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Published in PloS one (11.12.2020)
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Published in Nature communications (01.08.2017)
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In Vitro Activity and Preclinical Profile of TMC435350, a Potent Hepatitis C Virus Protease Inhibitor
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Cummings, Maxwell D, Lindberg, Jimmy, Lin, Tse -I, de Kock, Herman, Lenz, Oliver, Lilja, Elisabet, Felländer, Sara, Baraznenok, Vera, Nyström, Susanne, Nilsson, Magnus, Vrang, Lotta, Edlund, Michael, Rosenquist, Åsa, Samuelsson, Bertil, Raboisson, Pierre, Simmen, Kenneth
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Published in Journal of medicinal chemistry (27.07.2017)
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Structure–activity relationship study on a novel series of cyclopentane-containing macrocyclic inhibitors of the hepatitis C virus NS3/4A protease leading to the discovery of TMC435350
Raboisson, Pierre, de Kock, Herman, Rosenquist, Åsa, Nilsson, Magnus, Salvador-Oden, Lourdes, Lin, Tse-I, Roue, Natalie, Ivanov, Vladimir, Wähling, Horst, Wickström, Kristina, Hamelink, Elizabeth, Edlund, Michael, Vrang, Lotta, Vendeville, Sandrine, Van de Vreken, Wim, McGowan, David, Tahri, Abdellah, Hu, Lili, Boutton, Carlo, Lenz, Oliver, Delouvroy, Frederic, Pille, Geert, Surleraux, Dominique, Wigerinck, Piet, Samuelsson, Bertil, Simmen, Kenneth
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TMC647055, a Potent Nonnucleoside Hepatitis C Virus NS5B Polymerase Inhibitor with Cross-Genotypic Coverage
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Structure-Based Design of a Benzodiazepine Scaffold Yields a Potent Allosteric Inhibitor of Hepatitis C NS5B RNA Polymerase
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Published in Journal of Virology (01.07.2007)
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1a/1b Subtype Profiling of Nonnucleoside Polymerase Inhibitors of Hepatitis C Virus
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Inhibition of platelet function by administration of MRS2179, a P2Y1 receptor antagonist
BAURAND, Anthony, RABOISSON, Pierre, FREUND, Monique, LEON, Catherine, CAZENAVE, Jean-Pierre, BOURGUIGNON, Jean-Jacques, GACHET, Christian
Published in European journal of pharmacology (02.02.2001)
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Antiviral Activity and Mode of Action of TMC647078, a Novel Nucleoside Inhibitor of the Hepatitis C Virus NS5B Polymerase
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