CR011, a fully human monoclonal antibody-auristatin E conjugate, for the treatment of melanoma
KAM FAI TSE, JEFFERS, Michael, MACDOUGALL, John R, RASTELLI, Luca, HERRMANN, John, GALLO, Michael, GAZIT-BORNSTEIN, Gadi, SENTER, Peter D, MEYER, Damon L, LICHENSTEIN, Henri S, LAROCHELLE, William J, POLLACK, Vincent A, MCCABE, Denise A, SHADISH, Melanie L, KHRAMTSOV, Nikolai V, HACKETT, Craig S, SHENOY, Suresh G, BING KUANG, BOLDOG, Ferenc L
Published in Clinical cancer research (15.02.2006)
Published in Clinical cancer research (15.02.2006)
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Journal Article
635 A novel site-directed chemical conjugation technology confers antitumor activity via native Fc receptor to plasma immunoglobulin by attaching tumor binders
Vidal, Christian, Cukan, Michael, Varma, Rajat, Iben, Lawrence, Berbasova, Tanya, Vaill, Ada, Bunin, Anna, Rossi, Ann Marie, Trinh, David, McGrath, Katy, Alvarez, Enrique, Welsch, Matthew, Rastelli, Luca
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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Journal Article
Reconstitution of Enhancer Function in Paternal Pronuclei of One-Cell Mouse Embryos
Rastelli, Luca, Robinson, Karen, Xu, Yanbo, Majumder, Sadhan
Published in Molecular and Cellular Biology (01.08.2001)
Published in Molecular and Cellular Biology (01.08.2001)
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Journal Article
A first-in-class ex vivo combination between cytokine-induced memory like (CIML) NK cells and a CD38 targeting antibody recruiting molecule (ARM) as a novel approach to target NK cells without cellular engineering for the treatment of multiple myeloma
Rastelli, Luca, Mohsin, Maqbool, Rossi, Ann Marie, Alvarez Sotomayor, Enrique, Iben, Lawrence, Vaill, Ada, Welsch, Matthew, Romee, Rizwan, Bunin, Anna
Published in Journal of clinical oncology (20.05.2020)
Published in Journal of clinical oncology (20.05.2020)
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Journal Article
Lack of Enhancer Function in Mammals Is Unique to Oocytes and Fertilized Eggs
Lawinger, P, Rastelli, L, Zhao, Z, Majumder, S
Published in The Journal of biological chemistry (19.03.1999)
Published in The Journal of biological chemistry (19.03.1999)
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A Novel Class of Bifunctional Immunotherapeutic That Exploits a Universal Antibody Binding Terminus (uABT) to Recruit Endogenous Antibodies to Cell Expressing CD38 Demonstrate In Vivo efficacy in Three Distinct Animal Models
Bunin, Anna, McGrath, Katy, Rossi, Ann Marie, Welsch, Matthew, Vidal, Christian, Trinh, David, Spiegel, David, Rastelli, Luca, Alvarez, Enrique
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Journal Article
Efficacy and immune modulation by BXCL701 a dipeptidyl peptidase inhibitor, NKTR-214 a CD122-biased immune agonist with PD1 blockade in murine pancreatic tumors
Rastelli, Luca, Gupta, Snigdha, Jagga, Zeenia, Charych, Deborah H., Zalevsky, Jonathan
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
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Journal Article
KPMW135, a Biosuperior CD3 Bispecific Version of Rituximab Created By a Novel Chemical Conjugation Technology Demonstrates Increased Anti-Tumor Activity By Adding T Cell-Mediated Cytotoxicity Activity to the Existing Mechanisms of Rituximab
Vidal, Christian, Cukan, Michael, Vaill, Ada, Bunin, Anna, Rossi, Ann Marie, Iben, Lawrence, Trinh, David, McGrath, Katy, Berbasova, Tanya, Romee, Rizwan, Alvarez, Enrique, Rastelli, Luca, Welsch, Matthew
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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Journal Article
Abstract 2629: The synergy between BXCL701, a DPP inhibitor, and immune checkpoint inhibitors discovered using AI and Big Data analytics
Rastelli, Luca, Gupta, Snigdha, Dahiya, Akhil, Jagga, Zeenia, Nandabalan, Krishnan, Upmanyu, Sanatan
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Novel, small molecule inhibitors of PD-1/PD-L1 pathway
