Of ticks, mice and men: understanding the dual-host lifestyle of Lyme disease spirochaetes
Radolf, Justin D., Caimano, Melissa J., Stevenson, Brian, Hu, Linden T.
Published in Nature reviews. Microbiology (01.02.2012)
Published in Nature reviews. Microbiology (01.02.2012)
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Treponema pallidum, the syphilis spirochete: making a living as a stealth pathogen
Radolf, Justin D., Deka, Ranjit K., Anand, Arvind, Šmajs, David, Norgard, Michael V., Yang, X. Frank
Published in Nature reviews. Microbiology (01.12.2016)
Published in Nature reviews. Microbiology (01.12.2016)
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BosR and PlzA reciprocally regulate RpoS function to sustain Borrelia burgdorferi in ticks and mammals
Grassmann, André A, Tokarz, Rafal, Golino, Caroline, McLain, Melissa A, Groshong, Ashley M, Radolf, Justin D, Caimano, Melissa J
Published in The Journal of clinical investigation (01.03.2023)
Published in The Journal of clinical investigation (01.03.2023)
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A suite of PCR-LwCas13a assays for detection and genotyping of Treponema pallidum in clinical samples
Chen, Wentao, Luo, Hao, Zeng, Lihong, Pan, Yuying, Parr, Jonathan B., Jiang, Yinbo, Cunningham, Clark H., Hawley, Kelly L., Radolf, Justin D., Ke, Wujian, Ou, Jiangli, Yang, Jianjiang, Yang, Bin, Zheng, Heping
Published in Nature communications (09.08.2022)
Published in Nature communications (09.08.2022)
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Analysis of Treponema pallidum Strains From China Using Improved Methods for Whole-Genome Sequencing From Primary Syphilis Chancres
Chen, Wentao, Šmajs, David, Hu, Yongfei, Ke, Wujian, Pospíšilová, Petra, Hawley, Kelly L, Caimano, Melissa J, Radolf, Justin D, Sena, Arlene, Tucker, Joseph D, Yang, Bin, Juliano, Jonathan J, Zheng, Heping, Parr, Jonathan B
Published in The Journal of infectious diseases (03.03.2021)
Published in The Journal of infectious diseases (03.03.2021)
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A systematic review of syphilis serological treatment outcomes in HIV-infected and HIV-uninfected persons: rethinking the significance of serological non-responsiveness and the serofast state after therapy
Seña, Arlene C, Zhang, Xiao-Hui, Li, Trudy, Zheng, He-Ping, Yang, Bin, Yang, Li-Gang, Salazar, Juan C, Cohen, Myron S, Moody, M Anthony, Radolf, Justin D, Tucker, Joseph D
Published in BMC infectious diseases (28.10.2015)
Published in BMC infectious diseases (28.10.2015)
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Viscous Dynamics of Lyme Disease and Syphilis Spirochetes Reveal Flagellar Torque and Drag
Harman, Michael, Vig, Dhruv K., Radolf, Justin D., Wolgemuth, Charles W.
