Comprehensive Multi-omics Analysis Reveals Mitochondrial Stress as a Central Biological Hub for Spaceflight Impact
da Silveira, Willian A., Fazelinia, Hossein, Rosenthal, Sara Brin, Laiakis, Evagelia C., Kim, Man S., Meydan, Cem, Kidane, Yared, Rathi, Komal S., Smith, Scott M., Stear, Benjamin, Ying, Yue, Zhang, Yuanchao, Foox, Jonathan, Zanello, Susana, Crucian, Brian, Wang, Dong, Nugent, Adrienne, Costa, Helio A., Zwart, Sara R., Schrepfer, Sonja, Elworth, R.A. Leo, Sapoval, Nicolae, Treangen, Todd, MacKay, Matthew, Gokhale, Nandan S., Horner, Stacy M., Singh, Larry N., Wallace, Douglas C., Willey, Jeffrey S., Schisler, Jonathan C., Meller, Robert, McDonald, J. Tyson, Fisch, Kathleen M., Hardiman, Gary, Taylor, Deanne, Mason, Christopher E., Costes, Sylvain V., Beheshti, Afshin
Published in Cell (25.11.2020)
Published in Cell (25.11.2020)
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Journal Article
The ADP/ATP translocase drives mitophagy independent of nucleotide exchange
Hoshino, Atsushi, Wang, Wei-Jia, Wada, Shogo, McDermott-Roe, Chris, Evans, Chantell S, Gosis, Bridget, Morley, Michael P, Rathi, Komal S, Li, Jian, Li, Kristina, Yang, Steven, McManus, Meagan J, Bowman, Caitlyn, Potluri, Prasanth, Levin, Michael, Damrauer, Scott, Wallace, Douglas C, Holzbaur, Erika L F, Arany, Zoltan
Published in Nature (London) (01.11.2019)
Published in Nature (London) (01.11.2019)
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Journal Article
Hedgehog actively maintains adult lung quiescence and regulates repair and regeneration
Peng, Tien, Frank, David B, Kadzik, Rachel S, Morley, Michael P, Rathi, Komal S, Wang, Tao, Zhou, Su, Cheng, Lan, Lu, Min Min, Morrisey, Edward E
Published in Nature (London) (22.10.2015)
Published in Nature (London) (22.10.2015)
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Journal Article
Identification of GPC2 as an Oncoprotein and Candidate Immunotherapeutic Target in High-Risk Neuroblastoma
Bosse, Kristopher R., Raman, Pichai, Zhu, Zhongyu, Lane, Maria, Martinez, Daniel, Heitzeneder, Sabine, Rathi, Komal S., Kendsersky, Nathan M., Randall, Michael, Donovan, Laura, Morrissy, Sorana, Sussman, Robyn T., Zhelev, Doncho V., Feng, Yang, Wang, Yanping, Hwang, Jennifer, Lopez, Gonzalo, Harenza, Jo Lynne, Wei, Jun S., Pawel, Bruce, Bhatti, Tricia, Santi, Mariarita, Ganguly, Arupa, Khan, Javed, Marra, Marco A., Taylor, Michael D., Dimitrov, Dimiter S., Mackall, Crystal L., Maris, John M.
