An alignment-independent three-dimensional quantitative structure-activity relationship study on ron receptor tyrosine kinase inhibitors
Zarei, Omid, Raeppel, Stéphane L, Hamzeh-Mivehroud, Maryam
Published in Journal of bioinformatics and computational biology (01.06.2022)
Published in Journal of bioinformatics and computational biology (01.06.2022)
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When RON MET TAM in Mesothelioma: All Druggable for One, and One Drug for All?
Baird, Anne-Marie, Easty, David, Jarzabek, Monika, Shiels, Liam, Soltermann, Alex, Klebe, Sonja, Raeppel, Stéphane, MacDonagh, Lauren, Wu, Chengguang, Griggs, Kim, Kirschner, Michaela B, Stanfill, Bryan, Nonaka, Daisuke, Goparaju, Chandra M, Murer, Bruno, Fennell, Dean A, O'Donnell, Dearbhaile M, Barr, Martin P, Mutti, Luciano, Reid, Glen, Finn, Stephen, Cuffe, Sinead, Pass, Harvey I, Opitz, Isabelle, Byrne, Annette T, O'Byrne, Kenneth J, Gray, Steven G
Published in Frontiers in endocrinology (Lausanne) (26.02.2019)
Published in Frontiers in endocrinology (Lausanne) (26.02.2019)
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A potential signaling axis between RON kinase receptor and hypoxia‐inducible factor‐1 alpha in pancreatic cancer
Kato, Akihisa, Ng, Serina, Thangasamy, Amalraj, Han, Haiyong, Zhou, Wendi, Raeppel, Stephane, Fallon, Michael, Guha, Sushovan, Ammanamanchi, Sudhakar
Published in Molecular carcinogenesis (01.11.2021)
Published in Molecular carcinogenesis (01.11.2021)
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Journal Article
Cover Image, Volume 60, Issue 11
Kato, Akihisa, Ng, Serina, Thangasamy, Amalraj, Han, Haiyong, Zhou, Wendi, Raeppel, Stephane, Fallon, Michael, Guha, Sushovan, Ammanamanchi, Sudhakar
Published in Molecular carcinogenesis (01.11.2021)
Published in Molecular carcinogenesis (01.11.2021)
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N-(4-(6,7-Disubstituted-quinolin-4-yloxy)-3-fluorophenyl)-2-oxo-3-phenylimidazolidine-1-carboxamides: A novel series of dual c-Met/VEGFR2 receptor tyrosine kinase inhibitors
Mannion, Michael, Raeppel, Stéphane, Claridge, Stephen, Zhou, Nancy, Saavedra, Oscar, Isakovic, Ljubomir, Zhan, Lijie, Gaudette, Frédéric, Raeppel, Franck, Déziel, Robert, Beaulieu, Normand, Nguyen, Hannah, Chute, Ian, Beaulieu, Carole, Dupont, Isabelle, Robert, Marie-France, Lefebvre, Sylvain, Dubay, Marja, Rahil, Jubrail, Wang, James, Ste-Croix, Hélène, Robert Macleod, A., Besterman, Jeffrey M., Vaisburg, Arkadii
Published in Bioorganic & medicinal chemistry letters (01.12.2009)
Published in Bioorganic & medicinal chemistry letters (01.12.2009)
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N-(3-fluoro-4-(2-arylthieno[3,2- b]pyridin-7-yloxy)phenyl)-2-oxo-3-phenylimidazolidine-1-carboxamides: A novel series of dual c-Met/VEGFR2 receptor tyrosine kinase inhibitors
Raeppel, Stéphane, Claridge, Stephen, Saavedra, Oscar, Gaudette, Frédéric, Zhan, Lijie, Mannion, Michael, Zhou, Nancy, Raeppel, Franck, Granger, Marie-Claude, Isakovic, Ljubomir, Déziel, Robert, Nguyen, Hannah, Beaulieu, Normand, Beaulieu, Carole, Dupont, Isabelle, Robert, Marie-France, Lefebvre, Sylvain, Dubay, Marja, Rahil, Jubrail, Wang, James, Ste-Croix, Hélène, Robert Macleod, A., Besterman, Jeffrey, Vaisburg, Arkadii
Published in Bioorganic & medicinal chemistry letters (01.03.2009)
Published in Bioorganic & medicinal chemistry letters (01.03.2009)
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Identification of potent and selective VEGFR receptor tyrosine kinase inhibitors having new amide isostere headgroups
Gaudette, Frédéric, Raeppel, Stéphane, Nguyen, Hannah, Beaulieu, Normand, Beaulieu, Carole, Dupont, Isabelle, Macleod, A. Robert, Besterman, Jeffrey M., Vaisburg, Arkadii
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
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Journal Article
Identification of a novel series of potent RON receptor tyrosine kinase inhibitors
Raeppel, Stéphane, Gaudette, Frédéric, Mannion, Michael, Claridge, Stephen, Saavedra, Oscar, Isakovic, Ljubomir, Déziel, Robert, Beaulieu, Normand, Beaulieu, Carole, Dupont, Isabelle, Nguyen, Hannah, Wang, James, Macleod, A. Robert, Maroun, Christiane, Besterman, Jeffrey M., Vaisburg, Arkadii
Published in Bioorganic & medicinal chemistry letters (01.05.2010)
Published in Bioorganic & medicinal chemistry letters (01.05.2010)
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Journal Article
