Extensive somatic L1 retrotransposition in colorectal tumors
Solyom, Szilvia, Ewing, Adam D, Rahrmann, Eric P, Doucet, Tara, Nelson, Heather H, Burns, Michael B, Harris, Reuben S, Sigmon, David F, Casella, Alex, Erlanger, Bracha, Wheelan, Sarah, Upton, Kyle R, Shukla, Ruchi, Faulkner, Geoffrey J, Largaespada, David A, Kazazian, Jr, Haig H
Published in Genome research (01.12.2012)
Published in Genome research (01.12.2012)
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Journal Article
Forward genetic screen for malignant peripheral nerve sheath tumor formation identifies new genes and pathways driving tumorigenesis
Rahrmann, Eric P, Watson, Adrienne L, Keng, Vincent W, Choi, Kwangmin, Moriarity, Branden S, Beckmann, Dominic A, Wolf, Natalie K, Sarver, Aaron, Collins, Margaret H, Moertel, Christopher L, Wallace, Margaret R, Gel, Bernat, Serra, Eduard, Ratner, Nancy, Largaespada, David A
Published in Nature genetics (01.07.2013)
Published in Nature genetics (01.07.2013)
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Journal Article
PLX3397 treatment inhibits constitutive CSF1R-induced oncogenic ERK signaling, reduces tumor growth, and metastatic burden in osteosarcoma
Smeester, Branden A., Slipek, Nicholas J., Pomeroy, Emily J., Laoharawee, Kanut, Osum, Sara H., Larsson, Alex T., Williams, Kyle B., Stratton, Natalie, Yamamoto, Kenta, Peterson, Joseph J., Rathe, Susan K., Mills, Lauren J., Hudson, Wendy A., Crosby, Margaret R., Wang, Minjing, Rahrmann, Eric P., Moriarity, Branden S., Largaespada, David A.
Published in Bone (New York, N.Y.) (01.07.2020)
Published in Bone (New York, N.Y.) (01.07.2020)
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Journal Article
Co-targeting the MAPK and PI3K/AKT/mTOR pathways in two genetically engineered mouse models of schwann cell tumors reduces tumor grade and multiplicity
Watson, Adrienne L, Anderson, Leah K, Greeley, Andrew D, Keng, Vincent W, Rahrmann, Eric P, Halfond, Amanda L, Powell, Natasha M, Collins, Margaret H, Rizvi, Tilat, Moertel, Christopher L, Ratner, Nancy, Largaespada, David A
Published in Oncotarget (30.03.2014)
Published in Oncotarget (30.03.2014)
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Journal Article
Identification of PDE4D as a Proliferation Promoting Factor in Prostate Cancer Using a Sleeping Beauty Transposon-Based Somatic Mutagenesis Screen
RAHRMANN, Eric P, COLLIER, Lara S, WEI HUANG, LARGAESPADA, David A, MARKER, Paul C, KNUTSON, Todd P, DOYAL, Meghan E, KUSLAK, Sheri L, GREEN, Laura E, MALINOWSKI, Rita L, ROETHE, Laura, AKAGI, Keiko, WAKNITZ, Michelle
Published in Cancer research (Chicago, Ill.) (15.05.2009)
Published in Cancer research (Chicago, Ill.) (15.05.2009)
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Journal Article
Using RNA-seq and targeted nucleases to identify mechanisms of drug resistance in acute myeloid leukemia
