Letermovir for Cytomegalovirus Prophylaxis in Hematopoietic-Cell Transplantation
Chemaly, Roy F, Ullmann, Andrew J, Stoelben, Susanne, Richard, Marie Paule, Bornhäuser, Martin, Groth, Christoph, Einsele, Hermann, Silverman, Margarida, Mullane, Kathleen M, Brown, Janice, Nowak, Horst, Kölling, Katrin, Stobernack, Hans P, Lischka, Peter, Zimmermann, Holger, Rübsamen-Schaeff, Helga, Champlin, Richard E, Ehninger, Gerhard
Published in The New England journal of medicine (08.05.2014)
Published in The New England journal of medicine (08.05.2014)
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Pharmacokinetics and Safety of Letermovir Coadministered With Cyclosporine A or Tacrolimus in Healthy Subjects
Kropeit, Dirk, Richter, Oliver, Stobernack, Hans‐Peter, Rübsamen‐Schaeff, Helga, Zimmermann, Holger
Published in Clinical pharmacology in drug development (01.01.2018)
Published in Clinical pharmacology in drug development (01.01.2018)
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First‐in‐Human, Single‐ and Multiple‐Ascending‐Dose, Food‐Effect, and Absolute Bioavailability Trials to Assess the Pharmacokinetics, Safety, and Tolerability of Pritelivir, a Nonnucleoside Helicase‐Primase Inhibitor Against Herpes Simplex Virus in Healthy Subjects
Kropeit, Dirk, Bonsmann, Susanne, Richter, Oliver, McCormick, David, Pausch, Jörg, Sumner, Melanie, Birkmann, Alexander, Zimmermann, Holger, Rübsamen‐Schaeff, Helga
Published in Clinical pharmacology in drug development (01.07.2023)
Published in Clinical pharmacology in drug development (01.07.2023)
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Pharmacokinetics and Safety of Letermovir and Midazolam Coadministration in Healthy Subjects
Kropeit, Dirk, McCormick, David, Erb‐Zohar, Katharina, Stobernack, Hans‐Peter, Zimmermann, Holger, Rübsamen‐Schaeff, Helga
Published in Clinical pharmacology in drug development (01.01.2022)
Published in Clinical pharmacology in drug development (01.01.2022)
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Journal Article
The Effect of Oral Letermovir Administration on the Pharmacokinetics of a Single Oral Dose of P‐Glycoprotein Substrate Digoxin in Healthy Volunteers
Scheuenpflug, Jürgen, Kropeit, Dirk, Erb‐Zohar, Katharina, Theis, Jochen G.W., Stobernack, Hans‐Peter, McCormick, David, Zimmermann, Holger, Rübsamen‐Schaeff, Helga
Published in Clinical pharmacology in drug development (01.01.2022)
Published in Clinical pharmacology in drug development (01.01.2022)
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Structures of ClpP in complex with acyldepsipeptide antibiotics reveal its activation mechanism
Park, Eun Young, Rübsamen-Schaeff, Helga, Lee, Byung-Gil, Jeon, Hyesung, Sung, Kwang Hoon, Paulsen, Holger, Brötz-Oesterhelt, Heike, Song, Hyun Kyu, Lee, Kyung-Eun
Published in Nature structural & molecular biology (01.04.2010)
Published in Nature structural & molecular biology (01.04.2010)
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Pharmacokinetics and safety of letermovir, a novel anti‐human cytomegalovirus drug, in patients with renal impairment
Kropeit, Dirk, Scheuenpflug, Jürgen, Erb‐Zohar, Katharina, Halabi, Atef, Stobernack, Hans‐Peter, Hulskotte, Ellen G. J., Schanke, Arne, Zimmermann, Holger, Rübsamen‐Schaeff, Helga
Published in British journal of clinical pharmacology (01.09.2017)
Published in British journal of clinical pharmacology (01.09.2017)
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Pharmacokinetics and safety of the anti‐human cytomegalovirus drug letermovir in subjects with hepatic impairment
Kropeit, Dirk, McCormick, David, Erb‐Zohar, Katharina, Moiseev, Valentin S., Kobalava, Zhanna D., Stobernack, Hans‐Peter, Zimmermann, Holger, Rübsamen‐Schaeff, Helga
Published in British journal of clinical pharmacology (01.12.2017)
Published in British journal of clinical pharmacology (01.12.2017)
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Journal Article
Preemptive treatment of Cytomegalovirus infection in kidney transplant recipients with letermovir: results of a Phase 2a study
Stoelben, Susanne, Arns, Wolfgang, Renders, Lutz, Hummel, Jürgen, Mühlfeld, Anja, Stangl, Manfred, Fischereder, Michael, Gwinner, Wilfried, Suwelack, Barbara, Witzke, Oliver, Dürr, Michael, Beelen, Dietrich W., Michel, Detlef, Lischka, Peter, Zimmermann, Holger, Rübsamen‐Schaeff, Helga, Budde, Klemens
Published in Transplant international (01.01.2014)
Published in Transplant international (01.01.2014)
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AAA+ chaperones and acyldepsipeptides activate the ClpP protease via conformational control
Gersch, Malte, Famulla, Kirsten, Dahmen, Maria, Göbl, Christoph, Malik, Imran, Richter, Klaus, Korotkov, Vadim S., Sass, Peter, Rübsamen-Schaeff, Helga, Madl, Tobias, Brötz-Oesterhelt, Heike, Sieber, Stephan A.
Published in Nature communications (19.02.2015)
Published in Nature communications (19.02.2015)
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Overcoming fragmentation of health research in Europe: lessons from COVID-19
Sipido, Karin R, Antoñanzas, Fernando, Celis, Julio, Degos, Laurent, Frackowiak, Richard, Fuster, Valentin, Ganten, Detlev, Gay, Steffen, Hofstraat, Hans, Holgate, Stephen T, Krestin, Gabriel, Manns, Michael, Meunier, Francoise, Oertel, Wolfgang, Palkonen, Susanna, Pavalkis, Dainius, Rübsamen-Schaeff, Helga, Smith, Ulf, Stallknecht, Bente Merete, Zima, Tomáš
Published in The Lancet (27.06.2020)
Published in The Lancet (27.06.2020)
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Web Resource
The T cell-selective IL-2 mutant AIC284 mediates protection in a rat model of Multiple Sclerosis
Weishaupt, Andreas, Paulsen, Daniela, Werner, Sandra, Wolf, Nelli, Köllner, Gabriele, Rübsamen-Schaeff, Helga, Hünig, Thomas, Kerkau, Thomas, Beyersdorf, Niklas
Published in Journal of neuroimmunology (15.05.2015)
Published in Journal of neuroimmunology (15.05.2015)
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Helicase-primase inhibitors as the potential next generation of highly active drugs against herpes simplex viruses
Birkmann, Alexander, Hewlett, Guy, Rübsamen-Schaeff, Helga, Zimmermann, Holger
Published in Future Virology (01.10.2011)
Published in Future Virology (01.10.2011)
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Book Review
AAA+ chaperones and acyldepsipeptides activate the ClpP protease via conformational control
Gersch, Malte, Famulla, Kirsten, Dahmen, Maria, Göbl, Christoph, Malik, Imran, Richter, Klaus, Korotkov, Vadim S, Sass, Peter, Rübsamen-Schaeff, Helga, Madl, Tobias, Brötz-Oesterhelt, Heike, Sieber, Stephan A
Published in Nature communications (19.02.2015)
Published in Nature communications (19.02.2015)
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