ILT3 (LILRB4) Promotes the Immunosuppressive Function of Tumor-Educated Human Monocytic Myeloid-Derived Suppressor Cells
Singh, Latika, Muise, Eric S, Bhattacharya, Anannya, Grein, Jeff, Javaid, Sarah, Stivers, Peter, Zhang, Jun, Qu, Yujie, Joyce-Shaikh, Barbara, Loboda, Andrey, Zhang, Chunsheng, Meehl, Michael, Chiang, Derek Y, Ranganath, Sheila H, Rosenzweig, Michael, Brandish, Philip E
Published in Molecular cancer research (01.04.2021)
Published in Molecular cancer research (01.04.2021)
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Pharmacological inhibition of hematopoietic progenitor kinase 1 positively regulates T-cell function
Wang, Yun, Zhang, Kelvin, Georgiev, Peter, Wells, Steven, Xu, Haiyan, Lacey, Brian M, Xu, Zangwei, Laskey, Jason, Mcleod, Robbie, Methot, Joey L, Bittinger, Mark, Pasternak, Alexander, Ranganath, Sheila
Published in PloS one (03.12.2020)
Published in PloS one (03.12.2020)
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Combination of EP4 antagonist MF-766 and anti-PD-1 promotes anti-tumor efficacy by modulating both lymphocytes and myeloid cells
Wang, Yun, Cui, Long, Georgiev, Peter, Singh, Latika, Zheng, Yanyan, Yu, Ying, Grein, Jeff, Zhang, Chunsheng, Muise, Eric S., Sloman, David L., Ferguson, Heidi, Yu, Hongshi, Pierre, Cristina St, Dakle, Pranal J, Pucci, Vincenzo, Baker, James, Loboda, Andrey, Linn, Doug, Brynczka, Christopher, Wilson, Doug, Haines, Brian B, Long, Brian, Wnek, Richard, Sadekova, Svetlana, Rosenzweig, Michael, Haidle, Andrew, Han, Yongxin, Ranganath, Sheila H.
Published in Oncoimmunology (01.01.2021)
Published in Oncoimmunology (01.01.2021)
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Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotherapy Tool Compounds
Vara, Brandon A, Levi, Samuel M, Achab, Abdelghani, Candito, David A, Fradera, Xavier, Lesburg, Charles A, Kawamura, Shuhei, Lacey, Brian M, Lim, Jongwon, Methot, Joey L, Xu, Zangwei, Xu, Haiyan, Smith, Dustin M, Piesvaux, Jennifer A, Miller, J. Richard, Bittinger, Mark, Ranganath, Sheila H, Bennett, David J, DiMauro, Erin F, Pasternak, Alexander
Published in ACS medicinal chemistry letters (08.04.2021)
Published in ACS medicinal chemistry letters (08.04.2021)
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The AID antibody diversification enzyme is regulated by protein kinase A phosphorylation
Alt, Frederick W, Basu, Uttiya, Chaudhuri, Jayanta, Alpert, Craig, Dutt, Shilpee, Ranganath, Sheila, Li, Gang, Schrum, Jason Patrick, Manis, John P
Published in Nature (24.11.2005)
Published in Nature (24.11.2005)
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Inhibition of Th1 Development Mediated by GATA-3 through an IL-4-Independent Mechanism
Ouyang, Wenjun, Ranganath, Sheila H, Weindel, Kathryn, Bhattacharya, Deepta, Murphy, Theresa L, Sha, William C, Murphy, Kenneth M
