Harnessing the fcμ receptor for potent and selective cytotoxic therapy of chronic lymphocytic leukemia
Vire, Bérengère, Skarzynski, Martin, Thomas, Joshua D, Nelson, Christopher G, David, Alexandre, Aue, Georg, Burke, Jr, Terrence R, Rader, Christoph, Wiestner, Adrian
Published in Cancer research (Chicago, Ill.) (15.12.2014)
Published in Cancer research (Chicago, Ill.) (15.12.2014)
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Immunoliposomal Delivery of Mir-29b By Targeting Tumor Antigen ROR1 Induces Epigenetic Reprograming in Human-ROR1-Expressed Mouse Model of Chronic Lymphocytic Leukemia
Chiang, Chi-Ling, Frissora, Frank W, Xie, Zhiliang, Huang, Xiaomeng, Mani, Rajeswaran, Baskar, Sivasubramanian, Rader, Christoph, Chan, Kenneth K., Marcucci, Guido, Byrd, John C., Lee, L. James, Muthusamy, Natarajan
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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Abstract 4406: ROR1 targeted delivery of OSU-2S, a non-immunosuppressive FTY720 derivative, exerts potent cytotoxicity in mantle cell lymphoma in-vitro and in-vivo
Mani, Rajeswaran, Chiang, Chi-Ling, Frissora, Frank W., Yan, Ribai, Mo, Xiaokui, Baskar, Sivasubramanian, Rader, Christoph, Phelps, Mitch, Chen, Ching-Shih, Lee, Robert, Byrd, John, Baiocchi, Robert, Lee, L James, Muthusamy, Natarajan
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Mechanisms of CNS myelin inhibition: evidence for distinct and neuronal cell type specific receptor systems
Giger, Roman J, Venkatesh, Karthik, Chivatakarn, Onanong, Raiker, Stephen J, Robak, Laurie, Hofer, Thomas, Lee, Hakjoo, Rader, Christoph
Published in Restorative neurology and neuroscience (2008)
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Published in Restorative neurology and neuroscience (2008)
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Fcμ-Receptor (FcμR; TOSO/FAIM3) Mediated Internalization of Antibody-Drug Conjugates: A Novel Approach to Selectively Target Chronic Lymphocytic Leukemia Cells
Vire, Berengere, David, Alexandre, Thomas, Joshua D, Burke, Terrence R, Rader, Christoph, Wiestner, Adrian
Published in Blood (18.11.2011)
Published in Blood (18.11.2011)
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OSU-2S: a novel non-immunosuppressive FTY720 derivative mediates potent cytotoxic activity through PKC dependent phosphorylation of tumor suppressor SHP1 and down modulation of Tcl1 oncogene in chronic lymphocytic leukemia (P2120)
Mani, Rajeswaran, Frissora, Frank, Mao, Yicheng, Chiang, Chi-ling, Mo, Xiaokui, Jarjoura, David, Baskar, Sivasubramanian, Rader, Christoph, Lee, Robert, Lee, L.James, Chen, Ching-Shih, Byrd, John, Muthusamy, Natarajan
Published in The Journal of immunology (1950) (01.05.2013)
Published in The Journal of immunology (1950) (01.05.2013)
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ROR1 targeted delivery of OSU-2S, a non-immunosuppressive FTY720 derivative exerts potent cytotoxicity in mantle cell lymphoma in-vitro and in-vivo
Mani, Rajeswaran, Chiang, Chi-Ling, Frissora, Frank W., Yan, Ribai, Mo, Xiaokui, Baskar, Sivasubramanian, Rader, Christoph, Klisovic, Rebecca, Phelps, Mitch A, Chen, Ching-Shih, Lee, Robert J., Byrd, John C., Baiocchi, Robert, Lee, L. James, Muthusamy, Natarajan
Published in Experimental hematology (29.04.2015)
Published in Experimental hematology (29.04.2015)
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Generation of a Platform for Identification of CLL Specific Cell Surface Proteins Targeted by Anti-Tumor Antibodies in Patient Sera After Allogeneic Hematopoietic Cell Transplantion
Shaffer, Brian C, Leitner, Judith, Wiestner, Adrian, Bishop, Michael R., Pavletic, Steven Z., Gress, Ronald E., Steinberger, Peter, Baskar, Sivasubramanian, Rader, Christoph
Published in Blood (16.11.2012)
Published in Blood (16.11.2012)
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Novel Antigen-Specific Expansion of T Cells Transduced with a CD19 Chimeric Antigen Receptor
Lee, Daniel W., Kochenderfer, James N, Rader, Christoph, Orentas, Rimas J, Mackall, Crystal L
Published in Blood (19.11.2010)
Published in Blood (19.11.2010)
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Generation, Affinity Maturation, and Characterization of a Human Anti-Human NKG2D Monoclonal Antibody with Dual Antagonistic and Agonistic Activity
Kwong, Ka Yin, Baskar, Sivasubramanian, Zhang, Hua, Mackall, Crystal L., Rader, Christoph
Published in Journal of molecular biology (31.12.2008)
Published in Journal of molecular biology (31.12.2008)
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ROR1 directed delivery of FTY720 derivative OSU-2S mediates potent cytotoxic activity against chronic lymphocytic leukemia but not normal B cells in-vitro and in ROR1 expressing transgenic CLL mouse model in-vivo (P3275)
Muthusamy, Natarajan, Mao, Yicheng, Frissora, Frank, Mani, Rajeswaran, Wang, Jiang, Wu, Yun, Yu, Bo, Baskar, Sivasubramanian, Rader, Christoph, Phelphs, Mitch, Chen, Ching-Shih, Lee, Robert, Lee, L., Byrd, John
Published in The Journal of immunology (1950) (01.05.2013)
Published in The Journal of immunology (1950) (01.05.2013)
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A human monoclonal antibody drug and target discovery platform for B-cell chronic lymphocytic leukemia based on allogeneic hematopoietic stem cell transplantation and phage display
Baskar, Sivasubramanian, Suschak, Jessica M., Samija, Ivan, Srinivasan, Ramaprasad, Childs, Richard W., Pavletic, Steven Z., Bishop, Michael R., Rader, Christoph
Published in Blood (12.11.2009)
Published in Blood (12.11.2009)
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