Design and synthesis of 4-[( s-triazin-2-ylamino)methyl]- N-(2-aminophenyl)-benzamides and their analogues as a novel class of histone deacetylase inhibitors
Paquin, Isabelle, Raeppel, Stéphane, Leit, Silvana, Gaudette, Frédéric, Zhou, Nancy, Moradei, Oscar, Saavedra, Oscar, Bernstein, Naomy, Raeppel, Franck, Bouchain, Giliane, Fréchette, Sylvie, Woo, Soon H., Vaisburg, Arkadii, Fournel, Marielle, Kalita, Ann, Robert, Marie-France, Lu, Aihua, Trachy-Bourget, Marie-Claude, Yan, Pu Theresa, Liu, Jianhong, Rahil, Jubrail, MacLeod, A. Robert, Besterman, Jeffrey M., Li, Zuomei, Delorme, Daniel
Published in Bioorganic & medicinal chemistry (01.02.2008)
Published in Bioorganic & medicinal chemistry (01.02.2008)
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Discovery of N-(2-Aminophenyl)-4-[(4-pyridin-3-ylpyrimidin-2-ylamino)methyl]benzamide (MGCD0103), an Orally Active Histone Deacetylase Inhibitor
Zhou, Nancy, Moradei, Oscar, Raeppel, Stephane, Leit, Silvana, Frechette, Sylvie, Gaudette, Frederic, Paquin, Isabelle, Bernstein, Naomy, Bouchain, Giliane, Vaisburg, Arkadii, Jin, Zhiyun, Gillespie, Jeff, Wang, James, Fournel, Marielle, Yan, Pu T, Trachy-Bourget, Marie-Claude, Kalita, Ann, Lu, Aihua, Rahil, Jubrail, MacLeod, A. Robert, Li, Zuomei, Besterman, Jeffrey M, Delorme, Daniel
Published in Journal of medicinal chemistry (24.07.2008)
Published in Journal of medicinal chemistry (24.07.2008)
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Identification of a Novel Series of Potent TrkA Receptor Tyrosine Kinase Inhibitors
Raeppel, Stéphane L., Gaudette, Frédéric, Nguyen, Hannah, Beaulieu, Normand, Wang, James, Maroun, Christiane, Besterman, Jeffrey M., Vaisburg, Arkadii
Published in International Journal of Medicinal Chemistry (Online) (01.01.2012)
Published in International Journal of Medicinal Chemistry (Online) (01.01.2012)
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SAR and biological evaluation of analogues of a small molecule histone deacetylase inhibitor N-(2-aminophenyl)-4-((4-(pyridin-3-yl)pyrimidin-2-ylamino)methyl)benzamide ( MGCD0103)
Raeppel, Stéphane, Zhou, Nancy, Gaudette, Frédéric, Leit, Silvana, Paquin, Isabelle, Larouche, Guillaume, Moradei, Oscar, Fréchette, Sylvie, Isakovic, Ljubomir, Delorme, Daniel, Fournel, Marielle, Kalita, Ann, Lu, Aihua, Trachy-Bourget, Marie-Claude, Yan, Pu Theresa, Liu, Jianhong, Rahil, Jubrail, Wang, James, Besterman, Jeffrey M., Murakami, Koji, Li, Zuomei, Vaisburg, Arkadii
Published in Bioorganic & medicinal chemistry letters (01.02.2009)
Published in Bioorganic & medicinal chemistry letters (01.02.2009)
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Substituted N-(2-aminophenyl)-benzamides, ( E)- N-(2-aminophenyl)-acrylamides and their analogues: Novel classes of histone deacetylase inhibitors
Moradei, Oscar, Leit, Silvana, Zhou, Nancy, Fréchette, Sylvie, Paquin, Isabelle, Raeppel, Stéphane, Gaudette, Frédéric, Bouchain, Giliane, Woo, Soon H., Vaisburg, Arkadii, Fournel, Marielle, Kalita, Ann, Lu, Aihua, Trachy-Bourget, Marie-Claude, Yan, Pu T., Liu, Jianhong, Li, Zuomei, Rahil, Jubrail, MacLeod, A. Robert, Besterman, Jeffrey M., Delorme, Daniel
Published in Bioorganic & medicinal chemistry letters (01.08.2006)
Published in Bioorganic & medicinal chemistry letters (01.08.2006)
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4-(Heteroarylaminomethyl)- N-(2-aminophenyl)-benzamides and their analogs as a novel class of histone deacetylase inhibitors
Fréchette, Sylvie, Leit, Silvana, Woo, Soon Hyung, Lapointe, Guillaume, Jeannotte, Guillaume, Moradei, Oscar, Paquin, Isabelle, Bouchain, Giliane, Raeppel, Stéphane, Gaudette, Frédéric, Zhou, Nancy, Vaisburg, Arkadii, Fournel, Marielle, Yan, Pu Theresa, Trachy-Bourget, Marie-Claude, Kalita, Ann, Robert, Marie-France, Lu, Aihua, Rahil, Jubrail, Robert MacLeod, A., Besterman, Jeffrey M., Li, Zuomei, Delorme, Daniel
Published in Bioorganic & medicinal chemistry (15.02.2008)
Published in Bioorganic & medicinal chemistry (15.02.2008)
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Abstract 930: Preclinical characterization of MG516, a novel inhibitor of receptor tyrosine kinases involved in resistance to targeted therapies
Beaulieu, Normand, Sainte-Croix, Helene, Bonfils, Claire, Mannion, Michael, Raeppel, Stephane, Isakovic, Lubo, Claridge, Stephen, Saavedra, Oscar, Raeppel, Franck, Vaisburg, Arkadii, Wang, James, Fournel, Marielle, Besterman, Jeffrey M., Maroun, Christiane R.
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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