To Catch a Killer: Delineating the Mechanistic Role of Siglec-6, a Novel Glycoprotein Target, for the Treatment of Chronic Lymphocytic Leukemia
Nunes, Jessica, Ventura, Ann, Zapolnik, Kevan, Mo, Xiaokui, Zhang, Liwen, Byrd, John C., Rader, Christoph, Muthusamy, Natarajan
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Testing of skeletal implant surfaces with human fetal osteoblasts
Hendrich, Christian, Nöth, Ulrich, Stahl, Ulrich, Merklein, Frank, Rader, Christoph P, Schütze, Norbert, Thull, Roger, Tuan, Rocky S, Eulert, Jochen
Published in Clinical orthopaedics and related research (01.01.2002)
Published in Clinical orthopaedics and related research (01.01.2002)
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Journal Article
Sculpting a Uniquely Reactive Cysteine Residue for Site-Specific Antibody Conjugation
Hwang, Dobeen, Nilchan, Napon, Park, HaJeung, Roy, Raktim N., Roush, William R., Rader, Christoph
Published in Bioconjugate chemistry (15.06.2022)
Published in Bioconjugate chemistry (15.06.2022)
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Journal Article
A 177Lu-labeled anti-HER2 dual variable domain antibody
MacPherson, Douglas, Hwang, Dobeen, Sarrett, Samantha, Rodriguez, Cindy, Keinaenen, Outi, Rader, Christoph, Zeglis, Brian
Published in Nuclear medicine and biology (01.11.2022)
Published in Nuclear medicine and biology (01.11.2022)
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Journal Article
O-12 - A 177Lu-labeled anti-HER2 dual variable domain antibody
MacPherson, Douglas, Hwang, Dobeen, Sarrett, Samantha, Rodriguez, Cindy, Keinaenen, Outi, Rader, Christoph, Zeglis, Brian
Published in Nuclear medicine and biology (01.11.2022)
Published in Nuclear medicine and biology (01.11.2022)
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Journal Article
Using Antibody Catalysis to Study the Outcome of Multiple Evolutionary Trials of a Chemical Task
Karlstrom, Amelie, Zhong, Guofu, Rader, Christoph, Larsen, Nicholas A., Heine, Andreas, Fuller, Roberta, List, Benjamin, Tanaka, Fujie, Wilson, Ian A., Barbas, Carlos F., Lerner, Richard A.
Published in Proceedings of the National Academy of Sciences - PNAS (11.04.2000)
Published in Proceedings of the National Academy of Sciences - PNAS (11.04.2000)
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Journal Article
Affinity maturation, humanization, and co-crystallization of a rabbit anti-human ROR2 monoclonal antibody for therapeutic applications
Goydel, Rebecca S., Weber, Justus, Peng, Haiyong, Qi, Junpeng, Soden, Jo, Freeth, Jim, Park, HaJeung, Rader, Christoph
Published in The Journal of biological chemistry (01.05.2020)
Published in The Journal of biological chemistry (01.05.2020)
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Journal Article
Delineating the mechanistic pathway and therapeutic potential of Siglec-6 in Chronic Lymphocytic Leukemia
Nunes, Jessica Judith, Ventura, Ann, Zapolnik, Kevan, Mo, Xiaokui, Zhang, Liwen, Chen, Min, Byrd, John, Rader, Christoph, Muthusamy, Natarajan
Published in The Journal of immunology (1950) (01.05.2022)
Published in The Journal of immunology (1950) (01.05.2022)
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Journal Article
Application of a Biocatalytic Strategy for the Preparation of Tiancimycin-Based Antibody–Drug Conjugates Revealing Key Insights into Structure–Activity Relationships
Steele, Andrew D., Kiefer, Alexander F., Hwang, Dobeen, Yang, Dong, Teijaro, Christiana N., Adhikari, Ajeeth, Rader, Christoph, Shen, Ben
Published in Journal of medicinal chemistry (26.01.2023)
Published in Journal of medicinal chemistry (26.01.2023)
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Journal Article
Defining the Biochemical Role of Sialic Acid-Binding Immunoglobulin-like Lectin-6 in Adhesion and Migration in Chronic Lymphocytic Leukemia
