Identification of Monosaccharide Derivatives as Potent, Selective, and Orally Bioavailable Inhibitors of Human and Mouse Galectin‑3
Liu, Chunjian, Jalagam, Prasada Rao, Feng, Jianxin, Wang, Wei, Raja, Thiruvenkadam, Sura, Mallikarjuna Reddy, Manepalli, Raju K. V. L. P., Aliphedi, Bheema Reddy, Medavarapu, Santosh, Nair, Satheesh K., Muthalagu, Vetrichelvan, Natesan, Ramesh, Gupta, Anuradha, Beno, Brett, Panda, Manoranjan, Ghosh, Kaushik, Shukla, Jinal Kaushikkumar, Sale, Harinath, Haldar, Priyanka, Kalidindi, Narasimharaju, Shah, Devang, Patel, Dipal, Mathur, Arvind, Ellsworth, Bruce A., Cheng, Dong, Regueiro-Ren, Alicia
Published in Journal of medicinal chemistry (25.08.2022)
Published in Journal of medicinal chemistry (25.08.2022)
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Identification of benzothiazole derived monosaccharides as potent, selective, and orally bioavailable inhibitors of human and mouse galectin-3; a rare example of using a S···O binding interaction for drug design
Liu, Chunjian, Wang, Wei, Feng, Jianxin, Beno, Brett, Raja, Thiruvenkadam, Swidorski, Jacob, Manepalli, Raju K.V.L.P., Vetrichelvan, Muthalagu, Rao Jalagam, Prasada, Nair, Satheesh K., Gupta, Anuradha, Panda, Manoranjan, Ghosh, Kaushik, Kaushikkumar Shukla, Jinal, Sale, Harinath, Shah, Devang, Singh Gautam, Shashyendra, Patel, Dipal, Mathur, Arvind, Ellsworth, Bruce A., Cheng, Dong, Regueiro-Ren, Alicia
Published in Bioorganic & medicinal chemistry (01.03.2024)
Published in Bioorganic & medicinal chemistry (01.03.2024)
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BMS-871: A novel orally active pan-Notch inhibitor as an anticancer agent
Shan, Weifang, Balog, Aaron, Quesnelle, Claude, Gill, Patrice, Han, Wen-Ching, Norris, Derek, Mandal, Sunilkumar, Thiruvenkadam, Raja, Gona, Kiran Babu, Thiyagarajan, Kamalraj, Kandula, Sathiah, McGlinchey, Kelly, Menard, Krista, Wen, Mei-Li, Rose, Anne, White, Ronald, Guarino, Victor, Shen, Ding Ren, Cvijic, Mary Ellen, Ranasinghe, Asoka, Dai, Jun, Zhang, Yingru, Wu, Dauh-Rurng, Mathur, Arvind, Rampulla, Richard, Trainor, George, Hunt, John T., Vite, Gregory D., Westhouse, Richard, Lee, Francis Y., Gavai, Ashvinikumar V.
Published in Bioorganic & medicinal chemistry letters (01.05.2015)
Published in Bioorganic & medicinal chemistry letters (01.05.2015)
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DGK 억제제 및 체크포인트 길항제의 조합물
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Year of Publication 25.08.2022
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Year of Publication 25.08.2022
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T 세포 활성화제로서 유용한 치환된 나프티리디논 화합물
DING MIN, CHUPAK LOUIS S, TOKARSKI JOHN S, REDDY KOTHA RATHNAKAR, ROY SAUMYA, TONUKUNURU GOPIKISHAN, KAMBLE MANJUNATHA NARAYANA RAO, VELAPARTHI UPENDER, WARRIER JAYAKUMAR SANKARA, DARNE CHETAN PADMAKAR, MARTIN SCOTT W, MCDONALD IVAR M, ZHENG XIAOFAN, DASGUPTA BIRESHWAR, MANNOORI RAJU, RAJA THIRUVENKADAM, JALAGAM PRASADA RAO, RAHAMAN HASIBUR, VELAIAH SIVASUDAR, GENTLES ROBERT G, OLSON RICHARD E, HUANG YAZHONG
Year of Publication 05.03.2021
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Year of Publication 05.03.2021
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SUBSTITUTED NAPHTHYRIDINONE COMPOUNDS USEFUL AS T CELL ACTIVATORS