Published in Cancer cell (11.09.2017)
Published in Cancer cell (11.09.2017)
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Journal Article
Long noncoding RNAs are spatially correlated with transcription factors and regulate lung development
Herriges, Michael J, Swarr, Daniel T, Morley, Michael P, Rathi, Komal S, Peng, Tien, Stewart, Kathleen M, Morrisey, Edward E
Published in Genes & development (15.06.2014)
Published in Genes & development (15.06.2014)
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Journal Article
A transcriptome-based classifier to determine molecular subtypes in medulloblastoma
Rathi, Komal S, Arif, Sherjeel, Koptyra, Mateusz, Naqvi, Ammar S, Taylor, Deanne M, Storm, Phillip B, Resnick, Adam C, Rokita, Jo Lynne, Raman, Pichai
Published in PLoS computational biology (29.10.2020)
Published in PLoS computational biology (29.10.2020)
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Journal Article
Clinical utility of custom-designed NGS panel testing in pediatric tumors
Surrey, Lea F, MacFarland, Suzanne P, Chang, Fengqi, Cao, Kajia, Rathi, Komal S, Akgumus, Gozde T, Gallo, Daniel, Lin, Fumin, Gleason, Adam, Raman, Pichai, Aplenc, Richard, Bagatell, Rochelle, Minturn, Jane, Mosse, Yael, Santi, Mariarita, Tasian, Sarah K, Waanders, Angela J, Sarmady, Mahdi, Maris, John M, Hunger, Stephen P, Li, Marilyn M
Published in Genome medicine (28.05.2019)
Published in Genome medicine (28.05.2019)
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Journal Article
LIN28B promotes neuroblastoma metastasis and regulates PDZ binding kinase
Chen, Dongdong, Cox, Julie, Annam, Jayabhargav, Weingart, Melanie, Essien, Grace, Rathi, Komal S., Rokita, Jo Lynne, Khurana, Priya, Cuya, Selma M., Bosse, Kristopher R., Pilgrim, Adeiye, Li, Daisy, Shields, Cara, Laur, Oskar, Maris, John M., Schnepp, Robert W.
Published in Neoplasia (New York, N.Y.) (01.06.2020)
Published in Neoplasia (New York, N.Y.) (01.06.2020)
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Journal Article
Macrophages in SHH subgroup medulloblastoma display dynamic heterogeneity that varies with treatment modality
Dang, Mai T., Gonzalez, Michael V., Gaonkar, Krutika S., Rathi, Komal S., Young, Patricia, Arif, Sherjeel, Zhai, Li, Alam, Zahidul, Devalaraja, Samir, To, Tsun Ki Jerrick, Folkert, Ian W., Raman, Pichai, Rokita, Jo Lynne, Martinez, Daniel, Taroni, Jaclyn N., Shapiro, Joshua A., Greene, Casey S., Savonen, Candace, Mafra, Fernanda, Hakonarson, Hakon, Curran, Tom, Haldar, Malay
Published in Cell reports (Cambridge) (30.03.2021)
Published in Cell reports (Cambridge) (30.03.2021)
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Journal Article
GAS7 Deficiency Promotes Metastasis in MYCN-Driven Neuroblastoma
Dong, Zhiwei, Yeo, Kok Siong, Lopez, Gonzalo, Zhang, Cheng, Dankert Eggum, Erin N, Rokita, Jo Lynne, Ung, Choong Yong, Levee, Taylor M, Her, Zuag Paj, Howe, Cassie J, Hou, Xiaonan, van Ree, Janine H, Li, Shuai, He, Shuning, Tao, Ting, Fritchie, Karen, Torres-Mora, Jorge, Lehman, Julia S, Meves, Alexander, Razidlo, Gina L, Rathi, Komal S, Weroha, S John, Look, A Thomas, van Deursen, Jan M, Li, Hu, Westendorf, Jennifer J, Maris, John M, Zhu, Shizhen
Published in Cancer research (Chicago, Ill.) (01.06.2021)
Published in Cancer research (Chicago, Ill.) (01.06.2021)
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Journal Article
Targeting PARP-1 with Alpha-Particles Is Potently Cytotoxic to Human Neuroblastoma in Preclinical Models
Makvandi, Mehran, Lee, Hwan, Puentes, Laura N, Reilly, Sean W, Rathi, Komal S, Weng, Chi-Chang, Chan, Ho Sze, Hou, Catherine, Raman, Pichai, Martinez, Daniel, Xu, Kuiying, Carlin, Sean D, Greenberg, Roger A, Pawel, Bruce R, Mach, Robert H, Maris, John M, Pryma, Daniel A
