2,4-Diamino-5-benzylpyrimidines and analogs as antibacterial agents. 12. 1,2-Dihydroquinolylmethyl analogs with high activity and specificity for bacterial dihydrofolate reductase
Johnson, Jay V, Rauckman, Barbara S, Baccanari, David P, Roth, Barbara
Published in Journal of medicinal chemistry (01.08.1989)
Published in Journal of medicinal chemistry (01.08.1989)
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2,4-Diamino-5-benzylpyrimidines as antibacterial agents. 7. Analysis of the effect of 3,5-dialkyl substituent size and shape on binding to four different dihydrofolate reductase enzymes
Roth, Barbara, Rauckman, Barbara S, Ferone, Robert, Baccanari, David P, Champness, John N, Hyde, Richard M
Published in Journal of medicinal chemistry (01.02.1987)
Published in Journal of medicinal chemistry (01.02.1987)
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Journal Article
2,4-Diamino-5-benzylpyrimidines and analogs as antibacterial agents. 10. 2,4-Diamino-5-(6-quinolylmethyl)- and -[(tetrahydro-6-quinolyl)methyl]pyrimidine derivatives. Further specificity studies
Rauckman, Barbara S, Tidwell, Mary Y, Johnson, Jay V, Roth, Barbara
Published in Journal of medicinal chemistry (01.08.1989)
Published in Journal of medicinal chemistry (01.08.1989)
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Journal Article
2,4-Diamino-5-benzylpyrimidines and analogs as antibacterial agents. 2. C-Alkylation of pyrimidines with Mannich bases and application to the synthesis of trimethoprim and analogs
Roth, Barbara, Strelitz, Justina Z, Rauckman, Barbara S
Published in Journal of medicinal chemistry (01.04.1980)
Published in Journal of medicinal chemistry (01.04.1980)
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Journal Article
2,4-Diamino-5-benzylpyrimidines as antibacterial agents. 4. 6-Substituted trimethoprim derivatives from phenolic Mannich intermediates. Application to the synthesis of trimethoprim and 3,5-dialkylbenzyl analogs
Roth, Barbara, Aig, Edward, Lane, Kenneth, Rauckman, Barbara S
Published in Journal of medicinal chemistry (01.05.1980)
Published in Journal of medicinal chemistry (01.05.1980)
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Journal Article
2,4-Diamino-5-benzylpyrimidines and analogs as antibacterial agents. 5. 3',5'-Dimethoxy-4'-substituted-benzyl analogs of trimethoprim
Roth, Barbara, Aig, Edward, Rauckman, Barbara S, Strelitz, Justina Z, Phillips, Arthur P, Ferone, Robert, Bushby, S. R. M, Sigel, Carl W
Published in Journal of medicinal chemistry (01.08.1981)
Published in Journal of medicinal chemistry (01.08.1981)
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Journal Article
Extrusion of sulfur from [(acylmethyl)thio]pyrimidinones
Roth, Barbara, Laube, Renee, Tidwell, Mary Y, Rauckman, Barbara S
Published in Journal of organic chemistry (01.08.1980)
Published in Journal of organic chemistry (01.08.1980)
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Journal Article
Post-tyrosine intermediates in the biosynthesis of mesembrine alkaloids and stereochemistry of protonation at C-7 in the formation of the octahydroindole skeleton
Jeffs, Peter W., Johnson, David B., Martin, Ned H., Rauckman, Barbara S.
Published in Journal of the Chemical Society. Chemical communications (1976)
Published in Journal of the Chemical Society. Chemical communications (1976)
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Journal Article
PROCESS FOR PREPARING 2,4 DIAMINO 5-(SUBSTITUTED) PYRIMIDINES
RAUCKMAN BARBARA S, RODEMAN BARBARA S, SKONEZNY PAUL M, ROTH BARBARA, DALUGE SUSAN M
Year of Publication 19.02.1991
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Year of Publication 19.02.1991
Patent
Aryl-fused sphingolipids as novel PKC inhibitors with topical antiinflammatory activity
Tegeler, John J., Rauckman, Barbara S., Hamer, R.Richard L., Freed, Brian S., Merriman, Gregory H., Hellyer, Luther, Ortega-Nanos, Marie, Bailey, Steven C., Kurtz, Ellen S.
Published in Bioorganic & medicinal chemistry letters (02.11.1995)
Published in Bioorganic & medicinal chemistry letters (02.11.1995)
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Journal Article
The enantioselective synthesis and antiinflammatory activity of novel aryl-sphingolipid PKC inhibitors
Merriman, Gregory, Tegeler, John J., Hamer, R.Richard L., Rauckman, Barbara S., Freed, Brian S., Kurtz, Ellen S., Bailey, Steven C., Ortega-Nanos, Marie, Przekop, Penelope A., Hellyer, Luther
Published in Bioorganic & medicinal chemistry letters (02.11.1995)
Published in Bioorganic & medicinal chemistry letters (02.11.1995)
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COMPOSTOS DE PIRIMIDINA HIDRAZIDA COMO INIBIDORES DE PGDS
LAN MU, BRIAN PEDGRIFT, SUZANNE C. ALDOUS, BARBARA RAUCKMAN, GRZEGORZ T. STOKLOSA, SUKANTHINI THURAIRATNAM, MICHAEL W. FENNIE, CHRISTOPHER L. VAN-DEUSEN, JEFFREY S. SABOL, JOHN Z. JIANG, STANLY JOHN, JAMES R. PRIBISH
Year of Publication 07.10.2014
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Year of Publication 07.10.2014
Patent