Monoclonal antibody targeting BDCA2 ameliorates skin lesions in systemic lupus erythematosus
Furie, Richard, Werth, Victoria P, Merola, Joseph F, Stevenson, Lauren, Reynolds, Taylor L, Naik, Himanshu, Wang, Wenting, Christmann, Romy, Gardet, Agnes, Pellerin, Alex, Hamann, Stefan, Auluck, Pavan, Barbey, Catherine, Gulati, Parul, Rabah, Dania, Franchimont, Nathalie
Published in The Journal of clinical investigation (01.03.2019)
Published in The Journal of clinical investigation (01.03.2019)
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Acute inhibition of the CNS-specific kinase TTBK1 significantly lowers tau phosphorylation at several disease relevant sites
Dillon, Gregory M, Henderson, Jaclyn L, Bao, Channa, Joyce, John A, Calhoun, Michael, Amaral, Brenda, King, Kristopher W, Bajrami, Bekim, Rabah, Dania
Published in PloS one (07.04.2020)
Published in PloS one (07.04.2020)
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Pharmacological Inhibition of MALT1 Ameliorates Autoimmune Pathogenesis and Can Be Uncoupled From Effects on Regulatory T-Cells
Biswas, Subhabrata, Chalishazar, Aditi, Helou, Ynes, DiSpirito, Joanna, DeChristopher, Brian, Chatterjee, Devin, Merselis, Leidy, Vincent, Benjamin, Monroe, John G, Rabah, Dania, Long, Andrew J
Published in Frontiers in immunology (09.05.2022)
Published in Frontiers in immunology (09.05.2022)
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Effect of in vivo Hydroxychloroquine and ex vivo Anti-BDCA2 mAb Treatment on pDC IFNα Production From Patients Affected With Cutaneous Lupus Erythematosus
Gardet, Agnes, Pellerin, Alex, McCarl, Christie-Ann, Diwanji, Rohan, Wang, Wenting, Donaldson, Douglas, Franchimont, Nathalie, Werth, Victoria P, Rabah, Dania
Published in Frontiers in immunology (21.02.2019)
Published in Frontiers in immunology (21.02.2019)
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Anti‐BDCA2 monoclonal antibody inhibits plasmacytoid dendritic cell activation through Fc‐dependent and Fc‐independent mechanisms
Pellerin, Alex, Otero, Karel, Czerkowicz, Julie M, Kerns, Hannah M, Shapiro, Renée I, Ranger, Ann M, Otipoby, Kevin L, Taylor, Frederick R, Cameron, Thomas O, Viney, Joanne L, Rabah, Dania
Published in EMBO molecular medicine (01.04.2015)
Published in EMBO molecular medicine (01.04.2015)
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A clinical population pharmacokinetic/pharmacodynamic model for BIIB059, a monoclonal antibody for the treatment of systemic and cutaneous lupus erythematosus
Hartmann, Sonja, Biliouris, Konstantinos, Naik, Himanshu, Rabah, Dania, Stevenson, Lauren, Shen, Chase, Nestorov, Ivan A., Lesko, Lawrence J., Trame, Mirjam N.
