Search Results - "R. Bruce Rowley" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Discovery and SAR of Novel 2,3-Dihydroimidazo[1,2-c]quinazoline PI3K Inhibitors: Identification of Copanlisib (BAY 80-6946)

Discovery and SAR of Novel 2,3-Dihydroimidazo[1,2-c]quinazoline PI3K Inhibitors: Identification of Copanlisib (BAY 80-6946)

by Scott, William J., Hentemann, Martin F., Rowley, R. Bruce, Bull, Cathy O., Jenkins, Susan, Bullion, Ann M., Johnson, Jeffrey, Redman, Anikó, Robbins, Arthur H., Esler, William, Fracasso, R. Paul, Garrison, Timothy, Hamilton, Mark, Michels, Martin, Wood, Jill E., Wilkie, Dean P., Xiao, Hong, Levy, Joan, Stasik, Enrico, Liu, Ningshu, Schaefer, Martina, Brands, Michael, Lefranc, Julien
Published in ChemMedChem (19.07.2016)

Get full text

Journal Article

BAY 80-6946 is a highly selective intravenous PI3K inhibitor with potent p110α and p110δ activities in tumor cell lines and xenograft models

BAY 80-6946 is a highly selective intravenous PI3K inhibitor with potent p110α and p110δ activities in tumor cell lines and xenograft models

by Liu, Ningshu, Rowley, Bruce R, Bull, Cathy O, Schneider, Claudia, Haegebarth, Andrea, Schatz, Christoph A, Fracasso, Paul R, Wilkie, Dean P, Hentemann, Martin, Wilhelm, Scott M, Scott, William J, Mumberg, Dominik, Ziegelbauer, Karl
Published in Molecular cancer therapeutics (01.11.2013)

Get full text

Journal Article

Constitutively active receptor tyrosine kinases as oncogenes in preclinical models for cancer therapeutics

Constitutively active receptor tyrosine kinases as oncogenes in preclinical models for cancer therapeutics

by Kellar, Kristen A, Lorenzi, Matthew V, Ho, Ching Ping, You, Dan, Wen, Mei-Li, Ryseck, Rolf P, Oppenheimer, Simone, Fink, Brian E, Vite, Gregory D, Rowley, Bruce R, Yu, Chiang, Bol, David K, Lee, Francis Y, Wong, Tai W
Published in Molecular cancer therapeutics (01.06.2006)

Get full text

Journal Article

Tumor development by transgenic expression of a constitutively active insulin-like growth factor I receptor

Tumor development by transgenic expression of a constitutively active insulin-like growth factor I receptor

by CARBONI, Joan M, LEE, Adrian V, HURLBURT, Warren, AIXIN LI, SAUJNIER, Mark, VELAPARTHI, Upender, WANG, Cindy, WEN, Mei-Li, WESTHOUSE, Richard A, WINMAN, Mark, ZIMMERMANN, Kurt, RUPNOW, Brent A, HADSELL, Darryl L, WONG, Tai W, ROWLEY, Bruce R, LEE, Francis Y, BOL, David K, CAMUSO, Amy E, GOTTARDIS, Marco, GREER, Ann F, CHING PING HO
Published in Cancer research (Chicago, Ill.) (01.05.2005)

Get full text

Journal Article

Cyclooxygenase-2 overexpression in the skin of transgenic mice results in suppression of tumor development

Cyclooxygenase-2 overexpression in the skin of transgenic mice results in suppression of tumor development

by BOL, David K, ROWLEY, R. Bruce, HO, Ching-Ping, PILZ, Brigette, DELL, Janet, SWERDEL, Mavis, KIGUCHI, Kaoru, MUGA, Stephanie, KLEIN, Russell, FISCHER, Susan M
Published in Cancer research (Chicago, Ill.) (01.05.2002)

Get full text

Journal Article

Temporal Differences in the Activation of Three Classes of Non- Transmembrane Protein Tyrosine Kinases Following B-Cell Antigen Receptor Surface Engagement

Temporal Differences in the Activation of Three Classes of Non- Transmembrane Protein Tyrosine Kinases Following B-Cell Antigen Receptor Surface Engagement

by Saouaf, Sandra J., Mahajan, Sandeep, Rowley, R. Bruce, Kut, Stephanie A., Fargnoli, Joseph, Burkhardt, Anne L., Tsukada, Satoshi, Witte, Owen N., Bolden, Joseph B.
Published in Proceedings of the National Academy of Sciences - PNAS (27.09.1994)

Get full text

Journal Article

The Src family of tyrosine protein kinases in hemopoietic signal transduction

The Src family of tyrosine protein kinases in hemopoietic signal transduction

by Bolen, J B, Rowley, R B, Spana, C, Tsygankov, A Y
Published in The FASEB journal (01.12.1992)

Get more information

Journal Article

Physical and Functional Interactions between Lyn and p34 Kinases in Irradiated Human B-cell Precursors

Physical and Functional Interactions between Lyn and p34 Kinases in Irradiated Human B-cell Precursors

by Uckun, Fatih M., Tuel-Ahlgren, Lisa, Waddick, Kevin G., Jun, Xiao, Jin, Jizhong, Myers, Dorothea E., Rowley, R. Bruce, Burkhardt, Anne L., Bolen, Joseph B.
Published in The Journal of biological chemistry (15.03.1996)

Get full text

Journal Article

Reconstitution of the B Cell Antigen Receptor Signaling Components in COS Cells ()

