Predicting Antibody Developability Profiles Through Early Stage Discovery Screening
Bailly, Marc, Mieczkowski, Carl, Juan, Veronica, Metwally, Essam, Tomazela, Daniela, Baker, Jeanne, Uchida, Makiko, Kofman, Ester, Raoufi, Fahimeh, Motlagh, Soha, Yu, Yao, Park, Jihea, Raghava, Smita, Welsh, John, Rauscher, Michael, Raghunathan, Gopalan, Hsieh, Mark, Chen, Yi-Ling, Nguyen, Hang Thu, Nguyen, Nhung, Cipriano, Dan, Fayadat-Dilman, Laurence
Published in mAbs (01.01.2020)
Published in mAbs (01.01.2020)
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Interleukin-10 contributes to reservoir establishment and persistence in SIV-infected macaques treated with antiretroviral therapy
Harper, Justin, Ribeiro, Susan P, Chan, Chi Ngai, Aid, Malika, Deleage, Claire, Micci, Luca, Pino, Maria, Cervasi, Barbara, Raghunathan, Gopalan, Rimmer, Eric, Ayanoglu, Gulesi, Wu, Guoxin, Shenvi, Neeta, Barnard, Richard Jo, Del Prete, Gregory Q, Busman-Sahay, Kathleen, Silvestri, Guido, Kulpa, Deanna A, Bosinger, Steven E, Easley, Kirk A, Howell, Bonnie J, Gorman, Dan, Hazuda, Daria J, Estes, Jacob D, Sekaly, Rafick-Pierre, Paiardini, Mirko
Published in The Journal of clinical investigation (15.04.2022)
Published in The Journal of clinical investigation (15.04.2022)
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Journal Article
Characterization and Modeling of Reversible Antibody Self-Association Provide Insights into Behavior, Prediction, and Correction
Mieczkowski, Carl, Cheng, Alan, Fischmann, Thierry, Hsieh, Mark, Baker, Jeanne, Uchida, Makiko, Raghunathan, Gopalan, Strickland, Corey, Fayadat-Dilman, Laurence
Published in Antibodies (Basel) (15.02.2021)
Published in Antibodies (Basel) (15.02.2021)
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Journal Article
Crystal Structure and Characterization of Human Heavy-Chain Only Antibodies Reveals a Novel, Stable Dimeric Structure Similar to Monoclonal Antibodies
Mieczkowski, Carl, Bahmanjah, Soheila, Yu, Yao, Baker, Jeanne, Raghunathan, Gopalan, Tomazela, Daniela, Hsieh, Mark, McCoy, Mark, Strickland, Corey, Fayadat-Dilman, Laurence
Published in Antibodies (Basel) (22.11.2020)
Published in Antibodies (Basel) (22.11.2020)
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Dual blockade of IL-10 and PD-1 leads to control of SIV viral rebound following analytical treatment interruption
Pereira Ribeiro, Susan, Strongin, Zachary, Soudeyns, Hugo, Ten-Caten, Felipe, Ghneim, Khader, Pacheco Sanchez, Gabriela, Xavier de Medeiros, Giuliana, Del Rio Estrada, Perla Mariana, Pelletier, Adam-Nicolas, Hoang, Timothy, Nguyen, Kevin, Harper, Justin, Jean, Sherrie, Wallace, Chelsea, Balderas, Robert, Lifson, Jeffrey D, Raghunathan, Gopalan, Rimmer, Eric, Pastuskova, Cinthia, Wu, Guoxin, Micci, Luca, Ribeiro, Ruy M, Chan, Chi Ngai, Estes, Jacob D, Silvestri, Guido, Gorman, Daniel M, Howell, Bonnie J, Hazuda, Daria J, Paiardini, Mirko, Sekaly, Rafick P
Published in Nature immunology (12.09.2024)
Published in Nature immunology (12.09.2024)
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Journal Article
Abstract 577: Antagonism of the co-inhibitory receptor BTLA enhances efficacy of anti-PD-1 treatment in murine syngeneic tumor models
Miselis, Nathan R., Linn, Douglas, Restaino, Clifford, Baral, Toya, Xia, Jane, Ueda, Roanna, Sawant, Anandi, Baker, Jeanne, Raghunathan, Gopalan, Wang1, Xinzhong, Bowman, Edward, Sukumar, Selvakumar
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Structural insights into humanization of anti-tissue factor antibody 10H10