Tokarski, John S, Jalagam, Prasada Rao, Chupak, Louis S, Dasgupta, Bireshwar, Velaparthi, Upender, Velaiah, Sivasudar, Martin, Scott W, Zheng, Xiaofan, Reddy, Kotha Rathnakar, Kamble, Manjunatha Narayana Rao, Olson, Richard E, Warrier, Jayakumar Sankara, Raja, Thiruvenkadam, Darne, Chetan Padmakar, Rahaman, Hasibur, McDonald, Ivar M, Ding, Min, Tonukunuru, Gopikishan, Huang, Yazhong, Roy, Saumya, Gentles, Robert G, Mannoori, Raju
Year of Publication 02.02.2024
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Year of Publication 02.02.2024
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SUBSTITUTED NAPHTHYRIDINONE COMPOUNDS USEFUL AS T CELL ACTIVATORS
GENTLES, Robert G, MCDONALD, Ivar M, VELAPARTHI, Upender, CHUPAK, Louis S, DARNE, Chetan Padmakar, REDDY, Kotha Rathnakar, TONUKUNURU, Gopikishan, ROY, Saumya, ZHENG, Xiaofan, OLSON, Richard E, MARTIN, Scott W, JALAGAM, Prasada Rao, RAHAMAN, Hasibur, VELAIAH, Sivasudar, MANNOORI, Raju, TOKARSKI, John S, HUANG, Yazhong, RAJA, Thiruvenkadam, WARRIER, Jayakumar Sankara, KAMBLE, Manjunatha Narayana Rao, DING, Min, DASGUPTA, Bireshwar
Year of Publication 01.11.2023
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Year of Publication 01.11.2023
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SUBSTITUTED NAPHTHYRIDINONE COMPOUNDS USEFUL AS T CELL ACTIVATORS
RAHAMAN, HASIBUR, WARRIER, JAYAKUMAR, SANKARA, OLSON, RICHARD, E, JALAGAM, PRASADA, RAO, MANNOORI, RAJU, ROY, SAUMYA, MARTIN, SCOTT, W, MCDONALD, IVAR, M, DASGUPTA, BIRESHWAR, DING, MIN, HUANG, YAZHONG, CHUPAK, LOUIS, S, GENTLES, ROBERT, G, REDDY, KOTHA RATHNAKAR, DARNE, CHETAN, PADMAKAR, TONUKUNURU, GOPIKISHAN, VELAIAH, SIVASUDAR, VELAPARTHI, UPENDER, KAMBLE, MANJUNATHA, NARAYANA, RAO, TOKARSKI, JOHN, S, ZHENG, XIAOFAN, RAJA, THIRUVENKADAM
Year of Publication 31.10.2023
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Year of Publication 31.10.2023
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SUBSTITUTED NAPHTHYRIDINONE COMPOUNDS USEFUL AS T CELL ACTIVATORS
HUANG Yazhong, MANNOORI Raju, VELAPARTHI Upender, DARNE Chetan Padmakar, KAMBLE Manjunatha Narayana Rao, VELAIAH Sivasudar, CHUPAK Louis S, MARTIN Scott W, DASGUPTA Bireshwar, TOKARSKI John S, TONUKUNURU Gopikishan, ZHENG Xiaofan, RAJA Thiruvenkadam, ROY Saumya, DING Min, RAHAMAN Hasibur, WARRIER Jayakumar Sankara, OLSON Richard E, GENTLES Robert G, JALAGAM Prasada Rao, MCDONALD Ivar M, REDDY Kotha Rathnakar
Year of Publication 30.10.2023
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Year of Publication 30.10.2023
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SUBSTITUEREDE NAPHTHYRIDINONFORBINDELSER, DER ER ANVENDELIGE SOM T-CELLEAKTIVATORER
GENTLES, Robert G, MCDONALD, Ivar M, VELAPARTHI, Upender, CHUPAK, Louis S, DARNE, Chetan Padmakar, REDDY, Kotha Rathnakar, TONUKUNURU, Gopikishan, ROY, Saumya, ZHENG, Xiaofan, OLSON, Richard E, MARTIN, Scott W, JALAGAM, Prasada Rao, RAHAMAN, Hasibur, VELAIAH, Sivasudar, MANNOORI, Raju, TOKARSKI, John S, HUANG, Yazhong, RAJA, Thiruvenkadam, WARRIER, Jayakumar Sankara, KAMBLE, Manjunatha Narayana Rao, DING, Min, DASGUPTA, Bireshwar
Year of Publication 30.10.2023
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Year of Publication 30.10.2023
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SUBSTITUTED NAPHTHYRIDINONE COMPOUNDS USEFUL AS T CELL ACTIVATORS