Published in Biophysical journal (19.11.2013)
Published in Biophysical journal (19.11.2013)
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The RpoS Gatekeeper in Borrelia burgdorferi : An Invariant Regulatory Scheme That Promotes Spirochete Persistence in Reservoir Hosts and Niche Diversity
Caimano, Melissa J, Groshong, Ashley M, Belperron, Alexia, Mao, Jialing, Hawley, Kelly L, Luthra, Amit, Graham, Danielle E, Earnhart, Christopher G, Marconi, Richard T, Bockenstedt, Linda K, Blevins, Jon S, Radolf, Justin D
Published in Frontiers in microbiology (21.08.2019)
Published in Frontiers in microbiology (21.08.2019)
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Evidence that immunization with TP0751, a bipartite Treponema pallidum lipoprotein with an intrinsically disordered region and lipocalin fold, fails to protect in the rabbit model of experimental syphilis
Luthra, Amit, Montezuma-Rusca, Jairo M, La Vake, Carson J, LeDoyt, Morgan, Delgado, Kristina N, Davenport, Timothy C, Fiel-Gan, Mary, Caimano, Melissa J, Radolf, Justin D, Hawley, Kelly L
Published in PLoS pathogens (16.09.2020)
Published in PLoS pathogens (16.09.2020)
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Phagosomal signaling by Borrelia burgdorferi in human monocytes involves Toll-like receptor (TLR) 2 and TLR8 cooperativity and TLR8-mediated induction of IFN-β
Cervantes, Jorge L, Dunham-Ems, Star M, La Vake, Carson J, Petzke, Mary M, Sahay, Bikash, Sellati, Timothy J, Radolf, Justin D, Salazar, Juan C
Published in Proceedings of the National Academy of Sciences - PNAS (01.03.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (01.03.2011)
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PlzA is a bifunctional c-di-GMP biosensor that promotes tick and mammalian host-adaptation of Borrelia burgdorferi
Groshong, Ashley M, Grassmann, André A, Luthra, Amit, McLain, Melissa A, Provatas, Anthony A, Radolf, Justin D, Caimano, Melissa J
Published in PLoS pathogens (15.07.2021)
Published in PLoS pathogens (15.07.2021)
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Outcomes From Re-Treatment and Cerebrospinal Fluid Analyses in Patients With Syphilis Who Had Serological Nonresponse or Lack of Seroreversion After Initial Therapy
Zhang, Xiaohui, Shahum, Andrea, Yang, Li-Gang, Xue, Yaohua, Wang, Liuyuan, Yang, Bin, Zheng, Heping, Chen, Jane S, Radolf, Justin D, Seña, Arlene C
Published in Sexually transmitted diseases (01.06.2021)
Published in Sexually transmitted diseases (01.06.2021)
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Bacterial Indole as a Multifunctional Regulator of Klebsiella oxytoca Complex Enterotoxicity
Ledala, Nagender, Malik, Mishika, Rezaul, Karim, Paveglio, Sara, Provatas, Anthony, Kiel, Aaron, Caimano, Melissa, Zhou, Yanjiao, Lindgren, Jonathan, Krasulova, Kristyna, Illes, Peter, Dvořák, Zdeněk, Kortagere, Sandhya, Kienesberger, Sabine, Cosic, Amar, Pöltl, Lisa, Zechner, Ellen L, Ghosh, Subho, Mani, Sridhar, Radolf, Justin D, Matson, Adam P
Published in mBio (22.02.2022)
Published in mBio (22.02.2022)
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heterogeneous motility of the Lyme disease spirochete in gelatin mimics dissemination through tissue
Harman, Michael W, Dunham-Ems, Star M, Caimano, Melissa J, Belperron, Alexia A, Bockenstedt, Linda K, Fu, Henry C, Radolf, Justin D, Wolgemuth, Charles W
Published in Proceedings of the National Academy of Sciences - PNAS (21.02.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (21.02.2012)
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Use of Epivolve phage display to generate a monoclonal antibody with opsonic activity directed against a subdominant epitope on extracellular loop 4 of Treponema pallidum BamA (TP0326)
Ferguson, Mary R, Delgado, Kristina N, McBride, Shannon, Orbe, Isabel C, La Vake, Carson J, Caimano, Melissa J, Mendez, Qiana, Moraes, Trevor F, Schryvers, Anthony B, Moody, M Anthony, Radolf, Justin D, Weiner, Michael P, Hawley, Kelly L
Published in Frontiers in immunology (22.08.2023)
Published in Frontiers in immunology (22.08.2023)
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The Hybrid Histidine Kinase Hk1 Is Part of a Two-Component System That Is Essential for Survival of Borrelia burgdorferi in Feeding Ixodes scapularis Ticks
CAIMANO, Melissa J, KENEDY, Melisha R, KAIRU, Toru, DESROSIERS, Daniel C, HARMAN, Michael, DUNHAM-EMS, Star, AKINS, Darrin R, PAL, Utpal, RADOLF, Justin D
Published in Infection and Immunity (01.08.2011)
Published in Infection and Immunity (01.08.2011)
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Surface Immunolabeling and Consensus Computational Framework To Identify Candidate Rare Outer Membrane Proteins of Treponema pallidum
COX, David L, LUTHRA, Amit, DUNHAM-EMS, Star, DESROSIERS, Daniel C, SALAZAR, Juan C, CAIMANO, Melissa J, RADOLF, Justin D
Published in Infection and Immunity (01.12.2010)
Published in Infection and Immunity (01.12.2010)
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