Published in Immunity (Cambridge, Mass.) (01.11.1998)
Published in Immunity (Cambridge, Mass.) (01.11.1998)
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Combination of EP 4 antagonist MF-766 and anti-PD-1 promotes anti-tumor efficacy by modulating both lymphocytes and myeloid cells
Wang, Yun, Cui, Long, Georgiev, Peter, Singh, Latika, Zheng, Yanyan, Yu, Ying, Grein, Jeff, Zhang, Chunsheng, Muise, Eric S, Sloman, David L, Ferguson, Heidi, Yu, Hongshi, Pierre, Cristina St, Dakle, Pranal J, Pucci, Vincenzo, Baker, James, Loboda, Andrey, Linn, Doug, Brynczka, Christopher, Wilson, Doug, Haines, Brian B, Long, Brian, Wnek, Richard, Sadekova, Svetlana, Rosenzweig, Michael, Haidle, Andrew, Han, Yongxin, Ranganath, Sheila H
Published in Oncoimmunology (18.03.2021)
Published in Oncoimmunology (18.03.2021)
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1378 Discovery and characterization of PM-4321, a selective inhibitor of the aryl hydrocarbon receptor (AHR) with anti-tumor immunomodulatory effects
Ramani, Kritika, Wrocklage, Christopher, Bai, Ming, Bosco, Anna Nicole, Carter, Benjamin, Pruteanu-Malinici, Iulian, Perales, Lizeth, Dworakowski, Wojciech, Eustace, Brenda K, Yi, Kun Don, Sinclair, Charles, Kumar, Seema, Abbinanti, Matthew, Bartolozzi, Alessandra, Proudfoot, John Robert, Briggs, Timothy, Taylor, John Steven, Salter-Cid, Luisa, Ranganath, Sheila
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Discovery and Characterization of a Potent Interleukin-6 Binding Peptide with Neutralizing Activity In Vivo
Ranganath, Sheila, Bhandari, Ashok, Avitahl-Curtis, Nicole, McMahon, Jaimee, Wachtel, Derek, Zhang, Jenny, Leitheiser, Christopher, Bernier, Sylvie G, Liu, Guang, Tran, Tran T, Celino, Herodion, Tobin, Jenny, Jung, Joon, Zhao, Hong, Glen, Katie E, Graul, Chris, Griffin, Aliesha, Schairer, Wayne C, Higgins, Carolyn, Reza, Tammi L, Mowe, Eva, Rivers, Sam, Scott, Sonya, Monreal, Alex, Shea, Courtney, Bourne, Greg, Coons, Casey, Smith, Adaline, Tang, Kim, Mandyam, Ramya A, Masferrer, Jaime, Liu, David, Patel, Dinesh V, Fretzen, Angelika, Murphy, Craig A, Milne, G Todd, Smythe, Mark L, Carlson, Kenneth E
Published in PloS one (10.11.2015)
Published in PloS one (10.11.2015)
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Cutting Edge: GATA-3-Dependent Enhancer Activity in IL-4 Gene Regulation
Ranganath, Sheila, Ouyang, Wenjun, Bhattarcharya, Deepta, Sha, William C, Grupe, Andrew, Peltz, Gary, Murphy, Kenneth M
Published in The Journal of immunology (1950) (15.10.1998)
Published in The Journal of immunology (1950) (15.10.1998)
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Restriction of Endogenous T Cell Antigen Receptor β Rearrangements to Vβ14 through Selective Recombination Signal Sequence Modifications
Wu, Cherry, Ranganath, Sheila, Gleason, Megan, Woodman, Barbara B., Borjeson, Tiffany M., Alt, Frederick W., Bassing, Craig H.
