In vivo selective inhibition of TRPC6 by antagonist BI 749327 ameliorates fibrosis and dysfunction in cardiac and renal disease
Lin, Brian Leei, Matera, Damian, Doerner, Julia F., Zheng, Nan, del Camino, Donato, Mishra, Sumita, Bian, Hong, Zeveleva, Svetlana, Zhen, Xiaoguang, Blair, Nathaniel T., Chong, Jayhong A., Hessler, David P., Bedja, Djahida, Zhu, Guangshuo, Muller, Grace K., Ranek, Mark J., Pantages, Lynn, McFarland, Mary, Netherton, Matthew R., Berry, Angela, Wong, Diane, Rast, Georg, Qian, Hu Sheng, Weldon, Steven M., Kuo, Jay J., Sauer, Achim, Sarko, Chris, Moran, Magdalene M., Kass, David A., Pullen, Steven S.
Published in Proceedings of the National Academy of Sciences - PNAS (14.05.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (14.05.2019)
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Journal Article
Treatment with HC-070, a potent inhibitor of TRPC4 and TRPC5, leads to anxiolytic and antidepressant effects in mice
Just, Stefan, Chenard, Bertrand L, Ceci, Angelo, Strassmaier, Timothy, Chong, Jayhong A, Blair, Nathaniel T, Gallaschun, Randall J, Del Camino, Donato, Cantin, Susan, D'Amours, Marc, Eickmeier, Christian, Fanger, Christopher M, Hecker, Carsten, Hessler, David P, Hengerer, Bastian, Kroker, Katja S, Malekiani, Sam, Mihalek, Robert, McLaughlin, Joseph, Rast, Georg, Witek, JoAnn, Sauer, Achim, Pryce, Christopher R, Moran, Magdalene M
Published in PloS one (31.01.2018)
Published in PloS one (31.01.2018)
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Journal Article
Ion Channel Expression and Electrophysiology of Singular Human (Primary and Induced Pluripotent Stem Cell-Derived) Cardiomyocytes
Schmid, Christina, Abi-Gerges, Najah, Leitner, Michael Georg, Zellner, Dietmar, Rast, Georg
Published in Cells (Basel, Switzerland) (30.11.2021)
Published in Cells (Basel, Switzerland) (30.11.2021)
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Journal Article
Influence of field potential duration on spontaneous beating rate of human induced pluripotent stem cell-derived cardiomyocytes: Implications for data analysis and test system selection
Rast, Georg, Kraushaar, Udo, Buckenmaier, Sandra, Ittrich, Carina, Guth, Brian D.
Published in Journal of pharmacological and toxicological methods (01.11.2016)
Published in Journal of pharmacological and toxicological methods (01.11.2016)
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Journal Article
Potent Inhibition of Ca2+ Release-activated Ca2+ Channels and T-lymphocyte Activation by the Pyrazole Derivative BTP2
Zitt, Christof, Strauss, Bettina, Schwarz, Eva C., Spaeth, Nicola, Rast, Georg, Hatzelmann, Armin, Hoth, Markus
Published in The Journal of biological chemistry (26.03.2004)
Published in The Journal of biological chemistry (26.03.2004)
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Journal Article
Behavioral Deficits and Subregion-Specific Suppression of LTP in Mice Expressing a Population of Mutant NMDA Receptors throughout the Hippocampus
Chen, Philip E, Errington, Michael L, Kneussel, Matthias, Chen, Guiquan, Annala, Alexander J, Rudhard, York H, Rast, Georg F, Specht, Christian G, Tigaret, Cezar M, Nassar, Mohammed A, Morris, Richard G.M, Bliss, Timothy V. P, Schoepfer, Ralf
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01.10.2009)
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01.10.2009)
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Journal Article
Subcellular localisation of recombinant α- and γ-synuclein
Specht, Christian G., Tigaret, Cezar M., Rast, Georg F., Thalhammer, Agnes, Rudhard, York, Schoepfer, Ralf
Published in Molecular and cellular neuroscience (01.02.2005)
Published in Molecular and cellular neuroscience (01.02.2005)
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Journal Article
Heterogeneity of hiPSC-derived cardiomyocytes
Schmid, Christina, Rast, Georg
Published in Journal of pharmacological and toxicological methods (01.09.2020)
Published in Journal of pharmacological and toxicological methods (01.09.2020)
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Journal Article
Absence of Whisker-Related Pattern Formation in Mice with NMDA Receptors Lacking Coincidence Detection Properties and Calcium Signaling
Rudhard, York, Kneussel, Matthias, Nassar, Mohammed A, Rast, Georg F, Annala, Alexander J, Chen, Philip E, Tigaret, Cezar M, Dean, Isabel, Roes, Juergen, Gibb, Alasdair J, Hunt, Stephen P, Schoepfer, Ralf
Published in The Journal of neuroscience (15.03.2003)
Published in The Journal of neuroscience (15.03.2003)
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Journal Article
Virtual clinical QT exposure-response studies – A translational computational approach
Aguado-Sierra, Jazmin, Dominguez-Gomez, Paula, Amar, Ani, Butakoff, Constantine, Leitner, Michael, Schaper, Stefan, Kriegl, Jan M., Darpo, Borje, Vazquez, Mariano, Rast, Georg
Published in Journal of pharmacological and toxicological methods (01.03.2024)
Published in Journal of pharmacological and toxicological methods (01.03.2024)
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Journal Article
Discovery of BI 7446: A Potent Cyclic Dinucleotide STING Agonist with Broad-Spectrum Variant Activity for the Treatment of Cancer
Kuttruff, Christian A., Fleck, Martin, Carotta, Sebastian, Arnhof, Heribert, Bretschneider, Tom, Dahmann, Georg, Gremel, Gabriela, Grube, Achim, Handschuh, Sandra, Heimann, Annekatrin, Hofmann, Marco H., Impagnatiello, Maria A., Nar, Herbert, Rast, Georg, Schaaf, Otmar, Schmidt, Esther, Oost, Thorsten
Published in Journal of medicinal chemistry (27.07.2023)
Published in Journal of medicinal chemistry (27.07.2023)
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Journal Article
Optimization of bioanalysis of dried blood samples
Alizadeh, Elham Ataei, Rast, Georg, Cantow, Chris, Schiwon, Jessica, Krause, Florian, De Meyer, Guido R.Y., Guns, Pieter-Jan, Guth, Brian D., Markert, Michael
Published in Journal of pharmacological and toxicological methods (01.09.2023)
Published in Journal of pharmacological and toxicological methods (01.09.2023)
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Journal Article
Inhibition of acetylcholinesterase and phosphodiesterase-9A has differential effects on hippocampal early and late LTP
Kroker, Katja S., Rast, Georg, Giovannini, Riccardo, Marti, Anelise, Dorner-Ciossek, Cornelia, Rosenbrock, Holger
Published in Neuropharmacology (01.04.2012)
Published in Neuropharmacology (01.04.2012)
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Journal Article
A multi-slice recording system for stable late phase hippocampal long-term potentiation experiments
Kroker, Katja Sabine, Rosenbrock, Holger, Rast, Georg
Published in Journal of neuroscience methods (15.01.2011)
Published in Journal of neuroscience methods (15.01.2011)
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Journal Article
Restoring long-term potentiation impaired by amyloid-beta oligomers: Comparison of an acetylcholinesterase inhibitior and selective neuronal nicotinic receptor agonists
Kroker, Katja S, Moreth, Jens, Kussmaul, Lothar, Rast, Georg, Rosenbrock, Holger
Published in Brain research bulletin (01.07.2013)
Published in Brain research bulletin (01.07.2013)
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