GENTLES, Robert G, MCDONALD, Ivar M, VELAPARTHI, Upender, CHUPAK, Louis S, DARNE, Chetan Padmakar, REDDY, Kotha Rathnakar, TONUKUNURU, Gopikishan, ROY, Saumya, ZHENG, Xiaofan, OLSON, Richard E, MARTIN, Scott W, JALAGAM, Prasada Rao, RAHAMAN, Hasibur, VELAIAH, Sivasudar, MANNOORI, Raju, TOKARSKI, John S, HUANG, Yazhong, RAJA, Thiruvenkadam, WARRIER, Jayakumar Sankara, KAMBLE, Manjunatha Narayana Rao, DING, Min, DASGUPTA, Bireshwar
Year of Publication 10.10.2023
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Year of Publication 10.10.2023
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SUBSTITUTED NAPHTHYRIDINONE COMPOUNDS USEFUL AS T CELL ACTIVATORS
GENTLES, Robert G, MCDONALD, Ivar M, VELAPARTHI, Upender, CHUPAK, Louis S, DARNE, Chetan Padmakar, REDDY, Kotha Rathnakar, TONUKUNURU, Gopikishan, ROY, Saumya, ZHENG, Xiaofan, OLSON, Richard E, MARTIN, Scott W, JALAGAM, Prasada Rao, RAHAMAN, Hasibur, VELAIAH, Sivasudar, MANNOORI, Raju, TOKARSKI, John S, HUANG, Yazhong, RAJA, Thiruvenkadam, WARRIER, Jayakumar Sankara, KAMBLE, Manjunatha Narayana Rao, DING, Min, DASGUPTA, Bireshwar
Year of Publication 22.09.2023
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Year of Publication 22.09.2023
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SUBSTITUTED NAPHTHYRIDINONE COMPOUNDS USEFUL AS T CELL ACTIVATORS
KAMBLE, MANJUNATHA NARAYANA RAO, RAHAMAN, HASIBUR, OLSON, RICHARD E, MANNOORI, RAJU, GENTLES, ROBERT G, MARTIN, SCOTT W, ROY, SAUMYA, WARRIER, JAYAKUMAR SANKARA, DASGUPTA, BIRESHWAR, DING, MIN, JALAGAM, PRASADA RAO, CHUPAK, LOUIS S, HUANG, YAZHONG, REDDY, KOTHA RATHNAKAR, TONUKUNURU, GOPIKISHAN, VELAIAH, SIVASUDAR, TOKARSKI, JOHN S, MCDONALD, IVAR M, VELAPARTHI, UPENDER, DARNE, CHETAN PADMAKAR, ZHENG, XIAOFAN, RAJA, THIRUVENKADAM
Year of Publication 11.09.2023
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Year of Publication 11.09.2023
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SUBSTITUTED NAPHTHYRIDINONE COMPOUNDS USEFUL AS T CELL ACTIVATORS
GENTLES, Robert G, MCDONALD, Ivar M, VELAPARTHI, Upender, CHUPAK, Louis S, DARNE, Chetan Padmakar, REDDY, Kotha Rathnakar, TONUKUNURU, Gopikishan, ROY, Saumya, ZHENG, Xiaofan, OLSON, Richard E, MARTIN, Scott W, JALAGAM, Prasada Rao, RAHAMAN, Hasibur, VELAIAH, Sivasudar, MANNOORI, Raju, TOKARSKI, John S, HUANG, Yazhong, RAJA, Thiruvenkadam, WARRIER, Jayakumar Sankara, KAMBLE, Manjunatha Narayana Rao, DING, Min, DASGUPTA, Bireshwar
Year of Publication 02.08.2023
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Year of Publication 02.08.2023
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Substituted naphthyridinone compounds useful as T cell activators
Tokarski, John S, Jalagam, Prasada Rao, Chupak, Louis S, Dasgupta, Bireshwar, Velaparthi, Upender, Velaiah, Sivasudar, Martin, Scott W, Zheng, Xiaofan, Reddy, Kotha Rathnakar, Kamble, Manjunatha Narayana Rao, Olson, Richard E, Warrier, Jayakumar Sankara, Raja, Thiruvenkadam, Darne, Chetan Padmakar, Rahaman, Hasibur, McDonald, Ivar M, Ding, Min, Tonukunuru, Gopikishan, Huang, Yazhong, Roy, Saumya, Gentles, Robert G, Mannoori, Raju
Year of Publication 01.08.2023
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Year of Publication 01.08.2023
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Substituted naphthyridinone compounds useful as t cell activators
