Total Synthesis of Vinblastine, Vincristine, Related Natural Products, and Key Structural Analogues
Ishikawa, Hayato, Colby, David A, Seto, Shigeki, Va, Porino, Tam, Annie, Kakei, Hiroyuki, Rayl, Thomas J, Hwang, Inkyu, Boger, Dale L
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Published in Journal of the American Chemical Society (08.04.2009)
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Structure−Activity Relationships of α-Ketooxazole Inhibitors of Fatty Acid Amide Hydrolase
Hardouin, Christophe, Kelso, Michael J, Romero, F. Anthony, Rayl, Thomas J, Leung, Donmienne, Hwang, Inkyu, Cravatt, Benjamin F, Boger, Dale L
Published in Journal of medicinal chemistry (12.07.2007)
Published in Journal of medicinal chemistry (12.07.2007)
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A Unique Class of Duocarmycin and CC-1065 Analogues Subject to Reductive Activation
Jin, Wei, Trzupek, John D, Rayl, Thomas J, Broward, Melinda A, Vielhauer, George A, Weir, Scott J, Hwang, Inkyu, Boger, Dale L
Published in Journal of the American Chemical Society (12.12.2007)
Published in Journal of the American Chemical Society (12.12.2007)
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Potent and Selective α-Ketoheterocycle-Based Inhibitors of the Anandamide and Oleamide Catabolizing Enzyme, Fatty Acid Amide Hydrolase
Romero, F. Anthony, Du, Wu, Hwang, Inkyu, Rayl, Thomas J, Kimball, F. Scott, Leung, Donmienne, Hoover, Heather S, Apodaca, Richard L, Breitenbucher, J. Guy, Cravatt, Benjamin F, Boger, Dale L
Published in Journal of medicinal chemistry (08.03.2007)
Published in Journal of medicinal chemistry (08.03.2007)
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Systematic Exploration of the Structural Features of Yatakemycin Impacting DNA Alkylation and Biological Activity
Tichenor, Mark S, MacMillan, Karen S, Trzupek, John D, Rayl, Thomas J, Hwang, Inkyu, Boger, Dale L
Published in Journal of the American Chemical Society (05.09.2007)
Published in Journal of the American Chemical Society (05.09.2007)
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Rational Design, Synthesis, and Evaluation of Key Analogues of CC-1065 and the Duocarmycins
Tichenor, Mark S, MacMillan, Karen S, Stover, James S, Wolkenberg, Scott E, Pavani, Maria G, Zanella, Lorenzo, Zaid, Abdel N, Spalluto, Gianpiero, Rayl, Thomas J, Hwang, Inkyu, Baraldi, Pier Giovanni, Boger, Dale L
Published in Journal of the American Chemical Society (14.11.2007)
Published in Journal of the American Chemical Society (14.11.2007)
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Synthesis and preliminary evaluation of duocarmycin analogues incorporating the 1,2,11,11a-tetrahydrocyclopropa[ c]naphtho[2,3- e]indol-4-one (CNI) and 1,2,11,11a-tetrahydrocyclopropa[ c]naphtho[1,2- e]indol-4-one ( iso-CNI) alkylation subunits
Gauss, Carla M., Hamasaki, Akiyuki, Parrish, Jay P., MacMillan, Karen S., Rayl, Thomas J., Hwang, Inkyu, Boger, Dale L.
Published in Tetrahedron (15.08.2009)
Published in Tetrahedron (15.08.2009)
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Journal Article
Synthesis and preliminary evaluation of duocarmycin analogues incorporating the 1,2,11,11a-tetrahydrocyclopropa[c]naphtho[2,3-e]indol-4-one (CNI) and 1,2,11,11a-tetrahydrocyclopropa[c]naphtho[1,2-e]indol-4-one (iso-CNI) alkylation subunits: 2008 Tetrahedron Prize for Creativity in Organic Chemistry. The Art of Synthesis: Methods, Strategies and Applications
GAUSS, Carla M, HAMASAKI, Akiyuki, PARRISH, Jay P, MACMILLAN, Karen S, RAYL, Thomas J, HWANG, Inkyu, BOGER, Dale L
Published in Tetrahedron (2009)
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Published in Tetrahedron (2009)
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Structure–Activity Relationships of α-Keto Oxazole Inhibitors of Fatty Acid Amide Hydrolase
Hardouin, Christophe, Kelso, Michael J., Romero, F. Anthony, Rayl, Thomas J., Leung, Donmienne, Hwang, Inkyu, Cravatt, Benjamin F., Boger, Dale L.
Published in Journal of medicinal chemistry (09.06.2007)
Published in Journal of medicinal chemistry (09.06.2007)
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Journal Article
Systematic Exploration of the Structural Features of Yatakemycin Impacting DNA Alkylation and Biological Activity
Tichenor, Mark S, MacMillan, Karen S, Trzupek, John D, Rayl, Thomas J, Hwang, Inkyu, Boger, Dale L
Published in Journal of the American Chemical Society (01.01.2007)
Published in Journal of the American Chemical Society (01.01.2007)
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Journal Article
A Unique Class of Duocarmycin and CC-1065 Analogues Subject to Reductive Activation
Jin, Wei, Trzupek, John D, Rayl, Thomas J, Broward, Melinda A, Vielhauer, George A, Weir, Scott J, Hwang, Inkyu, Boger, Dale L
Published in Journal of the American Chemical Society (01.01.2007)
Published in Journal of the American Chemical Society (01.01.2007)
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Journal Article
Rational Design, Synthesis, and Evaluation of Key Analogues of CC-1065 and the Duocarmycins
Tichenor, Mark S, MacMillan, Karen S, Stover, James S, Wolkenberg, Scott E, Pavani, Maria G, Zanella, Lorenzo, Zaid, Abdel N, Spalluto, Gianpiero, Rayl, Thomas J, Hwang, Inkyu, Baraldi, Pier Giovanni, Boger, Dale L
Published in Journal of the American Chemical Society (01.01.2007)
Published in Journal of the American Chemical Society (01.01.2007)
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