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Levels of the DNA repair enzyme human apurinic/apyrimidinic endonuclease (APE1, APEX, Ref-1) are associated with the intrinsic radiosensitivity of cervical cancers
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Depletion of O6-alkylguanine-DNA alkyltransferase correlates with potentiation of temozolomide and CCNU toxicity in human tumour cells
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Genotoxicity studies on the azo dye Direct Red 2 using the in vivo mouse bone marrow micronucleus test
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Assays to predict the genotoxicity of the chromosomal mutagen etoposide — focussing on the best assay
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Engineering drug resistance in human cells
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The effects of dose, route of administration, drug scheduling and MDR-1 gene transfer on the genotoxicity of etoposide in bone marrow
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Chemoprotection of normal tissues by transfer of drug resistance genes
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Published in Cancer and metastasis reviews (01.09.1996)
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Expression levels of the DNA repair enzyme HAP1 do not correlate with the radiosensitivities of human or HAP1-transfected rat cell lines
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Protection of committed murine haemopoietic progenitors against BCNU toxicity does not predict protection of primitive, multipotent spleen colony-forming cells : implications for chemoprotective gene therapy
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Chemoprotective gene transfer I : Transduction of human haemopoietic progenitors with O6-benzylguanine-resistant O6-alkylguanine-DNA alkyltransferase attenuates the toxic effects of O6-alkylating agents in vitro
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Gene transfer to augment the therapeutic index of anticancer chemotherapy
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Published in Gene therapy (01.01.1996)
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Published in Gene therapy (01.01.1996)
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Chemoprotective gene transfer II : Multilineage in vivo protection of haemopoiesis against the effects of an antitumour agent by expression of a mutant human O6-alkylguanine-DNA alkyltransferase
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Contribution of ogt-encoded alkyltransferase to resistance to chloroethylnitrosoureas in nucleotide excision repair-deficient Escherichia coli
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The expression of full length Gp91-phox protein is associated with reduced amphotropic retroviral production
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Published in Haematologica (Roma) (01.05.2000)
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Role of nucleotide excision repair in processing of O4-alkylthymines in human cells
Klein, J C, Bleeker, M J, Roelen, H C, Rafferty, J A, Margison, G P, Brugghe, H F, van den Elst, H, van der Marel, G A, van Boom, J H, Kriek, E
Published in The Journal of biological chemistry (14.10.1994)
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