Opportunities in somatostatin research: biological, chemical and therapeutic aspects
Weckbecker, Gisbert, Lewis, Ian, Albert, Rainer, Schmid, Herbert A, Hoyer, Daniel, Bruns, Christian
Published in Nature reviews. Drug discovery (01.12.2003)
Published in Nature reviews. Drug discovery (01.12.2003)
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The Immune Modulator FTY720 Targets Sphingosine 1-Phosphate Receptors
Brinkmann, Volker, Davis, Michael D, Heise, Christopher E, Albert, Rainer, Cottens, Sylvain, Hof, Robert, Bruns, Christian, Prieschl, Eva, Baumruker, Thomas, Hiestand, Peter, Foster, Carolyn A, Zollinger, Markus, Lynch, Kevin R
Published in The Journal of biological chemistry (14.06.2002)
Published in The Journal of biological chemistry (14.06.2002)
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Discovery of 3-(1H-Indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5-dione (AEB071), a Potent and Selective Inhibitor of Protein Kinase C Isotypes
Wagner, Jürgen, von Matt, Peter, Sedrani, Richard, Albert, Rainer, Cooke, Nigel, Ehrhardt, Claus, Geiser, Martin, Rummel, Gabriele, Stark, Wilhelm, Strauss, Andre, Cowan-Jacob, Sandra W, Beerli, Christian, Weckbecker, Gisbert, Evenou, Jean-Pierre, Zenke, Gerhard, Cottens, Sylvain
Published in Journal of medicinal chemistry (22.10.2009)
Published in Journal of medicinal chemistry (22.10.2009)
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Novel Immunomodulator FTY720 Is Phosphorylated in Rats and Humans To Form a Single Stereoisomer. Identification, Chemical Proof, and Biological Characterization of the Biologically Active Species and Its Enantiomer
Albert, Rainer, Hinterding, Klaus, Brinkmann, Volker, Guerini, Danilo, Müller-Hartwieg, Constanze, Knecht, Helmut, Simeon, Corinne, Streiff, Markus, Wagner, Trixie, Welzenbach, Karl, Zécri, Frédéric, Zollinger, Markus, Cooke, Nigel, Francotte, Eric
Published in Journal of medicinal chemistry (11.08.2005)
Published in Journal of medicinal chemistry (11.08.2005)
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FTY720 induces apoptosis in multiple myeloma cells and overcomes drug resistance
YASUI, Hiroshi, HIDESHIMA, Teru, CATLEY, Laurence, MITSIADES, Constantine S, RICHARDSON, Paul G, ALBERT, Rainer, BRINKMANN, Volker, CHAUHAN, Dharminder, ANDERSON, Kenneth C, RAJE, Noopur, ROCCARO, Aldo M, SHIRAISHI, Norihiko, KUMAR, Shaji, HAMASAKI, Makoto, ISHITSUKA, Kenji, TAI, Yu-Tzu, PODAR, Klaus
Published in Cancer research (Chicago, Ill.) (15.08.2005)
Published in Cancer research (Chicago, Ill.) (15.08.2005)
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Opportunities in somatostatin research: biological, chemical and therapeutic aspects
Gisbert, Weckbecker, Ian, Lewis, Rainer, Albert, Herbert A, Schmid, Daniel, Hoyer, Christian, Bruns
Published in Nature reviews. Drug discovery (01.12.2005)
Published in Nature reviews. Drug discovery (01.12.2005)
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Web Service Discovery and Composition for Virtual Enterprises
Dorn, Jürgen, Hrastnik, Peter, Rainer, Albert
Published in International journal of web services research (01.01.2007)
Published in International journal of web services research (01.01.2007)
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Direct synthesis of [DOTA-DPhe 1]-octreotide and [DOTA-DPhe 1, Tyr 3]-octreotide (SMT487): Two conjugates for systemic delivery of radiotherapeutical nuclides to somatostatin receptor positive tumors in man
