General Synthesis of Persistent Trityl Radicals for EPR Imaging of Biological Systems
Reddy, T. Jagadeeswar, Iwama, Tetsuo, Halpern, Howard J, Rawal, Viresh H
Published in Journal of organic chemistry (12.07.2002)
Published in Journal of organic chemistry (12.07.2002)
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Inhibition of the Activation of Multiple Serine Proteases with a Cathepsin C Inhibitor Requires Sustained Exposure to Prevent Pro-enzyme Processing
Méthot, Nathalie, Rubin, Joel, Guay, Daniel, Beaulieu, Christian, Ethier, Diane, Reddy, T. Jagadeeswar, Riendeau, Denis, Percival, M. David
Published in The Journal of biological chemistry (20.07.2007)
Published in The Journal of biological chemistry (20.07.2007)
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In Vivo Inhibition of Serine Protease Processing Requires a High Fractional Inhibition of Cathepsin C
Méthot, Nathalie, Guay, Daniel, Rubin, Joel, Ethier, Diane, Ortega, Karen, Wong, Simon, Normandin, Denis, Beaulieu, Christian, Reddy, T Jagadeeswar, Riendeau, Denis, Percival, M David
Published in Molecular pharmacology (01.06.2008)
Published in Molecular pharmacology (01.06.2008)
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Design and synthesis of dipeptidyl nitriles as potent, selective, and reversible inhibitors of cathepsin C
Guay, Daniel, Beaulieu, Christian, Jagadeeswar Reddy, T., Zamboni, Robert, Methot, Nathalie, Rubin, Joel, Ethier, Diane, David Percival, M.
Published in Bioorganic & medicinal chemistry letters (15.09.2009)
Published in Bioorganic & medicinal chemistry letters (15.09.2009)
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Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 2: Tertiary amides
Chan, Laval, Pereira, Oswy, Reddy, T.Jagadeeswar, Das, Sanjoy K., Poisson, Carl, Courchesne, Marc, Proulx, Mélanie, Siddiqui, Arshad, Yannopoulos, Constantin G., Nguyen-Ba, Nghe, Roy, Caroline, Nasturica, Daniel, Moinet, Christophe, Bethell, Richard, Hamel, Martine, L'Heureux, Lucille, David, Maud, Nicolas, Olivier, Courtemanche-Asselin, Philippe, Brunette, Stéphanie, Bilimoria, Darius, Bédard, Jean
Published in Bioorganic & medicinal chemistry letters (09.02.2004)
Published in Bioorganic & medicinal chemistry letters (09.02.2004)
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Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 1: Sulfonamides
Chan, Laval, Das, Sanjoy K., Reddy, T.Jagadeeswar, Poisson, Carl, Proulx, Mélanie, Pereira, Oswy, Courchesne, Marc, Roy, Caroline, Wang, Wuyi, Siddiqui, Arshad, Yannopoulos, Constantin G., Nguyen-Ba, Nghe, Labrecque, Denis, Bethell, Richard, Hamel, Martine, Courtemanche-Asselin, Philippe, L'Heureux, Lucille, David, Maud, Nicolas, Olivier, Brunette, Stéphanie, Bilimoria, Darius, Bédard, Jean
Published in Bioorganic & medicinal chemistry letters (09.02.2004)
Published in Bioorganic & medicinal chemistry letters (09.02.2004)
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Identification of N,N-Disubstituted Phenylalanines as a Novel Class of Inhibitors of Hepatitis C NS5B Polymerase
Chan, Laval, Reddy, T. Jagadeeswar, Proulx, Mélanie, Das, Sanjoy K, Pereira, Oswy, Wang, Wuyi, Siddiqui, Arshad, Yannopoulos, Constantin G, Poisson, Carl, Turcotte, Nathalie, Drouin, Alexandre, Alaoui-Ismaili, M. Hicham, Bethell, Richard, Hamel, Martine, L'Heureux, Lucille, Bilimoria, Darius, Nguyen-Ba, Nghe
Published in Journal of medicinal chemistry (10.04.2003)
Published in Journal of medicinal chemistry (10.04.2003)
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Further SAR studies on novel small molecule inhibitors of the hepatitis C (HCV) NS5B polymerase
Reddy, T.Jagadeeswar, Chan, Laval, Turcotte, Nathalie, Proulx, Melanie, Pereira, Oswy Z., Das, Sanjoy K., Siddiqui, Arshad, Wang, Wuyi, Poisson, Carl, Yannopoulos, Constantin G., Bilimoria, Darius, L'Heureux, Lucille, Alaoui, Hicham M.A., Nguyen-Ba, Nghe
Published in Bioorganic & medicinal chemistry letters (06.10.2003)
Published in Bioorganic & medicinal chemistry letters (06.10.2003)