HUANG Yazhong, MANNOORI Raju, VELAPARTHI Upender, DARNE Chetan Padmakar, KAMBLE Manjunatha Narayana Rao, VELAIAH Sivasudar, CHUPAK Louis S, MARTIN Scott W, DASGUPTA Bireshwar, TOKARSKI John S, TONUKUNURU Gopikishan, ZHENG Xiaofan, RAJA Thiruvenkadam, ROY Saumya, DING Min, RAHAMAN Hasibur, WARRIER Jayakumar Sankara, OLSON Richard E, GENTLES Robert G, JALAGAM Prasada Rao, MCDONALD Ivar M, REDDY Kotha Rathnakar
Year of Publication 01.07.2023
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Year of Publication 01.07.2023
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COMBINATIONS OF DGK INHIBITORS AND CHECKPOINT ANTAGONISTS
BENC, Joseph L, MCDONALD, Ivar M, VELAPARTHI, Upender, TONUKUNURU, Gopikishan, ROY, Saumya, MARTIN, Scott W, JALAGAM, Prasada Rao, WICHROSKI, Michael, VELAIAH, Sivasudar, RAJA, Thiruvenkadam, WEE, Susan, WANG, Xinyu, GRUNENFELDER, Denise, DING, Min, DARNE, Chatan P, GENTLES, Robert G, CHUPAK, Louis S, REDDY, Kotha Rathnakar, ZHENG, Xiaofan, OLSON, Richard E, RAHAMAN, Haslbur, TOKARSKI, John S, MANNOORI, Raju, HUANG, Yazhong, WARRIER, Jayakumar Sankara, KAMBLE, Manjunatha Narayana Rao, DASGUPTA, Bireshwar
Year of Publication 23.03.2023
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Year of Publication 23.03.2023
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Substituted naphthyridinone compounds useful as t cell activators
HUANG Yazhong, MANNOORI Raju, VELAPARTHI Upender, DARNE Chetan Padmakar, KAMBLE Manjunatha Narayana Rao, VELAIAH Sivasudar, CHUPAK Louis S, MARTIN Scott W, DASGUPTA Bireshwar, TOKARSKI John S, TONUKUNURU Gopikishan, ZHENG Xiaofan, RAJA Thiruvenkadam, ROY Saumya, DING Min, RAHAMAN Hasibur, WARRIER Jayakumar Sankara, OLSON Richard E, GENTLES Robert G, JALAGAM Prasada Rao, MCDONALD Ivar M, REDDY Kotha Rathnakar
Year of Publication 01.03.2023
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Year of Publication 01.03.2023
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SUBSTITUTED NAPHTHYRIDINONE COMPOUNDS USEFUL AS T CELL ACTIVATORS
Tokarski, John S, Jalagam, Prasada Rao, Chupak, Louis S, Dasgupta, Bireshwar, Velaparthi, Upender, Velaiah, Sivasudar, Martin, Scott W, Zheng, Xiaofan, Reddy, Kotha Rathnakar, Kamble, Manjunatha Narayana Rao, Olson, Richard E, Warrier, Jayakumar Sankara, Raja, Thiruvenkadam, Darne, Chetan Padmakar, Rahaman, Hasibur, McDonald, Ivar M, Ding, Min, Tonukunuru, Gopikishan, Huang, Yazhong, Roy, Saumya, Gentles, Robert G, Mannoori, Raju
Year of Publication 13.10.2022
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Year of Publication 13.10.2022
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SUBSTITUTED NAPHTHYRIDINONE COMPOUNDS USEFUL AS T CELL ACTIVATORS
GENTLES, Robert G, MCDONALD, Ivar M, VELAPARTHI, Upender, CHUPAK, Louis S, DARNE, Chetan Padmakar, REDDY, Kotha Rathnakar, TONUKUNURU, Gopikishan, ROY, Saumya, ZHENG, Xiaofan, OLSON, Richard E, MARTIN, Scott W, JALAGAM, Prasada Rao, RAHAMAN, Hasibur, VELAIAH, Sivasudar, MANNOORI, Raju, TOKARSKI, John S, HUANG, Yazhong, RAJA, Thiruvenkadam, WARRIER, Jayakumar Sankara, KAMBLE, Manjunatha Narayana Rao, DING, Min, DASGUPTA, Bireshwar
Year of Publication 27.07.2022
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Year of Publication 27.07.2022
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