SIRT5 Regulates both Cytosolic and Mitochondrial Protein Malonylation with Glycolysis as a Major Target
Nishida, Yuya, Rardin, Matthew J., Carrico, Chris, He, Wenjuan, Sahu, Alexandria K., Gut, Philipp, Najjar, Rami, Fitch, Mark, Hellerstein, Marc, Gibson, Bradford W., Verdin, Eric
Published in Molecular cell (16.07.2015)
Published in Molecular cell (16.07.2015)
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Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways
Rardin, Matthew J., Newman, John C., Held, Jason M., Cusack, Michael P., Sorensen, Dylan J., Li, Biao, Schilling, Birgit, Mooney, Sean D., Kahn, C. Ronald, Verdin, Eric, Gibson, Bradford W.
Published in Proceedings of the National Academy of Sciences - PNAS (16.04.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (16.04.2013)
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Journal Article
SIRT5 Regulates the Mitochondrial Lysine Succinylome and Metabolic Networks
Rardin, Matthew J., He, Wenjuan, Nishida, Yuya, Newman, John C., Carrico, Chris, Danielson, Steven R., Guo, Ailan, Gut, Philipp, Sahu, Alexandria K., Li, Biao, Uppala, Radha, Fitch, Mark, Riiff, Timothy, Zhu, Lei, Zhou, Jing, Mulhern, Daniel, Stevens, Robert D., Ilkayeva, Olga R., Newgard, Christopher B., Jacobson, Matthew P., Hellerstein, Marc, Goetzman, Eric S., Gibson, Bradford W., Verdin, Eric
Published in Cell metabolism (03.12.2013)
Published in Cell metabolism (03.12.2013)
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Journal Article
Sirt3 Regulates Metabolic Flexibility of Skeletal Muscle Through Reversible Enzymatic Deacetylation
ENXUAN JING, O'NEILL, Brian T, GIBSON, Bradford W, KAHN, C. Ronald, RARDIN, Matthew J, KLEINRIDDERS, André, ILKEYEVA, Olga R, USSAR, Siegfried, BAIN, James R, LEE, Kevin Y, VERDIN, Eric M, NEWGARD, Christopher B
Published in Diabetes (New York, N.Y.) (01.10.2013)
Published in Diabetes (New York, N.Y.) (01.10.2013)
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Adipose-Specific Deletion of TFAM Increases Mitochondrial Oxidation and Protects Mice against Obesity and Insulin Resistance
Vernochet, Cecile, Mourier, Arnaud, Bezy, Olivier, Macotela, Yazmin, Boucher, Jeremie, Rardin, Matthew J., An, Ding, Lee, Kevin Y., Ilkayeva, Olga R., Zingaretti, Cristina M., Emanuelli, Brice, Smyth, Graham, Cinti, Saverio, Newgard, Christopher B., Gibson, Bradford W., Larsson, Nils-Göran, Kahn, C. Ronald
Published in Cell metabolism (05.12.2012)
Published in Cell metabolism (05.12.2012)
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Journal Article
Temporal dynamics of liver mitochondrial protein acetylation and succinylation and metabolites due to high fat diet and/or excess glucose or fructose
Meyer, Jesse G, Softic, Samir, Basisty, Nathan, Rardin, Matthew J, Verdin, Eric, Gibson, Bradford W, Ilkayeva, Olga, Newgard, Christopher B, Kahn, C Ronald, Schilling, Birgit
Published in PloS one (26.12.2018)
Published in PloS one (26.12.2018)
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Journal Article
Characterization of a Novel FLT3 BiTE Molecule for the Treatment of Acute Myeloid Leukemia
Brauchle, Bettina, Goldstein, Rebecca L., Karbowski, Christine M., Henn, Anja, Li, Chi-Ming, Bücklein, Veit L., Krupka, Christina, Boyle, Michael C., Koppikar, Priya, Haubner, Sascha, Wahl, Joachim, Dahlhoff, Christoph, Raum, Tobias, Rardin, Matthew J., Sastri, Christine, Rock, Dan A., von Bergwelt-Baildon, Michael, Frank, Brendon, Metzeler, Klaus H., Case, Ryan, Friedrich, Matthias, Balazs, Mercedesz, Spiekermann, Karsten, Coxon, Angela, Subklewe, Marion, Arvedson, Tara
Published in Molecular cancer therapeutics (01.09.2020)
Published in Molecular cancer therapeutics (01.09.2020)
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A novel splice variant of Elp3/Kat9 regulates mitochondrial tRNA modification and function
Boutoual, Rachid, Jo, Hyunsun, Heckenbach, Indra, Tiwari, Ritesh, Kasler, Herbert, Lerner, Chad A., Shah, Samah, Schilling, Birgit, Calvanese, Vincenzo, Rardin, Matthew J., Scheibye-Knudsen, Morten, Verdin, Eric
Published in Scientific reports (31.08.2022)
Published in Scientific reports (31.08.2022)
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Journal Article
MS1 Peptide Ion Intensity Chromatograms in MS2 (SWATH) Data Independent Acquisitions. Improving Post Acquisition Analysis of Proteomic Experiments[S]
Rardin, Matthew J., Schilling, Birgit, Cheng, Lin-Yang, MacLean, Brendan X., Sorensen, Dylan J., Sahu, Alexandria K., MacCoss, Michael J., Vitek, Olga, Gibson, Bradford W.