Published in Molecular cancer therapeutics (01.07.2019)
Published in Molecular cancer therapeutics (01.07.2019)
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Journal Article
annoFuse: an R Package to annotate, prioritize, and interactively explore putative oncogenic RNA fusions
Gaonkar, Krutika S, Marini, Federico, Rathi, Komal S, Jain, Payal, Zhu, Yuankun, Chimicles, Nicholas A, Brown, Miguel A, Naqvi, Ammar S, Zhang, Bo, Storm, Phillip B, Maris, John M, Raman, Pichai, Resnick, Adam C, Strauch, Konstantin, Taroni, Jaclyn N, Rokita, Jo Lynne
Published in BMC bioinformatics (14.12.2020)
Published in BMC bioinformatics (14.12.2020)
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Journal Article
Somatic structural variation targets neurodevelopmental genes and identifies SHANK2 as a tumor suppressor in neuroblastoma
Lopez, Gonzalo, Conkrite, Karina L, Doepner, Miriam, Rathi, Komal S, Modi, Apexa, Vaksman, Zalman, Farra, Lance M, Hyson, Eric, Noureddine, Moataz, Wei, Jun S, Smith, Malcolm A, Asgharzadeh, Shahab, Seeger, Robert C, Khan, Javed, Auvil, Jaime Guidry, Gerhard, Daniela S, Maris, John M, Diskin, Sharon J
Published in Genome research (01.09.2020)
Published in Genome research (01.09.2020)
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Journal Article
Mitochondrial DNA Haplogroups and Susceptibility to Neuroblastoma
Chang, Xiao, Bakay, Marina, Liu, Yichuan, Glessner, Joseph, Rathi, Komal S, Hou, Cuiping, Qu, Huiqi, Vaksman, Zalman, Nguyen, Kenny, Sleiman, Patrick M A, Diskin, Sharon J, Maris, John M, Hakonarson, Hakon
Published in JNCI : Journal of the National Cancer Institute (14.12.2020)
Published in JNCI : Journal of the National Cancer Institute (14.12.2020)
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Journal Article
OBI-3424, a Novel AKR1C3-Activated Prodrug, Exhibits Potent Efficacy against Preclinical Models of T-ALL
Evans, Kathryn, Duan, JianXin, Pritchard, Tara, Jones, Connor D, McDermott, Lisa, Gu, Zhaohui, Toscan, Cara E, El-Zein, Narimanne, Mayoh, Chelsea, Erickson, Stephen W, Guo, Yuelong, Meng, Fanying, Jung, Donald, Rathi, Komal S, Roberts, Kathryn G, Mullighan, Charles G, Shia, Chi-Sheng, Pearce, Tillman, Teicher, Beverly A, Smith, Malcolm A, Lock, Richard B
Published in Clinical cancer research (15.07.2019)
Published in Clinical cancer research (15.07.2019)
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Journal Article
Macrophages in SHH subgroup medulloblastoma display dynamic heterogeneity that varies with treatment modality
Dang, Mai T., Gonzalez, Michael V., Gaonkar, Krutika S., Rathi, Komal S., Young, Patricia, Arif, Sherjeel, Zhai, Li, Alam, Zahidul, Devalaraja, Samir, Jerrick To, Tsun Ki, Folkert, Ian W., Raman, Pichai, Rokita, Jo Lynne, Martinez, Daniel, Taroni, Jaclyn N., Shapiro, Joshua A., Greene, Casey S., Savonen, Candace, Mafra, Fernanda, Hakonarson, Hakon, Curran, Tom, Haldar, Malay
Published in Cell reports (Cambridge) (27.06.2023)
Published in Cell reports (Cambridge) (27.06.2023)
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Journal Article
Epigenetic regulator BMI1 promotes alveolar rhabdomyosarcoma proliferation and constitutes a novel therapeutic target
Shields, Cara E., Potlapalli, Sindhu, Cuya‐Smith, Selma M., Chappell, Sarah K., Chen, Dongdong, Martinez, Daniel, Pogoriler, Jennifer, Rathi, Komal S., Patel, Shiv A., Oristian, Kristianne M., Linardic, Corinne M., Maris, John M., Haynes, Karmella A., Schnepp, Robert W.
Published in Molecular oncology (01.08.2021)
Published in Molecular oncology (01.08.2021)
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