IL-1β production through the NLRP3 inflammasome by hepatic macrophages links hepatitis C virus infection with liver inflammation and disease
Negash, Amina A, Ramos, Hilario J, Crochet, Nanette, Lau, Daryl T Y, Doehle, Brian, Papic, Neven, Delker, Don A, Jo, Juandy, Bertoletti, Antonio, Hagedorn, Curt H, Gale, Jr, Michael
Published in PLoS pathogens (01.04.2013)
Published in PLoS pathogens (01.04.2013)
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Journal Article
The RIG-I-like Receptor LGP2 Controls CD8+ T Cell Survival and Fitness
Suthar, Mehul S., Ramos, Hilario J., Brassil, Margaret M., Netland, Jason, Chappell, Craig P., Blahnik, Gabriele, McMillan, Aimee, Diamond, Michael S., Clark, Edward A., Bevan, Michael J., Gale, Michael
Published in Immunity (Cambridge, Mass.) (24.08.2012)
Published in Immunity (Cambridge, Mass.) (24.08.2012)
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Journal Article
IL-1β signaling promotes CNS-intrinsic immune control of West Nile virus infection
Ramos, Hilario J, Lanteri, Marion C, Blahnik, Gabriele, Negash, Amina, Suthar, Mehul S, Brassil, Margaret M, Sodhi, Khushbu, Treuting, Piper M, Busch, Michael P, Norris, Philip J, Gale, Jr, Michael
Published in PLoS pathogens (01.11.2012)
Published in PLoS pathogens (01.11.2012)
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Journal Article
A systems biology approach reveals that tissue tropism to West Nile virus is regulated by antiviral genes and innate immune cellular processes
Suthar, Mehul S, Brassil, Margaret M, Blahnik, Gabriele, McMillan, Aimee, Ramos, Hilario J, Proll, Sean C, Belisle, Sarah E, Katze, Michael G, Gale, Jr, Michael
Published in PLoS pathogens (01.02.2013)
Published in PLoS pathogens (01.02.2013)
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Journal Article
Cutting edge: Type I IFN reverses human Th2 commitment and stability by suppressing GATA3
Huber, Jonathan P, Ramos, Hilario J, Gill, Michelle A, Farrar, J David
Published in The Journal of immunology (1950) (15.07.2010)
Published in The Journal of immunology (1950) (15.07.2010)
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Journal Article
Deficient IFN signaling by myeloid cells leads to MAVS-dependent virus-induced sepsis
Pinto, Amelia K, Ramos, Hilario J, Wu, Xiaobo, Aggarwal, Shilpa, Shrestha, Bimmi, Gorman, Matthew, Kim, Kristin Y, Suthar, Mehul S, Atkinson, John P, Gale, Jr, Michael, Diamond, Michael S
Published in PLoS pathogens (01.04.2014)
Published in PLoS pathogens (01.04.2014)
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Journal Article
Toll-like receptor 7 agonist GS-9620 induces prolonged inhibition of HBV via a type I interferon-dependent mechanism
Niu, Congrong, Li, Li, Daffis, Stephane, Lucifora, Julie, Bonnin, Marc, Maadadi, Sarah, Salas, Eduardo, Chu, Ruth, Ramos, Hilario, Livingston, Christine M., Beran, Rudolf K., Garg, Abhishek V., Balsitis, Scott, Durantel, David, Zoulim, Fabien, Delaney, William E., Fletcher, Simon P.
Published in Journal of hepatology (01.05.2018)
Published in Journal of hepatology (01.05.2018)
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Journal Article
Interleukin-1β Signaling in Dendritic Cells Induces Antiviral Interferon Responses
Aarreberg, Lauren D, Wilkins, Courtney, Ramos, Hilario J, Green, Richard, Davis, Michael A, Chow, Kwan, Gale, Jr, Michael
Published in mBio (20.03.2018)
Published in mBio (20.03.2018)
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Journal Article
The Smc5/6 Complex Restricts HBV when Localized to ND10 without Inducing an Innate Immune Response and Is Counteracted by the HBV X Protein Shortly after Infection
Niu, Congrong, Livingston, Christine M, Li, Li, Beran, Rudolf K, Daffis, Stephane, Ramakrishnan, Dhivya, Burdette, Dara, Peiser, Leanne, Salas, Eduardo, Ramos, Hilario, Yu, Mei, Cheng, Guofeng, Strubin, Michel, Delaney, IV, William E, Fletcher, Simon P
Published in PloS one (17.01.2017)
Published in PloS one (17.01.2017)
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Journal Article
The Bispecific Tumor Antigen-Conditional 4-1BB x 5T4 Agonist, ALG.APV-527, Mediates Strong T-Cell Activation and Potent Antitumor Activity in Preclinical Studies
Nelson, Michelle H, Fritzell, Sara, Miller, Robert, Werchau, Doreen, Van Citters, Danielle, Nilsson, Anneli, Misher, Lynda, Ljung, Lill, Bader, Robert, Deronic, Adnan, Chunyk, Allison G, Schultz, Lena, Varas, Laura A, Rose, Nadia, Håkansson, Maria, Gross, Jane, Furebring, Christina, Pavlik, Peter, Sundstedt, Anette, Veitonmäki, Niina, Ramos, Hilario J, Säll, Anna, Dahlman, Anna, Bienvenue, David, von Schantz, Laura, McMahan, Catherine J, Askmyr, Maria, Hernandez-Hoyos, Gabriela, Ellmark, Peter
Published in Molecular cancer therapeutics (03.01.2023)
Published in Molecular cancer therapeutics (03.01.2023)
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Journal Article
Pattern Recognition Receptor MDA5 Modulates CD8+ T Cell-Dependent Clearance of West Nile Virus from the Central Nervous System
Lazear, Helen M, Pinto, Amelia K, Ramos, Hilario J, Vick, Sarah C, Shrestha, Bimmi, Suthar, Mehul S, Gale, Jr, Michael, Diamond, Michael S
Published in Journal of Virology (01.11.2013)
Published in Journal of Virology (01.11.2013)
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Journal Article
795 APVO603: a dual 4-1BB and OX40 bispecific approach utilizing ADAPTIRTM technology designed to deliver a conditional T cell/NK response against solid tumors
Nelson, Michelle, Lucas, Ashly, Gottschalk, Rebecca, McMahan, Catherine, Gross, Jane, Ramos, Hilario
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Journal Article
796 ALG.APV-527: a 5T4 tumor directed bispecific approach utilizing ADAPTIRTM technology designed for conditional 4-1BB T cell/NK agonism against solid tumors
Nelson, Michelle, Sundstedt, Anette, Coaña, Yago Pico de, Lucas, Ashly, Nilsson, Anneli, Ljung, Lill, Chunyk, Allison, Schultz, Lena, McMahan, Catherine, Gross, Jane, Frizell, Sara, Ramos, Hilario, Ellmark, Peter
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Journal Article
IFN-alpha is not sufficient to drive Th1 development due to lack of stable T-bet expression
Ramos, Hilario J, Davis, Ann M, George, Thaddeus C, Farrar, J David
Published in Journal of Immunology (15.09.2007)
Published in Journal of Immunology (15.09.2007)
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Journal Article
CS04-8. IL-1 signaling and the NLRP3 Inflammasome are required for CNS-specific protective immunity against West Nile Virus
Ramos, Hilario J., Suthar, Mehul, Negash, Amina, Blahnick, Gabriele, Brassil, Maggie, Gale, Michael
Published in Cytokine (Philadelphia, Pa.) (01.10.2011)
Published in Cytokine (Philadelphia, Pa.) (01.10.2011)
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Journal Article