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Published in Bioorganic & medicinal chemistry letters (01.10.2009)
Published in Bioorganic & medicinal chemistry letters (01.10.2009)
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Azaindole Hydroxamic Acids are Potent HIV-1 Integrase Inhibitors
Plewe, Michael B, Butler, Scott L, R. Dress, Klaus, Hu, Qiyue, Johnson, Ted W, Kuehler, Jon E, Kuki, Atsuo, Lam, Hieu, Liu, Wen, Nowlin, Dawn, Peng, Qinghai, Rahavendran, Sadayappan V, Tanis, Steven P, Tran, Khanh T, Wang, Hai, Yang, Anle, Zhang, Junhu
Published in Journal of medicinal chemistry (26.11.2009)
Published in Journal of medicinal chemistry (26.11.2009)
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Journal Article
Design and Synthesis of Novel N-Hydroxy-Dihydronaphthyridinones as Potent and Orally Bioavailable HIV-1 Integrase Inhibitors
Johnson, Ted W, Tanis, Steven P, Butler, Scott L, Dalvie, Deepak, DeLisle, Dorothy M, Dress, Klaus R, Flahive, Erik J, Hu, Qiyue, Kuehler, Jon E, Kuki, Atsuo, Liu, Wen, McClellan, Guy A, Peng, Qinghai, Plewe, Michael B, Richardson, Paul F, Smith, Graham L, Solowiej, Jim, Tran, Khanh T, Wang, Hai, Yu, Xiaoming, Zhang, Junhu, Zhu, Huichun
Published in Journal of medicinal chemistry (12.05.2011)
Published in Journal of medicinal chemistry (12.05.2011)
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N-(Pyridin-2-yl) arylsulfonamide inhibitors of 11β-hydroxysteroid dehydrogenase type 1: Strategies to eliminate reactive metabolites
Nair, Sajiv K., Matthews, Jean J., Cripps, Stephan J., Cheng, Hengmiao, Hoffman, Jacqui E., Smith, Christopher, Kupchinsky, Stanley, Siu, Michael, Taylor, Wendy D., Wang, Yong, Johnson, Theodore O., Dress, Klaus R., Edwards, Martin P., Zhou, Sue, Hosea, Natilie A., LaPaglia, Amy, Kang, Ping, Castro, Arturo, Ermolieff, Jacques, Fanjul, Andrea, Vogel, Jennifer E., Rejto, Paul, Dalvie, Deepak
Published in Bioorganic & medicinal chemistry letters (15.04.2013)
Published in Bioorganic & medicinal chemistry letters (15.04.2013)
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Journal Article
Azaindole N-methyl hydroxamic acids as HIV-1 integrase inhibitors-II. The impact of physicochemical properties on ADME and PK
Tanis, Steven P., Plewe, Michael B., Johnson, Ted W., Butler, Scott L., Dalvie, Deepak, DeLisle, Dorothy, Dress, Klaus R., Hu, Qiyue, Huang, Buwen, Kuehler, Jon E., Kuki, Atsuo, Liu, Wen, Peng, Qinghai, Smith, Graham L., Solowiej, Jim, Tran, Khanh T., Wang, Hai, Yang, Anle, Yin, Chunfeng, Yu, Xiaoming, Zhang, Junhu, Zhu, Huichun
Published in Bioorganic & medicinal chemistry letters (15.12.2010)
Published in Bioorganic & medicinal chemistry letters (15.12.2010)
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Journal Article
N-(Pyridin-2-yl) arylsulfonamide inhibitors of 11[beta]-hydroxysteroid dehydrogenase type 1: Strategies to eliminate reactive metabolites
Nair, Sajiv K, Matthews, Jean J, Cripps, Stephan J, Cheng, Hengmiao, Hoffman, Jacqui E, Smith, Christopher, Kupchinsky, Stanley, Siu, Michael, Taylor, Wendy D, Wang, Yong, Johnson, Theodore O, Dress, Klaus R, Edwards, Martin P, Zhou, Sue, Hosea, Natilie A, LaPaglia, Amy, Kang, Ping, Castro, Arturo, Ermolieff, Jacques, Fanjul, Andrea, Vogel, Jennifer E, Rejto, Paul, Dalvie, Deepak