Albert, Rainer, Smith-Jones, Peter, Stolz, Barbara, Simeon, Corinne, Knecht, Hellmut, Bruns, Christian, Pless, Janos
Published in Bioorganic & medicinal chemistry letters (19.05.1998)
Published in Bioorganic & medicinal chemistry letters (19.05.1998)
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Episodic recognition memory based on incidental learning of visual associations is largely preserved compared to recall in amnestic mild cognitive impairment and mild Alzheimer's disease
Meyer, Sascha Rainer Albert, Boelaarts, Leo, Lindeboom, Jaap, De Jonghe, Jos F. M., Ponds, Rudolf
Published in Applied neuropsychology. Adult (02.01.2022)
Published in Applied neuropsychology. Adult (02.01.2022)
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The superior therapeutic properties of SOM230 originate from unique structural elements
Lewis, Albert, R, Bauer, W, Chandramouli, N, Pless, J, Oberer, L, Bovermann, G, van der Hoek, J, Boerlin, Lamberts, SWJ, Schmid, HA, Weckbecker, G, Bruns, C
Published in Chimia (01.04.2004)
Published in Chimia (01.04.2004)
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The Sphingosine 1-Phosphate Receptor Agonist FTY720 Differentially Affects the Sequestration of CD4+/CD25+ T-Regulatory Cells and Enhances Their Functional Activity
Sawicka, Elzbieta, Dubois, Gerald, Jarai, Gabor, Edwards, Matthew, Thomas, Matthew, Nicholls, Andy, Albert, Rainer, Newson, Catherine, Brinkmann, Volker, Walker, Christoph
Published in The Journal of immunology (1950) (15.12.2005)
Published in The Journal of immunology (1950) (15.12.2005)
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Structure–Activity Relationship and Pharmacokinetic Studies of Sotrastaurin (AEB071), a Promising Novel Medicine for Prevention of Graft Rejection and Treatment of Psoriasis
Wagner, Jürgen, von Matt, Peter, Faller, Bernard, Cooke, Nigel G, Albert, Rainer, Sedrani, Richard, Wiegand, Hansjörg, Jean, Christian, Beerli, Christian, Weckbecker, Gisbert, Evenou, Jean-Pierre, Zenke, Gerhard, Cottens, Sylvain
Published in Journal of medicinal chemistry (08.09.2011)
Published in Journal of medicinal chemistry (08.09.2011)
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A Novel Somatostatin Mimic with Broad Somatotropin Release Inhibitory Factor Receptor Binding and Superior Therapeutic Potential
Lewis, Ian, Bauer, Wilfried, Albert, Rainer, Chandramouli, Nagarajan, Pless, Janos, Weckbecker, Gisbert, Bruns, Christian
Published in Journal of medicinal chemistry (05.06.2003)
Published in Journal of medicinal chemistry (05.06.2003)
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Pyrazole derived from (+)-3-carene; a novel potent, selective scaffold for sphingosine-1-phosphate (S1P 1) receptor agonists
Zécri, Frédéric J., Albert, Rainer, Landrum, Gregory, Hinterding, Klaus, Cooke, Nigel G., Guerini, Danilo, Streiff, Markus, Bruns, Christian, Nuesslein-Hildesheim, Barbara
Published in Bioorganic & medicinal chemistry letters (2010)
Published in Bioorganic & medicinal chemistry letters (2010)
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1,4-Diazepane-2,5-diones as novel inhibitors of LFA-1
Wattanasin, Sompong, Kallen, Joerg, Myers, Stewart, Guo, Qin, Sabio, Michael, Ehrhardt, Claus, Albert, Rainer, Hommel, Ulrich, Weckbecker, Gisbert, Welzenbach, Karl, Weitz-Schmidt, Gabriele
Published in Bioorganic & medicinal chemistry letters (15.02.2005)
Published in Bioorganic & medicinal chemistry letters (15.02.2005)
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