Reconstitution of the B Cell Antigen Receptor Signaling Components in COS Cells ()

by Saouaf, Sandra J., Kut, Stephanie A., Fargnoli, Joseph, Rowley, R. Bruce, Bolen, Joseph B., Mahajan, Sandeep
Published in The Journal of biological chemistry (10.11.1995)

Get full text

Journal Article

Abstract B192: Preclinical characterization of BMS-833923 (XL139), a hedgehog (HH) pathway inhibitor in early clinical development

Abstract B192: Preclinical characterization of BMS-833923 (XL139), a hedgehog (HH) pathway inhibitor in early clinical development

by Gendreau, Steven B., Hawkins, Don, Ho, Ching-Ping, Lewin, Anne, Lin, Tara, Merchant, Akil, Rowley, R. Bruce, Wang, Qiuju, Matsui, William, Fargnoli, Joseph
Published in Molecular cancer therapeutics (10.12.2009)

Get full text

Journal Article

Syk protein-tyrosine kinase is regulated by tyrosine-phosphorylated Ig alpha/Ig beta immunoreceptor tyrosine activation motif binding and autophosphorylation

Syk protein-tyrosine kinase is regulated by tyrosine-phosphorylated Ig alpha/Ig beta immunoreceptor tyrosine activation motif binding and autophosphorylation

by Rowley, R B, Burkhardt, A L, Chao, H G, Matsueda, G R, Bolen, J B
Published in The Journal of biological chemistry (12.05.1995)

Get full text

Journal Article

The Syk protein tyrosine kinase can function independently of CD45 or Lck in T cell antigen receptor signaling

The Syk protein tyrosine kinase can function independently of CD45 or Lck in T cell antigen receptor signaling

by Chu, D. H, Spits, H, Peyron, J. F, Rowley, R. B, Bolen, J. B, Weiss, A
Published in The EMBO journal (15.11.1996)

Get full text

Journal Article

Cross-linking of Fc gamma receptor I (Fc gamma RI) and receptor II (Fc gamma RII) on monocytic cells activates a signal transduction pathway common to both Fc receptors that involves the stimulation of p72 Syk protein tyrosine kinase

Cross-linking of Fc gamma receptor I (Fc gamma RI) and receptor II (Fc gamma RII) on monocytic cells activates a signal transduction pathway common to both Fc receptors that involves the stimulation of p72 Syk protein tyrosine kinase

by KIENER, P. A, RANKIN, B. M, BURKHARDT, A. L, SCHIEVEN, G. L, GILLILAND, L. K, ROWLEY, R. B, BOLEN, J. B, LEDBETTER, J. A
Published in The Journal of biological chemistry (15.11.1993)

Get full text

Journal Article

Temporal Activation of Nontransmembrane Protein-tyrosine Kinases following Mast Cell Fc∊RI Engagement (∗)

Temporal Activation of Nontransmembrane Protein-tyrosine Kinases following Mast Cell Fc∊RI Engagement (∗)

by Penhallow, Robert C., Class, Kenneth, Sonoda, Hisaho, Bolen, Joseph B., Rowley, R. Bruce
Published in The Journal of biological chemistry (06.10.1995)

Get full text

Journal Article

Temporal regulation of non-transmembrane protein tyrosine kinase enzyme activity following T cell antigen receptor engagement

Temporal regulation of non-transmembrane protein tyrosine kinase enzyme activity following T cell antigen receptor engagement

by Burkhardt, A L, Stealey, B, Rowley, R B, Mahajan, S, Prendergast, M, Fargnoli, J, Bolen, J B
Published in The Journal of biological chemistry (23.09.1994)

Get full text

Journal Article

Molecular Cloning of Rodent p72Syk

Molecular Cloning of Rodent p72Syk

by Rowley, R. Bruce, Bolen, Joseph B., Fargnoli, Joseph
Published in The Journal of biological chemistry (26.05.1995)

Get full text

Journal Article

Molecular Cloning of Rodent p72

Molecular Cloning of Rodent p72

by R. Bruce Rowley, Joseph B. Bolen, Joseph Fargnoli
Published in The Journal of biological chemistry (26.05.1995)

Get full text

Journal Article

Substituted 2,3-dihydroimidazo[1,2-c]quinazoline derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis

Substituted 2,3-dihydroimidazo[1,2-c]quinazoline derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis

by Rowley, Bruce R, Redman, Aniko, Wood, Jill, Campbell, Ann-Marie, Hentemann, Martin, Scott, William, Bullion, Ann-Marie, Michels, Martin
Year of Publication 22.05.2018

Get full text

Patent

2, 3-dihydroimidazo [1, 2-c] quinazoline substituted derivatives

2, 3-dihydroimidazo [1, 2-c] quinazoline substituted derivatives

by REDEMANN, ANDREAS, CAMPBELL, ANN-MARIE, BULLION, ANN-MARIE, MICHELS, MARTIN, ROWLEY R BRUCE, SCOTT WILLIAM, WOOD JILL, HENTEMANN MARTIN
Year of Publication 03.03.2023

Get full text

Patent

SUBSTITUTED 2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES ASSOCIATED WITH ANGIOGENESIS

SUBSTITUTED 2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES ASSOCIATED WITH ANGIOGENESIS

by ROWLEY, R., BRUCE, CAMPBELL, ANN-MARIE, BULLION, ANN-MARIE, REDMAN, ANIKO, HENTEMANN, MARTIN, MICHELS, MARTIN, SCOTT, WILLIAM, WOOD, JILL
Year of Publication 29.09.2017

Get full text

Patent