Identification of 2,2-Dimethylbutanoic Acid (HST5040), a Clinical Development Candidate for the Treatment of Propionic Acidemia and Methylmalonic Acidemia
Armstrong, Allison J, Henke, Brad R, Collado, Maria Sol, Taylor, Justin M, Pourtaheri, Taylor D, Dillberger, John E, Roper, Thomas D, Wamhoff, Brian R, Olson, Matthew W, Figler, Robert A, Hoang, Stephen A, Reardon, John E, Johns, Brian A
Published in Journal of medicinal chemistry (22.04.2021)
Published in Journal of medicinal chemistry (22.04.2021)
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A novel small molecule approach for the treatment of propionic and methylmalonic acidemias
Armstrong, Allison J., Collado, Maria Sol, Henke, Brad R., Olson, Matthew W., Hoang, Stephen A., Hamilton, Christin A., Pourtaheri, Taylor D., Chapman, Kimberly A., Summar, Marshall M., Johns, Brian A., Wamhoff, Brian R., Reardon, John E., Figler, Robert A.
Published in Molecular genetics and metabolism (01.05.2021)
Published in Molecular genetics and metabolism (01.05.2021)
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Ketohexokinase inhibition improves NASH by reducing fructose-induced steatosis and fibrogenesis
Shepherd, Emma L., Saborano, Raquel, Northall, Ellie, Matsuda, Kae, Ogino, Hitomi, Yashiro, Hiroaki, Pickens, Jason, Feaver, Ryan E., Cole, Banumathi K., Hoang, Stephen A., Lawson, Mark J., Olson, Matthew, Figler, Robert A., Reardon, John E., Nishigaki, Nobuhiro, Wamhoff, Brian R., Günther, Ulrich L., Hirschfield, Gideon, Erion, Derek M., Lalor, Patricia F.
Published in JHEP reports (01.04.2021)
Published in JHEP reports (01.04.2021)
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CXL-1020, a Novel Nitroxyl (HNO) Prodrug, Is More Effective than Milrinone in Models of Diastolic Dysfunction-A Cardiovascular Therapeutic: An Efficacy and Safety Study in the Rat
Roof, Steve R, Ueyama, Yukie, Mazhari, Reza, Hamlin, Robert L, Hartman, J Craig, Ziolo, Mark T, Reardon, John E, Del Rio, Carlos L
Published in Frontiers in physiology (10.11.2017)
Published in Frontiers in physiology (10.11.2017)
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Intravenous Infusion of the Novel HNO Donor BMS-986231 Is Associated With Beneficial Inotropic, Lusitropic, and Vasodilatory Properties in 2 Canine Models of Heart Failure
Hartman, J. Craig, PhD, del Rio, Carlos L., PhD, Reardon, John E., PhD, Zhang, Kefei, MD, Sabbah, Hani N., PhD
Published in JACC. Basic to translational science (01.10.2018)
Published in JACC. Basic to translational science (01.10.2018)
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Low Energy CO2 Capture Enabled by Biocatalyst Delivery System
Reardon, John, Bucholz, Tracy, Hulvey, Matthew, Tuttle, Jonathan, Shaffer, Alex, Pulvirenti, Dawn, Weber, Luke, Killian, Keith, Zaks, Aleksey
Published in Energy procedia (2014)
Published in Energy procedia (2014)
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Anxiety sensitivity and disgust sensitivity interact to predict contamination fears
Cisler, Josh M., Reardon, John M., Williams, Nathan L., Lohr, Jeffrey M.
Published in Personality and individual differences (01.04.2007)
Published in Personality and individual differences (01.04.2007)
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298: A single centre audit of 403 patients undergoing whole brain radiotherapy for cerebral metastases
Saeed, Zeeshan, Hanif, Sonja, Reardon, John, Davies, Kevin, Chandy, Edward
Published in Radiotherapy and oncology (01.05.2024)
Published in Radiotherapy and oncology (01.05.2024)
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2-amino-6-methoxypurine arabinoside: an agent for T-cell malignancies
LAMBE, C. U, AVERETT, D. R, PAFF, M. T, REARDON, J. E, WILSON, J. G, KRENITSKY, T. A
Published in Cancer research (Chicago, Ill.) (01.08.1995)
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Published in Cancer research (Chicago, Ill.) (01.08.1995)
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ACYL-COA DEHYDROGENASES (ACAD) SUBSTRATE PROMISCUITY EXPLAINS THE DIVERGENT PHENOTYPES ASSOCIATED WITH ACAD DEFICIENCIES
Collado, M. Sol, Armstrong, Allison, Figler, Robert, Hamilton, Christin, Pourtaheri, Taylor, Hoang, Steve, Wamhoff, Brian, Chapman, Kimberly, Summar, Marshall, Hertzog, Don, Olson, Matthew, Reardon, John
Published in Molecular genetics and metabolism (01.04.2022)
Published in Molecular genetics and metabolism (01.04.2022)
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Biochemical and anaplerotic applications of in vitro models of propionic acidemia and methylmalonic acidemia using patient-derived primary hepatocytes
Collado, M. Sol, Armstrong, Allison J., Olson, Matthew, Hoang, Stephen A., Day, Nathan, Summar, Marshall, Chapman, Kimberly A., Reardon, John, Figler, Robert A., Wamhoff, Brian R.
Published in Molecular genetics and metabolism (01.07.2020)
Published in Molecular genetics and metabolism (01.07.2020)
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eP256 - HST5040: An investigational oral small molecule therapy entering phase 2 clinical development for methylmalonic (MMA) and propionic (PA) acidemias
Cox, Gerald, Armstrong, Allison, Waller, Mavis, Hayes, Mark, Collado, Maria Sol, Henke, Brad, Summar, Marshall, Wamhoff, Brian, Reardon, John, Figler, Robert, Johns, Brian, Chapman, Kimberly
Published in Molecular genetics and metabolism (01.04.2021)
Published in Molecular genetics and metabolism (01.04.2021)
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