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HCV NS5B polymerase-bound conformation of a soluble sulfonamide inhibitor by 2D transferred NOESY
YANNOPOULOS, Constantin G, PING XU, PROULX, Melanie, HALAB, Lilianne, WUYI WANG, BEDARD, Jean, MORIN, Nicolas, HAMEL, Martine, NICOLAS, Olivier, BILIMORIA, Darius, L'HEUREUX, Lucille, BETHELL, Richard, FENG NI, DIONNE, Gervais, CHAN, Laval, PEREIRA, Oswy Z, JAGADEESWAR REDDY, T, DAS, Sanjoy K, POISSON, Carl, NGUYEN-BA, Nghe, TURCOTTE, Nathalie
Published in Bioorganic & medicinal chemistry letters (01.11.2004)
Published in Bioorganic & medicinal chemistry letters (01.11.2004)
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Synthesis and evaluation of NS5A inhibitors containing diverse heteroaromatic cores
Henderson, James A., Bilimoria, Darius, Bubenik, Monica, Cadilhac, Caroline, Cottrell, Kevin M., Denis, Francois, Dietrich, Evelyne, Ewing, Nigel, Falardeau, Guy, Giroux, Simon, L’Heureux, Lucille, Liu, Bingcan, Mani, Nagraj, Morris, Mark, Nicolas, Olivier, Pereira, Oswy Z., Poisson, Carl, Reddy, T. Jagadeeswar, Selliah, Subajini, Shawgo, Rebecca S., Vaillancourt, Louis, Wang, Jian, Xu, Jinwang, Chauret, Nathalie, Berlioz-Seux, Francoise, Chan, Laval C., Das, Sanjoy K., Grillot, Anne-Laure, Bennani, Youssef L., Maxwell, John P.
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
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Benzimidazole-containing HCV NS5A inhibitors: Effect of 4-substituted pyrrolidines in balancing genotype 1a and 1b potency
Henderson, James A., Bilimoria, Darius, Bubenik, Monica, Cadilhac, Caroline, Cottrell, Kevin M., Dietrich, Evelyne, Denis, Francois, Ewing, Nigel, Falardeau, Guy, Giroux, Simon, Grey, Ronald, L’Heureux, Lucille, Liu, Bingcan, Mani, Nagraj, Morris, Mark, Nicolas, Olivier, Pereira, Oswy Z., Poisson, Carl, Govinda Rao, B., Reddy, T. Jagadeeswar, Selliah, Subajini, Shawgo, Rebecca S., Vaillancourt, Louis, Wang, Jian, Yannopoulos, Constantin G., Chauret, Nathalie, Berlioz-Seux, Francoise, Chan, Laval C., Das, Sanjoy K., Grillot, Anne-Laure, Bennani, Youssef L., Maxwell, John P.
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
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Discovery of thienoimidazole-based HCV NS5A inhibitors. Part 1: C2-Symmetric inhibitors with diyne and biphenyl linkers
Giroux, Simon, Bilimoria, Darius, Cadilhac, Caroline, Cottrell, Kevin M., Denis, Francois, Dietrich, Evelyne, Ewing, Nigel, Henderson, James A., L’Heureux, Lucille, Mani, Nagraj, Morris, Mark, Nicolas, Olivier, Reddy, T. Jagadeeswar, Selliah, Subajini, Shawgo, Rebecca S., Xu, Jinwang, Chauret, Nathalie, Berlioz-Seux, Francoise, Chan, Laval C., Das, Sanjoy K., Grillot, Anne-Laure, Bennani, Youssef L., Maxwell, John P.
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
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Discovery of thienoimidazole-based HCV NS5A inhibitors. Part 2: Non-symmetric inhibitors with potent activity against genotype 1a and 1b
Giroux, Simon, Bilimoria, Darius, Cadilhac, Caroline, Cottrell, Kevin M., Denis, Francois, Dietrich, Evelyne, Ewing, Nigel, Henderson, James A., L’Heureux, Lucille, Mani, Nagraj, Morris, Mark, Nicolas, Olivier, Reddy, T. Jagadeeswar, Selliah, Subajini, Shawgo, Rebecca S., Xu, Jinwang, Chauret, Nathalie, Berlioz-Seux, Francoise, Chan, Laval C., Das, Sanjoy K., Grillot, Anne-Laure, Bennani, Youssef L., Maxwell, John P.
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
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Discovery of Thienoimidazole-Based HCV NS5A Genotype 1a and 1b Inhibitors
Giroux, Simon, Xu, Jinwang, Reddy, T. Jagadeeswar, Morris, Mark, Cottrell, Kevin M, Cadilhac, Caroline, Henderson, James A, Nicolas, Oliver, Bilimoria, Darius, Denis, Francois, Mani, Nagraj, Ewing, Nigel, Shawgo, Rebecca, L’Heureux, Lucille, Selliah, Subajini, Chan, Laval, Chauret, Nathalie, Berlioz-Seux, Francoise, Namchuk, Mark N, Grillot, Anne-Laure, Bennani, Youssef L, Das, Sanjoy K, Maxwell, John P
Published in ACS medicinal chemistry letters (13.03.2014)
Published in ACS medicinal chemistry letters (13.03.2014)
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