, Ayako, Regula, Jörg T., Beyer, Klaus, Haass, Christian, Kahle, Philipp J.
Published in The Journal of biological chemistry (20.02.2004)
Published in The Journal of biological chemistry (20.02.2004)
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Journal Article
Analysis of the major proteins secreted by the human opportunistic pathogen Aspergillus fumigatus under in vitro conditions
Schwienbacher, Monika, Weig, Michael, Thies, Svenja, Regula, Jörg T, Heesemann, Jürgen, Ebel, Frank
Published in Medical mycology (Oxford) (01.11.2005)
Published in Medical mycology (Oxford) (01.11.2005)
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Journal Article
The acidic, glutamine-rich Mpn474 protein of Mycoplasma pneumoniae is surface exposed and covers the complete cell
Hegermann, Jan, Halbedel, Sven, Dumke, Roger, Regula, Jorg, Gabdoulline, Razif R, Mayer, Frank, Stulke, Jorg, Herrmann, Richard
Published in Microbiology (Society for General Microbiology) (01.04.2008)
Published in Microbiology (Society for General Microbiology) (01.04.2008)
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Journal Article
Re-annotating the Mycoplasma pneumoniae genome sequence: adding value, function and reading frames
Dandekar, T, Huynen, M, Regula, J T, Ueberle, B, Zimmermann, C U, Andrade, M A, Doerks, T, Sánchez-Pulido, L, Snel, B, Suyama, M, Yuan, Y P, Herrmann, R, Bork, P
Published in Nucleic acids research (01.09.2000)
Published in Nucleic acids research (01.09.2000)
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Journal Article