Rastelli, Luca, Rajagopal, Sridharan, Gajendran, Chandru, Sadhu, Naveen M., Mohd, Zainuddin, Gosu, Ramachandraiah, Friedmann-Morvinski, Dinorah, Kandan, Saravanan, Birudukota, Swarnakumari, S, Srinivasan, V, Krishnakumar, Wahid, Saif, Siddiqui, Amir, Viswakarma, Santosh, Narayan, Ashwini, G, Rudresh, Mullurwar, Sadanand R., Sher, Divsha, Mansur, Shahar, Sivanandhan, Dhanalakshmi
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
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Abstract 1478: Human transgenic IL-15 NOG mice reconstituted with human NK cells as a model for NK cell depletion
Bunin, Anna, Rossi, Ann Marie, Vidal, Christian, Trihn, David, Garcia, Marco, Woska, Joseph, Iben, Lawrence, Rastelli, Luca, Volden, Paul, Alvarez, Enrique
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Abstract B029: LSD1-HDAC6 dual inhibitor JBI-802 is an epigenetic modulating agent with a novel mechanism of action that target MYC amplification in multiple neuroendocrine tumor types
Sivanandhan, Dhanalakshmi, Rajagopal, Sridharan, Gajendran, Chandru, Sadhu, Naveen, Zainuddin, Mohd, Gosu, Ramachandraiah, Rastelli, Luca
Published in Cancer research (Chicago, Ill.) (01.12.2022)
Published in Cancer research (Chicago, Ill.) (01.12.2022)
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Journal Article
1386 Novel gut-restricted small molecule inhibitor of PD-L1 for targeting GI cancers
Sivanandhan, Dhanalakshmi, Sridharan Rajagopal, Gajendran, Chandru, Naveen, Sadhu M, Zainuddin, Mohammed, Ramachandraiah Gosu, Rastelli, Luca
Published in Journal for immunotherapy of cancer (01.11.2022)
Published in Journal for immunotherapy of cancer (01.11.2022)
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Journal Article
A Novel Class of Bifunctional Immunotherapeutic That Exploit a Universal Antibody Binding Terminus (uABT) to Recruit Endogenous Antibodies to Cells Expressing CD38 Demonstrates Anti-Multiple Myeloma Activity in Vitro and Ex Vivo against Patient Tumor Cells
Rossi, Ann Marie, Bunin, Anna, Iben, Lawrence, Welsch, Matthew, Berbasova, Tanya, Riillo, Caterina, Rossi, Marco, Ohuchi, Masaki, Alvarez, Enrique, Kawakami, Naoko, Nagasawa, Takayuki, Tassone, Pierfrancesco, Spiegel, David, Rastelli, Luca
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Journal Article
Blockade of the MEK/ERK signalling cascade by AS703026, a novel selective MEK1/2 inhibitor, induces pleiotropic anti‐myeloma activity in vitro and in vivo
Kim, Kihyun, Kong, Sun‐Young, Fulciniti, Mariateresa, Li, Xianfeng, Song, Weihua, Nahar, Sabikun, Burger, Peter, Rumizen, Mathew J., Podar, Klaus, Chauhan, Dharminder, Hideshima, Teru, Munshi, Nikhil C., Richardson, Paul, Clark, Ann, Ogden, Janet, Goutopoulos, Andreas, Rastelli, Luca, Anderson, Kenneth C., Tai, Yu‐Tzu
Published in British journal of haematology (01.05.2010)
Published in British journal of haematology (01.05.2010)
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Journal Article
The Melanoma Vascular Mimicry Phenotype Defined in Gene Expression and Microsome Sequencing Analysis
JINGFANG JU, LUCA RASTELLI, URIEL M. MALYANKER, JAN F. SIMONS, CHUNLI HUANG, JOHN HERRMANN, JOHN R. MACDOUGALL, BRUCE E. TAILLON
Published in Cancer genomics & proteomics (01.09.2004)
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Published in Cancer genomics & proteomics (01.09.2004)
Journal Article
Abstract 6269: JBI-778, a novel brain-penetrant small molecule PRMT5 inhibitor for treatment of cancer
Sivanandhan, Dhanalakshmi, Gajendran, Chandru, M, Naveen Sadhu, Mohammed, Zainuddin, Gosu, Ramachandraiah, Sher, Divsha, Mansur, Shahar, Friedmann-Morvinski, Dinorah, Rajagopal, Sridharan, Rastelli, Luca
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
CD38-결합제 및 이의 용도
BUNIN ANNA, RASTELLI LUCA, WELSCH MATTHEW ERNEST, BERBASOVA TETYANA, ROSSI ANN MARIE K
Year of Publication 04.04.2022
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Year of Publication 04.04.2022
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