Rathe, Susan K, Moriarity, Branden S, Stoltenberg, Christopher B, Kurata, Morito, Aumann, Natalie K, Rahrmann, Eric P, Bailey, Natashay J, Melrose, Ellen G, Beckmann, Dominic A, Liska, Chase R, Largaespada, David A
Published in Scientific reports (13.08.2014)
Published in Scientific reports (13.08.2014)
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Journal Article
Cancers make their own luck: theories of cancer origins
Jassim, Amir, Rahrmann, Eric P, Simons, Ben D, Gilbertson, Richard J
Published in Nature reviews. Cancer (01.10.2023)
Published in Nature reviews. Cancer (01.10.2023)
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Journal Article
Simple and efficient methods for enrichment and isolation of endonuclease modified cells
Moriarity, Branden S, Rahrmann, Eric P, Beckmann, Dominic A, Conboy, Caitlin B, Watson, Adrienne L, Carlson, Daniel F, Olson, Erik R, Hyland, Kendra A, Fahrenkrug, Scott C, McIvor, R Scott, Largaespada, David A
Published in PloS one (05.05.2014)
Published in PloS one (05.05.2014)
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Journal Article
Modular assembly of transposon integratable multigene vectors using RecWay assembly
Moriarity, Branden S, Rahrmann, Eric P, Keng, Vincent W, Manlove, Luke S, Beckmann, Dominic A, Wolf, Natalie K, Khurshid, Touba, Bell, Jason B, Largaespada, David A
Published in Nucleic acids research (01.04.2013)
Published in Nucleic acids research (01.04.2013)
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Journal Article
The NALCN channel regulates metastasis and nonmalignant cell dissemination
Rahrmann, Eric P, Shorthouse, David, Jassim, Amir, Hu, Linda P, Ortiz, Mariaestela, Mahler-Araujo, Betania, Vogel, Peter, Paez-Ribes, Marta, Fatemi, Atefeh, Hannon, Gregory J, Iyer, Radhika, Blundon, Jay A, Lourenço, Filipe C, Kay, Jonathan, Nazarian, Rosalynn M, Hall, Benjamin A, Zakharenko, Stanislav S, Winton, Douglas J, Zhu, Liqin, Gilbertson, Richard J
Published in Nature genetics (01.12.2022)
Published in Nature genetics (01.12.2022)
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Journal Article
A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis
Moriarity, Branden S, Otto, George M, Rahrmann, Eric P, Rathe, Susan K, Wolf, Natalie K, Weg, Madison T, Manlove, Luke A, LaRue, Rebecca S, Temiz, Nuri A, Molyneux, Sam D, Choi, Kwangmin, Holly, Kevin J, Sarver, Aaron L, Scott, Milcah C, Forster, Colleen L, Modiano, Jaime F, Khanna, Chand, Hewitt, Stephen M, Khokha, Rama, Yang, Yi, Gorlick, Richard, Dyer, Michael A, Largaespada, David A
Published in Nature genetics (01.06.2015)
Published in Nature genetics (01.06.2015)
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Journal Article
Conditional Inactivation of Pten with EGFR Overexpression in Schwann Cells Models Sporadic MPNST
Wallace, Margaret R., Ratner, Nancy, Largaespada, David A., Rizvi, Tilat A., Choi, Kwangmin, Moriarity, Branden S., Tschida, Barbara R., Li, Hua, Rahrmann, Eric P., Watson, Adrienne L., Keng, Vincent W., Collins, Margaret H.