Published in Bioorganic & medicinal chemistry letters (15.04.2013)
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Published in Bioorganic & medicinal chemistry letters (15.04.2013)
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Inhibitors of the Hiv Integrase Enzyme
KUEHLER JON E, ZHANG JUNHU, DRESS KLAUS R, YANG ANLE, PLEWE MICHAEL B
Year of Publication 04.10.2007
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Year of Publication 04.10.2007
Patent
INHIBITORS OF THE HIV INTEGRASE ENZYME
JOHNSON TED W, TANIS STEVEN P, ZHU HUICHUN, DRESS KLAUS R, PLEWE MICHAEL B
Year of Publication 03.05.2007
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Year of Publication 03.05.2007
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Novel compounds of amino sulfonyl derivatives
HUANG BUWEN, CRIPPS STEPHAN J, NAIR SAJIV K, DRESS KLAUS R, CHENG HENGMIAO, WANG YONG
Year of Publication 01.02.2007
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Year of Publication 01.02.2007
Patent
Inhibitors of the HIV integrase enzyme
HU QIYUE, JOHNSON TED W, TANIS STEVEN P, ZHU HUICHUN, ZHANG JUNHU, DRESS KLAUS R, PLEWE MICHAEL B
Year of Publication 15.12.2005
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Year of Publication 15.12.2005
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PYRROLOPYRIDINE DERIVATIVES AND THEIR USE AS HIV-INTEGRASE INHIBITORS
JOHNSON, TED W, ZHANG, JUNHU, PLEWE, MICHAEL B, WANG, HAI, YANG, ANLE, DRESS, KLAUS R, TANIS, STEVEN P, HU, QIYUE, YIN, CHUNFENG
Year of Publication 28.02.2007
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Year of Publication 28.02.2007
Patent
4-METHYLPYRIDOPYRIMIDINONE COMPOUNDS
BHUMRALKAR DILIP, KANIA ROBERT S, LE PHUONG T.Q, NAMBU MITCHELL D, HOFFMAN JACQUI E, DRESS KLAUS R, TRAN KHANH T, CHENG HENGMIAO, JOHNSON MARY C, PAIRISH MASON A, PLEWE MICHAEL B
Year of Publication 17.04.2008
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Year of Publication 17.04.2008
Patent
Inhibitors of the HIV integrase enzyme
HU QIYUE, YIN CHUNFENG, JOHNSON TED W, TANIS STEVEN P, ZHANG JUNHU, DRESS KLAUS R, YANG ANLE, WANG HAI, PLEWE MICHAEL B
Year of Publication 15.12.2005
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Year of Publication 15.12.2005
Patent
HIV protease inhibitors, compositions containing the same, their pharmaceutical uses and materials for their synthesis
HUANG BUWEN, LEWIS KATHLEEN K, DRESS KLAUS R, KUMPF ROBERT A, CANAN-KOCH STACIE S, MATTHEWS JEAN J, SAKATA SYLVIE K, ALEGRIA LARRY A, VIRGIL SCOTT C
Year of Publication 09.06.2005
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Year of Publication 09.06.2005
Patent
Novel compounds of proline and morpholine derivatives
SMITH CHRISTOPHER R, HUANG BUWEN, CRIPPS STEPHAN J, LE PHUONG T.Q, NAIR SAJIV K, HOFFMAN JACQUI E, DRESS KLAUS R, PARROTT TIMOTHY J, CHENG HENGMIAO, KUPCHINSKY STANLEY W, YANG YI, WANG YONG
Year of Publication 24.11.2005
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Year of Publication 24.11.2005
Patent