Teplyakov, Alexey, Obmolova, Galina, Malia, Thomas J, Raghunathan, Gopalan, Martinez, Christian, Fransson, Johan, Edwards, Wilson, Connor, Judith, Husovsky, Matthew, Beck, Heena, Chi, Ellen, Fenton, Sandra, Zhou, Hong, Almagro, Juan Carlos, Gilliland, Gary L
Published in mAbs (17.02.2018)
Published in mAbs (17.02.2018)
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TIGIT ANTI-TIGIT ANTIBODIES
SEGHEZZI WOLFGANG, WILLIAMS SYBIL M. G, FAYADAT DILMAN LAURENCE, RAGHUNATHAN GOPALAN, LIANG LINDA, LAFACE DRAKE
Year of Publication 29.11.2019
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Year of Publication 29.11.2019
Patent
혈액 뇌 장벽 수송을 향상시키기 위한 인간화 및 안정화된 FC5 변이체
CAMERON THOMAS O, PEPINSKY R. BLAKE, RAGHUNATHAN GOPALAN, PEDERSON NELS E, SMITH BENJAMIN A, WEN DINGYI, FARRINGTON GRAHAM K, SULEA TRAIAN, HAQQANI ARSALAN S, LEHMANN ANDREAS, STANIMIROVIC DANICA
Year of Publication 10.09.2021
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Year of Publication 10.09.2021
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LAG3 - ANTI-LAG3 ANTIBODIES AND ANTIGEN-BINDING FRAGMENTS
MALEFYT RENE DE WAAL, FAYADAT DILMAN LAURENCE, RAGHUNATHAN GOPALAN, LIANG LINDA
Year of Publication 30.10.2019
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Year of Publication 30.10.2019
Patent
Characterization of a high-affinity human antibody with a disulfide bridge in the third complementarity-determining region of the heavy chain
Almagro, Juan Carlos, Raghunathan, Gopalan, Beil, Eric, Janecki, Dariusz J., Chen, Qiang, Dinh, Thai, LaCombe, Ann, Connor, Judy, Ware, Mark, Kim, Paul H., Swanson, Ronald V., Fransson, Johan
Published in Journal of molecular recognition (01.03.2012)
Published in Journal of molecular recognition (01.03.2012)
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Journal Article
Human Framework Adaptation of a Mouse Anti-Human IL-13 Antibody
Fransson, Johan, Teplyakov, Alexey, Raghunathan, Gopalan, Chi, Ellen, Cordier, Wendy, Dinh, Thai, Feng, Yiqing, Giles-Komar, Jill, Gilliland, Gary, Lollo, Bridget, Malia, Thomas J., Nishioka, Walter, Obmolova, Galina, Zhao, Shanrong, Zhao, Yonghong, Swanson, Ronald V., Almagro, Juan C.
Published in Journal of molecular biology (30.04.2010)
Published in Journal of molecular biology (30.04.2010)
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인지 장애를 치료 또는 예방하기 위한 인간화된 항체, 이것을 생산하는 공정, 및 이것을 사용하여 인지 장애를 치료 또는 예방하기 위한 제제
MALASHOCK DANIEL STEPHEN, JABLONSKI ANGELA MARIE, RAGHUNATHAN GOPALAN (RAGHU), EGUCHI HIROSHI, PARMENTIER BATTEUR SOPHIE, NAMIKI NAOKO, MURAKAMI TAKASHI, TANOKURA AKIRA, MIECZKOWSKI CARL, BAKER JEANNE E
Year of Publication 30.10.2019
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Year of Publication 30.10.2019
Patent
LAG3 - ANTI-LAG3 ANTIBODIES AND ANTIGEN-BINDING FRAGMENTS
MALEFYT RENE DE WAAL, FAYADAT DILMAN LAURENCE, RAGHUNATHAN GOPALAN, LIANG LINDA
Year of Publication 21.04.2017
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Year of Publication 21.04.2017
Patent
TIGIT ANTI-TIGIT ANTIBODIES
SEGHEZZI WOLFGANG, WILLIAMS SYBIL M. G, FAYADAT DILMAN LAURENCE, RAGHUNATHAN GOPALAN, LIANG LINDA, LAFACE DRAKE
Year of Publication 14.04.2017
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Year of Publication 14.04.2017
Patent
HUMAN TISSUE FACTOR ANTIBODY AND USES THEREOF
ALMAGRO JUAN CARLOS, TEPLYAKOV ALEXEY, WU SHENG JIUM, CHI ELLEN, RAGHUNATHAN GOPALAN, SWANSON RONALD, TSE KAM FAI, ZHOU HONG MIMI, MARTINEZ CHRISTIAN, ANDERSON GLENN MARK
Year of Publication 14.02.2014
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Year of Publication 14.02.2014
Patent