Novel dual LSD1/HDAC6 inhibitor for the treatment of cancer
Gajendran, Chandru, Tantry, Subramanyam Janardhan, M, Naveen Sadhu, Mohammed, Zainuddin, Dewang, Purushottam, Hallur, Mahanandeesha, Nair, Sreekala, Vaithilingam, Krishnakumar, Nagayya, Basavaprabhu, Rajagopal, Sridharan, Sivanandhan, Dhanalakshmi
Published in PloS one (03.01.2023)
Published in PloS one (03.01.2023)
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Journal Article
Alleviation of arthritis through prevention of neutrophil extracellular traps by an orally available inhibitor of protein arginine deiminase 4
Gajendran, Chandru, Fukui, Shoichi, Sadhu, Naveen M., Zainuddin, Mohammed, Rajagopal, Sridharan, Gosu, Ramachandraiah, Gutch, Sarah, Fukui, Saeko, Sheehy, Casey E., Chu, Long, Vishwakarma, Santosh, Jeyaraj, D. A., Hallur, Gurulingappa, Wagner, Denisa D., Sivanandhan, Dhanalakshmi
Published in Scientific reports (23.02.2023)
Published in Scientific reports (23.02.2023)
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Journal Article
Novel Inhibitors of Nicotinamide- N -Methyltransferase for the Treatment of Metabolic Disorders
Kannt, Aimo, Rajagopal, Sridharan, Hallur, Mahanandeesha S, Swamy, Indu, Kristam, Rajendra, Dhakshinamoorthy, Saravanakumar, Czech, Joerg, Zech, Gernot, Schreuder, Herman, Ruf, Sven
Published in Molecules (Basel, Switzerland) (13.02.2021)
Published in Molecules (Basel, Switzerland) (13.02.2021)
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Journal Article
A small molecule inhibitor of Nicotinamide N-methyltransferase for the treatment of metabolic disorders
Kannt, Aimo, Rajagopal, Sridharan, Kadnur, Sanjay Venkatachalapathi, Suresh, Juluri, Bhamidipati, Ravi Kanth, Swaminathan, Srinivasan, Hallur, Mahanandeesha Siddappa, Kristam, Rajendra, Elvert, Ralf, Czech, Jörg, Pfenninger, Anja, Rudolph, Christine, Schreuder, Herman, Chandrasekar, Devaraj Venkatapura, Mane, Vishal Subhash, Birudukota, Swarnakumari, Shaik, Shama, Zope, Bharat Ravindra, Burri, Raghunadha Reddy, Anand, Niranjan Naranapura, Thakur, Manish Kumar, Singh, Manvi, Parveen, Reejuana, Kandan, Saravanan, Mullangi, Ramesh, Yura, Takeshi, Gosu, Ramachandraiah, Ruf, Sven, Dhakshinamoorthy, Saravanakumar
Published in Scientific reports (26.02.2018)
Published in Scientific reports (26.02.2018)
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Journal Article
Novel tricyclic small molecule inhibitors of Nicotinamide N-methyltransferase for the treatment of metabolic disorders
Ruf, Sven, Rajagopal, Sridharan, Kadnur, Sanjay Venkatachalapathi, Hallur, Mahanandeesha S., Rani, Shilpa, Kristam, Rajendra, Swaminathan, Srinivasan, Zope, Bharat Ravindra, Gondrala, Pavan Kumar, Swamy, Indu, Putta, V. P. Rama Kishore, Kandan, Saravanan, Zech, Gernot, Schreuder, Herman, Rudolph, Christine, Elvert, Ralf, Czech, Joerg, Birudukota, Swarnakumari, Siddiqui, M. Amir, Anand, Niranjan Naranapura, Mane, Vishal Subhash, Dittakavi, Sreekanth, Suresh, Juluri, Gosu, Ramachandraiah, Ramesh, Mullangi, Yura, Takeshi, Dhakshinamoorthy, Saravanakumar, Kannt, Aimo
Published in Scientific reports (14.09.2022)