Published in Journal of pharmacokinetics and pharmacodynamics (01.06.2020)
Published in Journal of pharmacokinetics and pharmacodynamics (01.06.2020)
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A promoter in the coding region of the calcium channel gene CACNA1C generates the transcription factor CCAT
Gomez-Ospina, Natalia, Panagiotakos, Georgia, Portmann, Thomas, Pasca, Sergiu P, Rabah, Dania, Budzillo, Agata, Kinet, Jean Pierre, Dolmetsch, Ricardo E
Published in PloS one (16.04.2013)
Published in PloS one (16.04.2013)
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Pristane-Accelerated Autoimmune Disease in (SWR X NZB) F1 Mice Leads to Prominent Tubulointerstitial Inflammation and Human Lupus Nephritis-Like Fibrosis
Gardet, Agnes, Chou, Wei C, Reynolds, Taylor L, Velez, Diana B, Fu, Kai, Czerkowicz, Julia M, Bajko, Jeffrey, Ranger, Ann M, Allaire, Normand, Kerns, Hannah M, Ryan, Sarah, Legault, Holly M, Dunstan, Robert W, Lafyatis, Robert, Lukashev, Matvey, Viney, Joanne L, Browning, Jeffrey L, Rabah, Dania
Published in PloS one (19.10.2016)
Published in PloS one (19.10.2016)
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RNA tape sampling in cutaneous lupus erythematosus discriminates affected from unaffected and healthy volunteer skin
Merola, Joseph F, Wang, Wenting, Wager, Carrie G, Hamann, Stefan, Zhang, Xueli, Thai, Alice, Roberts, Christopher, Lam, Christina, Musselli, Cristina, Marsh, Galina, Rabah, Dania, Barbey, Catherine, Franchimont, Nathalie, Reynolds, Taylor L
Published in Lupus science & medicine (03.03.2021)
Published in Lupus science & medicine (03.03.2021)
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Observational fear learning involves affective pain system and Cav1.2 Ca2+ channels in ACC
Jeon, Daejong, Kim, Sangwoo, Chetana, Mattu, Jo, Daewoong, Ruley, H Earl, Lin, Shih-Yao, Rabah, Dania, Kinet, Jean-Pierre, Shin, Hee-Sup
Published in Nature neuroscience (01.04.2010)
Published in Nature neuroscience (01.04.2010)
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Observational fear learning involves affective pain system and Ca v 1.2 Ca 2+ channels in ACC
Shin, Hee-Sup, Jeon, Daejong, Kim, Sangwoo, Chetana, Mattu, Jo, Daewoong, Ruley, H Earl, Lin, Shih-Yao, Rabah, Dania, Kinet, Jean-Pierre
Published in Nature neuroscience (01.04.2010)
Published in Nature neuroscience (01.04.2010)
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A pre-clinical quantitative model predicts the pharmacokinetics/pharmacodynamics of an anti-BDCA2 monoclonal antibody in humans
Biliouris, Konstantinos, Nestorov, Ivan, Naik, Himanshu, Dai, David, Xiao, Guangqing, Wang, Qin, Pellerin, Alex, Rabah, Dania, Lesko, Lawrence J., Trame, Mirjam N.
Published in Journal of pharmacokinetics and pharmacodynamics (01.12.2018)
Published in Journal of pharmacokinetics and pharmacodynamics (01.12.2018)
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EC144, a synthetic inhibitor of heat shock protein 90, blocks innate and adaptive immune responses in models of inflammation and autoimmunity
Yun, Theodore J, Harning, Erin K, Giza, Keith, Rabah, Dania, Li, Ping, Arndt, Joseph W, Luchetti, David, Biamonte, Marco A, Shi, Jiandong, Lundgren, Karen, Manning, Anthony, Kehry, Marilyn R
Published in The Journal of immunology (1950) (01.01.2011)
Published in The Journal of immunology (1950) (01.01.2011)
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The lymphotoxin β receptor is a potential therapeutic target in renal inflammation
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Published in Kidney international (01.01.2016)
Published in Kidney international (01.01.2016)
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2 ANTI-BLOOD DENDRITIC CELL ANTIGEN 2 ANTIBODIES AND USES THEREOF
RABAH DANIA MOUNIR, TAYLOR FREDERICK R, GARBER ELLEN A, CARAVELLA JUSTIN A
Year of Publication 18.11.2020
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Year of Publication 18.11.2020
Patent
Pristane-Accelerated Autoimmune Disease in
Gardet, Agnes, Chou, Wei C, Reynolds, Taylor L, Velez, Diana B, Fu, Kai, Czerkowicz, Julia M, Bajko, Jeffrey, Ranger, Ann M, Allaire, Normand, Kerns, Hannah M, Ryan, Sarah, Legault, Holly M, Dunstan, Robert W, Lafyatis, Robert, Lukashev, Matvey, Viney, Joanne L, Browning, Jeffrey L, Rabah, Dania
Published in PloS one (19.10.2016)
Published in PloS one (19.10.2016)
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Journal Article
Anti‐ BDCA 2 monoclonal antibody inhibits plasmacytoid dendritic cell activation through Fc‐dependent and Fc‐independent mechanisms
Pellerin, Alex, Otero, Karel, Czerkowicz, Julie M, Kerns, Hannah M, Shapiro, Renée I, Ranger, Ann M, Otipoby, Kevin L, Taylor, Frederick R, Cameron, Thomas O, Viney, Joanne L, Rabah, Dania
Published in EMBO molecular medicine (01.04.2015)
Published in EMBO molecular medicine (01.04.2015)
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Journal Article