The antimalarial drug mefloquine enhances TP53 premature termination codon readthrough by aminoglycoside G418
Ferguson, Michael W, Gerak, Chloe A N, Chow, Christalle C T, Rastelli, Ettore J, Elmore, Kyle E, Stahl, Florian, Hosseini-Farahabadi, Sara, Baradaran-Heravi, Alireza, Coltart, Don M, Roberge, Michel
Published in PloS one (23.05.2019)
Published in PloS one (23.05.2019)
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Journal Article
Deactivation of STAT3 and ERK and Activation of p38 in Ovarian Cancer Cells Treated with a Small Molecule Inhibitor of PTP4A3 Phosphatase
Lazo, John S, Isbell, Kelly N, Rastelli, Ettore J, Wipf, Peter, Sharlow, Elizabeth R
Published in The FASEB journal (01.05.2022)
Published in The FASEB journal (01.05.2022)
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Journal Article
Disruption of Ovarian Cancer STAT3 and p38 Signaling with a Small-Molecule Inhibitor of PTP4A3 Phosphatase
Lazo, John S, Isbell, Kelly N, Vasa, Sai Ashish, Llaneza, Danielle C, Rastelli, Ettore J, Wipf, Peter, Sharlow, Elizabeth R
Published in The Journal of pharmacology and experimental therapeutics (01.03.2023)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2023)
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Journal Article
A Concise and Highly Enantioselective Total Synthesis of (+)-anti- and (−)-syn-Mefloquine Hydrochloride: Definitive Absolute Stereochemical Assignment of the Mefloquines
Rastelli, Ettore J., Coltart, Don M.
Published in Angewandte Chemie (International ed.) (16.11.2015)
Published in Angewandte Chemie (International ed.) (16.11.2015)
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Journal Article
Synthesis and evaluation of bifunctional PTP4A3 phosphatase inhibitors activating the ER stress pathway
Rastelli, Ettore J., Sannino, Sara, Hart, Duncan J., Sharlow, Elizabeth R., Lazo, John S., Brodsky, Jeffrey L., Wipf, Peter
Published in Bioorganic & medicinal chemistry letters (15.08.2021)
Published in Bioorganic & medicinal chemistry letters (15.08.2021)
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Journal Article
Next-Generation Cell-Active Inhibitors of the Undrugged Oncogenic PTP4A3 Phosphatase
Lazo, John S, Blanco, Isabella K, Tasker, Nikhil R, Rastelli, Ettore J, Burnett, James C, Garrott, Sharon R, Hart, Duncan J, McCloud, Rebecca L, Hsu, Ku-Lung, Wipf, Peter, Sharlow, Elizabeth R
Published in The Journal of pharmacology and experimental therapeutics (01.12.2019)
Published in The Journal of pharmacology and experimental therapeutics (01.12.2019)
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Journal Article
Tapping the therapeutic potential of protein tyrosine phosphatase 4A with small molecule inhibitors
Tasker, Nikhil R., Rastelli, Ettore J., Burnett, James C., Sharlow, Elizabeth R., Lazo, John S., Wipf, Peter
Published in Bioorganic & medicinal chemistry letters (15.08.2019)
Published in Bioorganic & medicinal chemistry letters (15.08.2019)
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Journal Article
Structure of the Complex of an Iminopyridinedione Protein Tyrosine Phosphatase 4A3 Phosphatase Inhibitor with Human Serum Albumin
Czub, Mateusz P, Boulton, Adam M, Rastelli, Ettore J, Tasker, Nikhil R, Maskrey, Taber S, Blanco, Isabella K, McQueeney, Kelley E, Bushweller, John H, Minor, Wladek, Wipf, Peter, Sharlow, Elizabeth R, Lazo, John S
Published in Molecular pharmacology (01.12.2020)
Published in Molecular pharmacology (01.12.2020)
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Journal Article
In-flow photooxygenation of aminothienopyridinones generates iminopyridinedione PTP4A3 phosphatase inhibitors
Tasker, Nikhil R., Rastelli, Ettore J., Blanco, Isabella K., Burnett, James C., Sharlow, Elizabeth R., Lazo, John S., Wipf, Peter
Published in Organic & biomolecular chemistry (27.02.2019)
Published in Organic & biomolecular chemistry (27.02.2019)
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Journal Article
On the Mechanism of the Asymmetric Aldol Addition of Chiral N‐Amino Cyclic Carbamate Hydrazones: Evidence of Non‐Curtin–Hammett Behavior
Uddin, Md. Nasir, Knight, John D., Rastelli, Ettore J., Soubra‐Ghaoui, Chirine, Albright, Thomas A., Wu, Chia‐Hua, Wu, Judy I., Coltart, Don M.
Published in Chemistry : a European journal (13.12.2019)
Published in Chemistry : a European journal (13.12.2019)
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Journal Article
Credentialing and Pharmacologically Targeting PTP4A3 Phosphatase as a Molecular Target for Ovarian Cancer
Lazo, John S, Sharlow, Elizabeth R, Cornelison, Robert, Hart, Duncan J, Llaneza, Danielle C, Mendelson, Anna J, Rastelli, Ettore J, Tasker, Nikhil R, Landen, Jr, Charles N, Wipf, Peter
Published in Biomolecules (Basel, Switzerland) (30.06.2021)
Published in Biomolecules (Basel, Switzerland) (30.06.2021)
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Journal Article
The apratoxin marine natural products: isolation, structure determination, and asymmetric total synthesis
Tarsis, Emily M., Rastelli, Ettore J., Wengryniuk, Sarah E., Coltart, Don M.
Published in Tetrahedron (05.08.2015)
Published in Tetrahedron (05.08.2015)
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Journal Article
3D-printed cartridge system for in-flow photo-oxygenation of 7-aminothienopyridinones
Rastelli, Ettore J., Yue, Doris, Millard, Caroline, Wipf, Peter
Published in Tetrahedron (22.01.2021)
Published in Tetrahedron (22.01.2021)
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Journal Article
Abstract 1459: PTP4A3 phosphatase is a novel drug target for epithelial ovarian cancer
Cornelison, John Robert, Rastelli, Ettore J., Hart, Duncan J., Mendelson, Anna J., Sharlow, Elizabeth R., Wipf, Peter, Lazo, John S.
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Abstract 1460: The design and biological characterization of PTP4A-targeted chemodegraders
Hart, Duncan J., Rastelli, Ettore J., Mendelson, Anna J., Letai, Christopher T., Cornelison, John Robert, Sharlow, Elizabeth R., Wipf, Peter, Lazo, John S.
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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