Published in Proceedings of the National Academy of Sciences - PNAS (06.03.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (06.03.2007)
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Immune System Dysfunction and Autoimmune Disease in Mice Lacking Emk (Par-1) Protein Kinase
Hurov, Jonathan B., Stappenbeck, Thaddeus S., Zmasek, Christian M., White, Lynn S., Ranganath, Sheila H., Russell, John H., Chan, Andrew C., Murphy, Kenneth M., Piwnica-Worms, Helen
Published in Molecular and Cellular Biology (01.05.2001)
Published in Molecular and Cellular Biology (01.05.2001)
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Pharmacological Characterization of IW-1973, a Novel Soluble Guanylate Cyclase Stimulator with Extensive Tissue Distribution, Antihypertensive, Anti-Inflammatory, and Antifibrotic Effects in Preclinical Models of Disease
Tobin, Jenny V, Zimmer, Daniel P, Shea, Courtney, Germano, Peter, Bernier, Sylvie G, Liu, Guang, Long, Kim, Miyashiro, Joy, Ranganath, Sheila, Jacobson, Sarah, Tang, Kim, Im, G-Yoon Jamie, Sheppeck, 2nd, James, Moore, Joel D, Sykes, Kristine, Wakefield, James, Sarno, Renee, Banijamali, Ali R, Profy, Albert T, Milne, G Todd, Currie, Mark G, Masferrer, Jaime L
Published in The Journal of pharmacology and experimental therapeutics (01.06.2018)
Published in The Journal of pharmacology and experimental therapeutics (01.06.2018)
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STimulator of INterferon Genes Agonism Accelerates Antitumor Activity in Poorly Immunogenic Tumors
Perera, Samanthi A, Kopinja, Johnny E, Ma, Yanhong, Muise, Eric S, Laskey, Jason, Chakravarthy, Kalyan, Chen, Yiping, Cui, Long, Presland, Jeremy, Sathe, Manjiri, Javaid, Sarah, Minnihan, Ellen C, Ferguson, Heidi M, Piesvaux, Jennifer, Pan, Bo-Sheng, Zhao, Shuxia, Sharma, Sharad K, Woo, Hyun Chong, Pucci, Vincenzo, Knemeyer, Ian, Cemerski, Saso, Cumming, Jared, Trotter, B Wesley, Tse, Archie, Khilnani, Anuradha, Ranganath, Sheila, Long, Brian J, Bennett, David Jonathan, Addona, George H
Published in Molecular cancer therapeutics (01.02.2022)
Published in Molecular cancer therapeutics (01.02.2022)
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Abstract B30: Discovery and functional characterization of novel anti-PD-1 antibodies using ex vivo cell-based assays, single-cell immunoprofiling, and in vivo studies in humanized mice
Scheuplein, Felix, Ranganath, Sheila, McQuade, Thomas, Wang, Lei, Spaulding, Vikki, Vadde, Sri, Watkins-Yoon, Jennifer, Feng, Bin, Mehta, Shanu, Chiu, Maria Isabel, Nguyen, Cokey
Published in Cancer research (Chicago, Ill.) (01.08.2016)
Published in Cancer research (Chicago, Ill.) (01.08.2016)
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Abstract 4871: Two novel anti-PD-1 antibodies, 244C8 and 388D4, elicit in vivo antitumor efficacy in a lung PDX tumorgraft in immuno-humanized NSG mice
Scheuplein, Felix, Ranganath, Sheila, Feng, Bin, McQuade, Thomas, Wang, Lei, Spaulding, Vikki, Vadde, Sri, Mehta, Shanu, Chiu, Maria Isabel, Nguyen, Cokey
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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AID-initiated DNA lesions are differentially processed in distinct B cell populations (IRM8P.701)
Wang, Jing, Chen, Zhangguo, Ranganath, Sheila, Viboolsittiseri, Sawanee, Eder, Maxwell, Elos, Mihret, Chen, Xiaomi, Hansen, Erica
Published in The Journal of immunology (1950) (01.05.2014)
Published in The Journal of immunology (1950) (01.05.2014)
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Mo1886 Regulation of Linaclotide-Induced cGMP and Electrolyte Secretion by Multidrug Resistance-Associated Protein 4 (MRP4)
Tchernychev, Boris, Ge, Pei, Wachtel, Derek, Solinga, Robert, Kessler, Marco, Ranganath, Sheila, Hannig, Gerhard, Silos-Santiago, Inmaculada
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2015)
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2015)
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