Nunes, Jessica, Ventura, Ann, Zapolnik, Kevan, Hu, Eileen, Zhang, Liwen, Mo, Xiaokui, Byrd, John C., Rader, Christoph, Muthusamy, Raj
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
BTK inhibitors, irrespective of ITK inhibition, increase efficacy of a CD19/CD3-bispecific antibody in CLL
Mhibik, Maissa, Gaglione, Erika M., Eik, David, Kendall, Ellen K., Blackburn, Amy, Keyvanfar, Keyvan, Baptista, Maria Joao, Ahn, Inhye E., Sun, Clare, Qi, Junpeng, Rader, Christoph, Wiestner, Adrian
Published in Blood (11.11.2021)
Published in Blood (11.11.2021)
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Journal Article
Concerted Antibody and Antigen Discovery by Differential Whole-cell Phage Display Selections and Multi-omic Target Deconvolution
Cyr, Matthew G., Wilson, Henry D., Spierling, Anna-Lena, Chang, Jing, Peng, Haiyong, Steinberger, Peter, Rader, Christoph
Published in Journal of molecular biology (15.05.2023)
Published in Journal of molecular biology (15.05.2023)
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Journal Article
An IgG1-like bispecific antibody targeting CD52 and CD20 for the treatment of B-cell malignancies
Qi, Junpeng, Chen, Shih-Shih, Chiorazzi, Nicholas, Rader, Christoph
Published in Methods (San Diego, Calif.) (01.02.2019)
Published in Methods (San Diego, Calif.) (01.02.2019)
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Journal Article
Functional Characterization of Cytochrome P450 Hydroxylase YpmL in Yangpumicin A Biosynthesis and Its Application for Anthraquinone-Fused Enediyne Structural Diversification
Yang, Dong, Ye, Fei, Teijaro, Christiana N, Hwang, Dobeen, Annaval, Thibault, Adhikari, Ajeeth, Li, Gengnan, Yan, Xiaohui, Gui, Chun, Rader, Christoph, Shen, Ben
Published in Organic letters (11.02.2022)
Published in Organic letters (11.02.2022)
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Journal Article
Improving the Serum Stability of Site-Specific Antibody Conjugates with Sulfone Linkers
Patterson, James T, Asano, Shigehiro, Li, Xiuling, Rader, Christoph, Barbas, Carlos F
Published in Bioconjugate chemistry (20.08.2014)
Published in Bioconjugate chemistry (20.08.2014)
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Journal Article
Defining the role of Siglec-6-DOCK8 axis in cell adhesion and migration in Chronic Lymphocytic Leukemia
Nunes, Jessica Judith, Ventura, Ann, Hu, Eileen, Zapolnik, Kevan, Mo, Xiaokui, Byrd, John, Rader, Christoph, Muthusamy, Natarajan
Published in The Journal of immunology (1950) (01.05.2021)
Published in The Journal of immunology (1950) (01.05.2021)
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Journal Article
A Sortase A Programmable Phage Display Format for Improved Panning of Fab Antibody Libraries
Wilson, Henry D., Li, Xiuling, Peng, Haiyong, Rader, Christoph
Published in Journal of molecular biology (19.10.2018)
Published in Journal of molecular biology (19.10.2018)
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Journal Article
Comparative Studies of the Biosynthetic Gene Clusters for Anthraquinone-Fused Enediynes Shedding Light into the Tailoring Steps of Tiancimycin Biosynthesis
Yan, Xiaohui, Chen, Jian-Jun, Adhikari, Ajeeth, Teijaro, Christiana N, Ge, Huiming, Crnovcic, Ivana, Chang, Chin-Yuan, Annaval, Thibault, Yang, Dong, Rader, Christoph, Shen, Ben
Published in Organic letters (21.09.2018)
Published in Organic letters (21.09.2018)
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Journal Article
Molecularly Defined Antibody Conjugation through a Selenocysteine Interface
Hofer, Thomas, Skeffington, Lauren R, Chapman, Colby M, Rader, Christoph
Published in Biochemistry (Easton) (22.12.2009)
Published in Biochemistry (Easton) (22.12.2009)
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Journal Article