Published in Scientific reports (14.09.2022)
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Journal Article
Novel nicotinamide analog as inhibitor of nicotinamide N-methyltransferase
Ruf, Sven, Hallur, Mahanandeesha Siddappa, Anchan, Nisha K., Swamy, Indu N., Murugesan, Karthikai Raj, Sarkar, Sayantani, Narasimhulu, Lokesh Kananti, Putta, V.P. Rama Kishore, Shaik, Shama, Chandrasekar, Devaraj Venkatapura, Mane, Vishal Subhash, Kadnur, Sanjay Venkatachalapathi, Suresh, Juluri, Bhamidipati, Ravi Kanth, Singh, Manvi, Burri, Raghunadha Reddy, Kristam, Rajendra, Schreuder, Herman, Czech, Joerg, Rudolph, Christine, Marker, Alexander, Langer, Thomas, Mullangi, Ramesh, Yura, Takeshi, Gosu, Ramachandraiah, Kannt, Aimo, Dhakshinamoorthy, Saravanakumar, Rajagopal, Sridharan
Published in Bioorganic & medicinal chemistry letters (01.03.2018)
Published in Bioorganic & medicinal chemistry letters (01.03.2018)
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Journal Article
Discovery of adamantane based highly potent HDAC inhibitors
Gopalan, Balasubramanian, Ponpandian, Thanasekaran, Kachhadia, Virendra, Bharathimohan, Kuppusamy, Vignesh, Radhakrishnan, Sivasudar, Velaiah, Narayanan, Shridhar, Mandar, Bhonde, Praveen, Rajendran, Saranya, Nithyanandan, Rajagopal, Sriram, Rajagopal, Sridharan
Published in Bioorganic & medicinal chemistry letters (01.05.2013)
Published in Bioorganic & medicinal chemistry letters (01.05.2013)
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Journal Article
Validation of an LC–MS/MS Method for Simultaneous Detection of Five Selective KCNQ Channel Openers: ICA-27243, ML-213, PF-05020182, SF-0034 and Flupirtine in Mice Plasma and its Application to a Pharmacokinetic Study in Mice
Todmal, Umesh, Sulochana, Suresh P., Zainuddin, Mohd, Bhamidipati, Ravi Kanth, Samanta, Swapan Kumar, Hallur, Gurulingappa, Rajagopal, Sridharan, Rajagopal, Sriram, Mullangi, Ramesh
Published in Chromatographia (01.03.2018)
Published in Chromatographia (01.03.2018)
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Journal Article
An improved method of transcutaneous cisterna magna puncture for cerebrospinal fluid sampling in rats
Mahat, Mahamad Yunnus A., Fakrudeen Ali Ahamed, N., Chandrasekaran, S., Rajagopal, Sridharan, Narayanan, Shridhar, Surendran, Narayanan
Published in Journal of neuroscience methods (15.11.2012)
Published in Journal of neuroscience methods (15.11.2012)
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Journal Article
A Novel Selective Inhibitor JBI-589 Targets PAD4-Mediated Neutrophil Migration to Suppress Tumor Progression
Deng, Hui, Lin, Cindy, Garcia-Gerique, Laura, Fu, Shuyu, Cruz, Zachary, Bonner, Erin E, Rosenwasser, Matthew, Rajagopal, Sridharan, Sadhu, M Naveen, Gajendran, Chandru, Zainuddin, Mohd, Gosu, Ramachandraiah, Sivanandhan, Dhanalakshmi, Shelef, Miriam A, Nam, Brian, Vogl, Dan T, Gabrilovich, Dmitry I, Nefedova, Yulia
Published in Cancer research (Chicago, Ill.) (04.10.2022)
Published in Cancer research (Chicago, Ill.) (04.10.2022)
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Journal Article