Published in Complexity (New York, N.Y.) (2012)
Published in Complexity (New York, N.Y.) (2012)
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Journal Article
Implication of ZNF217 in Accelerating Tumor Development and Therapeutically Targeting ZNF217-Induced PI3K-AKT Signaling for the Treatment of Metastatic Osteosarcoma
Smeester, Branden A, Draper, Garrett M, Slipek, Nicholas J, Larsson, Alex T, Stratton, Natalie, Pomeroy, Emily J, Becklin, Kelsie L, Yamamoto, Kenta, Williams, Kyle B, Laoharawee, Kanut, Peterson, Joseph J, Abrahante, Juan E, Rathe, Susan K, Mills, Lauren J, Crosby, Margaret R, Hudson, Wendy A, Rahrmann, Eric P, Largaespada, David A, Moriarity, Branden S
Published in Molecular cancer therapeutics (01.12.2020)
Published in Molecular cancer therapeutics (01.12.2020)
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Journal Article
PTEN and NF1 Inactivation in Schwann Cells Produces a Severe Phenotype in the Peripheral Nervous System That Promotes the Development and Malignant Progression of Peripheral Nerve Sheath Tumors
KENG, Vincent W, RAHRMANN, Eric P, WATSON, Adrienne L, TSCHIDA, Barbara R, MOERTEL, Christopher L, JESSEN, Walter J, RIZVI, Tilat A, COLLINS, Margaret H, RATNER, Nancy, LARGAESPADA, David A
Published in Cancer research (Chicago, Ill.) (01.07.2012)
Published in Cancer research (Chicago, Ill.) (01.07.2012)
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Journal Article
SEMA4C is a novel target to limit osteosarcoma growth, progression, and metastasis
Smeester, Branden A, Slipek, Nicholas J, Pomeroy, Emily J, Bomberger, Heather E, Shamsan, Ghaidan A, Peterson, Joseph J, Crosby, Margaret R, Draper, Garrett M, Becklin, Kelsie L, Rahrmann, Eric P, McCarthy, James B, Odde, David J, Wood, David K, Largaespada, David A, Moriarity, Branden S
Published in Oncogene (30.01.2020)
Published in Oncogene (30.01.2020)
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Journal Article
Sleeping Beauty Screen Identifies RREB1 and Other Genetic Drivers in Human B-cell Lymphoma
Rahrmann, Eric P, Wolf, Natalie K, Otto, George M, Heltemes-Harris, Lynn, Ramsey, Laura B, Shu, Jingmin, LaRue, Rebecca S, Linden, Michael A, Rathe, Susan K, Starr, Timothy K, Farrar, Michael A, Moriarity, Branden S, Largaespada, David A
Published in Molecular cancer research (01.02.2019)
Published in Molecular cancer research (01.02.2019)
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Journal Article
Sleeping Beauty Insertional Mutagenesis Reveals Important Genetic Drivers of Central Nervous System Embryonal Tumors
Beckmann, Pauline J, Larson, Jon D, Larsson, Alex T, Ostergaard, Jason P, Wagner, Sandra, Rahrmann, Eric P, Shamsan, Ghaidan A, Otto, George M, Williams, Rory L, Wang, Jun, Lee, Catherine, Tschida, Barbara R, Das, Paramita, Dubuc, Adrian M, Moriarity, Branden S, Picard, Daniel, Wu, Xiaochong, Rodriguez, Fausto J, Rosemarie, Quincy, Krebs, Ryan D, Molan, Amy M, Demer, Addison M, Frees, Michelle M, Rizzardi, Anthony E, Schmechel, Stephen C, Eberhart, Charles G, Jenkins, Robert B, Wechsler-Reya, Robert J, Odde, David J, Huang, Annie, Taylor, Michael D, Sarver, Aaron L, Largaespada, David A
Published in Cancer research (Chicago, Ill.) (01.03.2019)
Published in Cancer research (Chicago, Ill.) (01.03.2019)
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Journal Article
Canonical Wnt/β-catenin signaling drives human schwann cell transformation, progression, and tumor maintenance
Watson, Adrienne L, Rahrmann, Eric P, Moriarity, Branden S, Choi, Kwangmin, Conboy, Caitlin B, Greeley, Andrew D, Halfond, Amanda L, Anderson, Leah K, Wahl, Brian R, Keng, Vincent W, Rizzardi, Anthony E, Forster, Colleen L, Collins, Margaret H, Sarver, Aaron L, Wallace, Margaret R, Schmechel, Stephen C, Ratner, Nancy, Largaespada, David A
Published in Cancer discovery (01.06.2013)
Published in Cancer discovery (01.06.2013)
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Journal Article
KCNQ potassium channels modulate Wnt activity in gastro-oesophageal adenocarcinomas
Shorthouse, David, Zhuang, Lizhe, Rahrmann, Eric P, Kosmidou, Cassandra, Wickham Rahrmann, Katherine, Hall, Michael, Greenwood, Benedict, Devonshire, Ginny, Gilbertson, Richard J, Fitzgerald, Rebecca C, Hall, Benjamin A
Published in Life science alliance (01.12.2023)
Published in Life science alliance (01.12.2023)
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