Published in Molecular & cellular proteomics (01.09.2015)
Published in Molecular & cellular proteomics (01.09.2015)
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Journal Article
Monitoring phosphorylation of the pyruvate dehydrogenase complex
Rardin, Matthew J., Wiley, Sandra E., Naviaux, Robert K., Murphy, Anne N., Dixon, Jack E.
Published in Analytical biochemistry (15.06.2009)
Published in Analytical biochemistry (15.06.2009)
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Journal Article
type III effector EspF coordinates membrane trafficking by the spatiotemporal activation of two eukaryotic signaling pathways
Alto, Neal M, Weflen, Andrew W, Rardin, Matthew J, Yarar, Defne, Lazar, Cheri S, Tonikian, Raffi, Koller, Antonius, Taylor, Susan S, Boone, Charles, Sidhu, Sachdev S, Schmid, Sandra L, Hecht, Gail A, Dixon, Jack E
Published in The Journal of cell biology (24.09.2007)
Published in The Journal of cell biology (24.09.2007)
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Platform-independent and label-free quantitation of proteomic data using MS1 extracted ion chromatograms in skyline: application to protein acetylation and phosphorylation
Schilling, Birgit, Rardin, Matthew J, MacLean, Brendan X, Zawadzka, Anna M, Frewen, Barbara E, Cusack, Michael P, Sorensen, Dylan J, Bereman, Michael S, Jing, Enxuan, Wu, Christine C, Verdin, Eric, Kahn, C Ronald, Maccoss, Michael J, Gibson, Bradford W
Published in Molecular & cellular proteomics (01.05.2012)
Published in Molecular & cellular proteomics (01.05.2012)
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Journal Article
Lysine desuccinylase SIRT5 binds to cardiolipin and regulates the electron transport chain
Zhang, Yuxun, Bharathi, Sivakama S., Rardin, Matthew J., Lu, Jie, Maringer, Katherine V., Sims-Lucas, Sunder, Prochownik, Edward V., Gibson, Bradford W., Goetzman, Eric S.
Published in The Journal of biological chemistry (16.06.2017)
Published in The Journal of biological chemistry (16.06.2017)
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Sirtuin 3 (SIRT3) Protein Regulates Long-chain Acyl-CoA Dehydrogenase by Deacetylating Conserved Lysines Near the Active Site
Bharathi, Sivakama S., Zhang, Yuxun, Mohsen, Al-Walid, Uppala, Radha, Balasubramani, Manimalha, Schreiber, Emanuel, Uechi, Guy, Beck, Megan E., Rardin, Matthew J., Vockley, Jerry, Verdin, Eric, Gibson, Bradford W., Hirschey, Matthew D., Goetzman, Eric S.
Published in The Journal of biological chemistry (22.11.2013)
Published in The Journal of biological chemistry (22.11.2013)
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Journal Article
Multiplexed, Scheduled, High-Resolution Parallel Reaction Monitoring on a Full Scan QqTOF Instrument with Integrated Data-Dependent and Targeted Mass Spectrometric Workflows
Schilling, Birgit, MacLean, Brendan, Held, Jason M, Sahu, Alexandria K, Rardin, Matthew J, Sorensen, Dylan J, Peters, Theodore, Wolfe, Alan J, Hunter, Christie L, MacCoss, Michael J, Gibson, Bradford W
Published in Analytical chemistry (Washington) (20.10.2015)
Published in Analytical chemistry (Washington) (20.10.2015)
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