Novel dual LSD1/HDAC6 inhibitors for the treatment of multiple myeloma
Naveen Sadhu, M, Sivanandhan, Dhanalakshmi, Gajendran, Chandru, Tantry, Subramanyam, Dewang, Purushottam, Murugan, Kannan, Chickamunivenkatappa, Srinatha, Zainuddin, Mohd, Nair, Sreekala, Vaithilingam, Krishnakumar, Rajagopal, Sridharan
Published in Bioorganic & medicinal chemistry letters (15.02.2021)
Published in Bioorganic & medicinal chemistry letters (15.02.2021)
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Journal Article
PD1/PD-L1 억제제로서의 화합물 및 이의 방법
MOHD ZAINUDDIN, SADHU NAVEEN, SIVANANDHAN DHANALAKSHMI, RAJAGOPAL SRIDHARAN
Year of Publication 31.01.2024
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Year of Publication 31.01.2024
Patent
Abstract 1756: JBI-802, novel dual inhibitor of LSD1-HDAC6 for treatment of cancer
Sivanandhan, Dhanalakshmi, Rajagopal, Sridharan, Nair, Sreekala, B, Basavaprabhu, Dhkar, Reshma, Viswakarma, Santosh, Siddiqui, Amir, Zainuddin, Mohd, G, Rudresh, Daram, Prashanthi, Mohire, Sunil, V, Krishnakumar
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Abstract 1128: Selective, novel, small molecule PRMT5 inhibitors for treatment of cancer
Sivanandhan, Dhanalakshmi, Rajagopal, Sridharan, M, Naveen Sadhu, Gajendran, Chandru, Vadivelu, Saravanan, Tamizharasan, Natarajan, Swamy, Indu N., Viswakarma, Santhosh, Siddiqui, Amir, wahid, Saif, Zainuddin, Mohammed, G, Rudresh, Daram, Prashanthi, Gosu, Ramchandraiah, Tiagaraj, Dinesh, Garapaty, Shivani, Nair, Sreekala, Kapoor, Namratha
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Abstract 1630: Novel, small molecule inhibitors of PD-L1/PD-1 interaction
Sivanandhan, Dhanalakshmi, Rajagopal, Sridharan, M, Naveen Sadhu, Gajendran, Chandru, venkateshappa, Chandregowda, Reddy, Muralidhar, Kishore, Pendyala Satya, Deshpande, Pratima, kannan, Sundarajan, Sahareen, Tabassum, Viswakarma, Santhosh, Siddiqui, Amir, Zainuddin, Mohammed, G, Rudresh, Daram, Prashanthi, Gosu, Ramchandraiah, Devi, Rashmi Rekha
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Novel, small molecule inhibitors of PD-1/PD-L1 pathway
Rastelli, Luca, Rajagopal, Sridharan, Gajendran, Chandru, Sadhu, Naveen M., Mohd, Zainuddin, Gosu, Ramachandraiah, Friedmann-Morvinski, Dinorah, Kandan, Saravanan, Birudukota, Swarnakumari, S, Srinivasan, V, Krishnakumar, Wahid, Saif, Siddiqui, Amir, Viswakarma, Santosh, Narayan, Ashwini, G, Rudresh, Mullurwar, Sadanand R., Sher, Divsha, Mansur, Shahar, Sivanandhan, Dhanalakshmi
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
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Journal Article
Novel Dual Inhibitor of LSD1-HDAC6/8 for Treatment of Cancer
S, Dhanalakshmi, Rajagopal, Sridharan, Sadhu, Naveen, G, Chandru, Siddiqui, Amir, Wahid, Saif, Prabhu, Basava, KS, Neha, Nair, Sreekala, G, Rudresh, Daram, Prasanthi, Zainuddin, Mohd, Tantry, Subramanyam J, Thiagaraj, Dinesh, V, Krishnakumar, Vishwakarma, Santosh
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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Journal Article