Non-Canonical Hedgehog Signaling Is a Positive Regulator of the WNT Pathway and Is Required for the Survival of Colon Cancer Stem Cells
Regan, Joseph L., Schumacher, Dirk, Staudte, Stephanie, Steffen, Andreas, Haybaeck, Johannes, Keilholz, Ulrich, Schweiger, Caroline, Golob-Schwarzl, Nicole, Mumberg, Dominik, Henderson, David, Lehrach, Hans, Regenbrecht, Christian R.A., Schäfer, Reinhold, Lange, Martin
Published in Cell reports (Cambridge) (05.12.2017)
Published in Cell reports (Cambridge) (05.12.2017)
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Journal Article
Transcriptome analysis of mammary epithelial subpopulations identifies novel determinants of lineage commitment and cell fate
Kendrick, Howard, Regan, Joseph L, Magnay, Fiona-Ann, Grigoriadis, Anita, Mitsopoulos, Costas, Zvelebil, Marketa, Smalley, Matthew J
Published in BMC genomics (08.12.2008)
Published in BMC genomics (08.12.2008)
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Journal Article
PDE5 inhibition eliminates cancer stem cells via induction of PKA signaling
Klutzny, Saskia, Anurin, Anna, Nicke, Barbara, Regan, Joseph L., Lange, Martin, Schulze, Luise, Parczyk, Karsten, Steigemann, Patrick
Published in Cell death & disease (07.02.2018)
Published in Cell death & disease (07.02.2018)
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Journal Article
Aurora A Kinase Regulates Mammary Epithelial Cell Fate by Determining Mitotic Spindle Orientation in a Notch-Dependent Manner
Regan, Joseph L., Sourisseau, Tony, Soady, Kelly, Kendrick, Howard, McCarthy, Afshan, Tang, Chan, Brennan, Keith, Linardopoulos, Spiros, White, Donald E., Smalley, Matthew J.
Published in Cell reports (Cambridge) (11.07.2013)
Published in Cell reports (Cambridge) (11.07.2013)
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Identification of a neural development gene expression signature in colon cancer stem cells reveals a role for EGR2 in tumorigenesis
Regan, Joseph L., Schumacher, Dirk, Staudte, Stephanie, Steffen, Andreas, Lesche, Ralf, Toedling, Joern, Jourdan, Thibaud, Haybaeck, Johannes, Golob-Schwarzl, Nicole, Mumberg, Dominik, Henderson, David, Győrffy, Balázs, Regenbrecht, Christian R.A., Keilholz, Ulrich, Schäfer, Reinhold, Lange, Martin
Published in iScience (15.07.2022)
Published in iScience (15.07.2022)
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Journal Article
RNA sequencing of long-term label-retaining colon cancer stem cells identifies novel regulators of quiescence
Regan, Joseph L., Schumacher, Dirk, Staudte, Stephanie, Steffen, Andreas, Lesche, Ralf, Toedling, Joern, Jourdan, Thibaud, Haybaeck, Johannes, Mumberg, Dominik, Henderson, David, Győrffy, Balázs, Regenbrecht, Christian R.A., Keilholz, Ulrich, Schäfer, Reinhold, Lange, Martin
Published in iScience (25.06.2021)
Published in iScience (25.06.2021)
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Journal Article
MACC1 Regulates LGR5 to Promote Cancer Stem Cell Properties in Colorectal Cancer
Erdem, Müge, Lee, Kyung Hwan, Hardt, Markus, Regan, Joseph L, Kobelt, Dennis, Walther, Wolfgang, Mokrizkij, Margarita, Regenbrecht, Christian, Stein, Ulrike
Published in Cancers (31.01.2024)
Published in Cancers (31.01.2024)
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Journal Article
Isolation of Mouse Mammary Epithelial Subpopulations: A Comparison of Leading Methods
Smalley, Matthew J., Kendrick, Howard, Sheridan, Julie M., Regan, Joseph L., Prater, Michael D., Lindeman, Geoffrey J., Watson, Christine J., Visvader, Jane E., Stingl, John
Published in Journal of mammary gland biology and neoplasia (01.06.2012)
Published in Journal of mammary gland biology and neoplasia (01.06.2012)
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Journal Article
Abstract 1714: The role of Hedgehog signaling in the regulation of human colon cancer stem cells
Regan, Joseph L., Staudte, Stephanie, Schumacher, Dirk, Keilholz, Ulrich, Haybaeck, Johannes, Lehrach, Hans, Yaspo, Marie-Laure, Henderson, David, Steffen, Andreas, Toedling, Joern, Lesche, Ralf, Schaefer, Reinhold, Regenbrecht, Christian R., Mumberg, Dominik, Lange, Martin
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Abstract 1715: Whole transcriptome analysis of patient-derived 3D in vitro and xenograft models of colon cancer identifies placental genes required for the survival of cancer stem cells
Regan, Joseph L., Staudte, Stephanie, Schumacher, Dirk, Keilholz, Ulrich, Haybaeck, Johannes, Lehrach, Hans, Yaspo, Marie-Laure, Henderson, David, Steffen, Andreas, Toedling, Joern, Lesche, Ralf, Schaefer, Reinhold, Regenbrecht, Christian R., Mumberg, Dominik, Lange, Martin
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Pregnancy in the mature adult mouse does not alter the proportion of mammary epithelial stem/progenitor cells
Britt, Kara L, Kendrick, Howard, Regan, Joseph L, Molyneux, Gemma, Magnay, Fiona-Ann, Ashworth, Alan, Smalley, Matthew J
Published in Breast cancer research : BCR (01.01.2009)
Published in Breast cancer research : BCR (01.01.2009)
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Journal Article
Regulator of G-protein signalling 2 mRNA is differentially expressed in mammary epithelial subpopulations and over-expressed in the majority of breast cancers
Smalley, Matthew J, Iravani, Marjan, Leao, Maria, Grigoriadis, Anita, Kendrick, Howard, Dexter, Tim, Fenwick, Kerry, Regan, Joseph L, Britt, Kara, McDonald, Sarah, Lord, Christopher J, Mackay, Alan, Ashworth, Alan
Published in Breast cancer research : BCR (01.01.2007)
Published in Breast cancer research : BCR (01.01.2007)
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Abstract 977: 3D-models of patient-derived colon tumors for the identification of genetic factors important in the regulation of cancer stem cells
Regan, Joseph L., Schumacher, Dirk, Staudte, Stephanie, Boehnke, Karsten, Keilholz, Ulrich, Haybaeck, Johannes, Lehrach, Hans, Henderson, David, Schaefer, Reinhold, Regenbrecht, Christian R., Mumberg, Dominik, Lange, Martin
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Abstract 3875: Functional and molecular characterization of colon cancer stem cells in tumor heterogeneity and disease relapse using a 3D-model of patient-derived tumors
Regan, Joseph L., Schumacher, Dirk, Boehnke, Karsten, Davies, Cathrin, Keilholz, Ulrich, Haybaeck, Johannes, Reinhard, Christoph, Lehrach, Hans, Henderson, David, Schaefer, Reinhold, Regenbrecht, Christian, Lange, Martin
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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