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Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors
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A selective inhibitor reveals PI3Kγ dependence of T(H)17 cell differentiation
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Published in Nature chemical biology (29.04.2012)
Published in Nature chemical biology (29.04.2012)
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A selective inhibitor reveals PI3Kγ dependence of TH17 cell differentiation
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Chemoproteomics-Based Design of Potent LRRK2-Selective Lead Compounds That Attenuate Parkinson’s Disease-Related Toxicity in Human Neurons
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Published in ACS chemical biology (21.10.2011)
Published in ACS chemical biology (21.10.2011)
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SAR studies around a series of triazolopyridines as potent and selective PI3Kγ inhibitors
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Discovery of 5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-(tert-butyl)pyridine-3-sulfonamide (CZC24758), as a potent, orally bioavailable and selective inhibitor of PI3K for the treatment of inflammatory disease
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Published in Bioorganic & medicinal chemistry letters (21.06.1999)
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Abstract 1084: AI-aided drug development for disconnecting glioma tumor microtube networks
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