Pharmacological Rescue of Conditionally Reprogrammed Cystic Fibrosis Bronchial Epithelial Cells
Gentzsch, Martina, Boyles, Susan E, Cheluvaraju, Chaitra, Chaudhry, Imron G, Quinney, Nancy L, Cho, Crescentia, Dang, Hong, Liu, Xuefeng, Schlegel, Richard, Randell, Scott H
Published in American journal of respiratory cell and molecular biology (01.05.2017)
Published in American journal of respiratory cell and molecular biology (01.05.2017)
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Enhanced delivery of peptide-morpholino oligonucleotides with a small molecule to correct splicing defects in the lung
Dang, Yan, van Heusden, Catharina, Nickerson, Veronica, Chung, Felicity, Wang, Yang, Quinney, Nancy L, Gentzsch, Martina, Randell, Scott H, Moulton, Hong M, Kole, Ryszard, Ni, Aiguo, Juliano, Rudolph L, Kreda, Silvia M
Published in Nucleic acids research (21.06.2021)
Published in Nucleic acids research (21.06.2021)
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Airway Epithelial Inflammation In Vitro Augments the Rescue of Mutant CFTR by Current CFTR Modulator Therapies
Gentzsch, Martina, Cholon, Deborah M, Quinney, Nancy L, Martino, Mary E B, Minges, John T, Boyles, Susan E, Guhr Lee, Tara N, Esther, Jr, Charles R, Ribeiro, Carla M P
Published in Frontiers in pharmacology (30.03.2021)
Published in Frontiers in pharmacology (30.03.2021)
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Cystic fibrosis airway inflammation enables elexacaftor/tezacaftor/ivacaftor-mediated rescue of N1303K CFTR mutation
Gentzsch, Martina, Baker, Brooke, Cholon, Deborah M, Kam, Charissa W, McKinzie, Cameron J, Despotes, Katherine A, Boyles, Susan E, Quinney, Nancy L, Esther, Jr, Charles R, Ribeiro, Carla M P
Published in ERJ open research (01.01.2024)
Published in ERJ open research (01.01.2024)
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A Novel Co-Culture Model Reveals Enhanced CFTR Rescue in Primary Cystic Fibrosis Airway Epithelial Cultures with Persistent Pseudomonas aeruginosa Infection
Cholon, Deborah M, Greenwald, Matthew A, Higgs, Matthew G, Quinney, Nancy L, Boyles, Susan E, Meinig, Suzanne L, Minges, John T, Chaubal, Ashlesha, Tarran, Robert, Ribeiro, Carla M P, Wolfgang, Matthew C, Gentzsch, Martina
Published in Cells (Basel, Switzerland) (13.11.2023)
Published in Cells (Basel, Switzerland) (13.11.2023)
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Potentiator ivacaftor abrogates pharmacological correction of ΔF508 CFTR in cystic fibrosis
Cholon, Deborah M, Quinney, Nancy L, Fulcher, M Leslie, Esther, Jr, Charles R, Das, Jhuma, Dokholyan, Nikolay V, Randell, Scott H, Boucher, Richard C, Gentzsch, Martina
Published in Science translational medicine (23.07.2014)
Published in Science translational medicine (23.07.2014)
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Treatment of cystic fibrosis airway cells with CFTR modulators reverses aberrant mucus properties via hydration
Morrison, Cameron B, Shaffer, Kendall M, Araba, Kenza C, Markovetz, Matthew R, Wykoff, Jason A, Quinney, Nancy L, Hao, Shuyu, Delion, Martial F, Flen, Alexis L, Morton, Lisa C, Liao, Jimmy, Hill, David B, Drumm, Mitchell L, O'Neal, Wanda K, Kesimer, Mehmet, Gentzsch, Martina, Ehre, Camille
Published in The European respiratory journal (01.02.2022)
Published in The European respiratory journal (01.02.2022)
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Journal Article
DNAJB12 and Hsp70 triage arrested intermediates of N1303K-CFTR for endoplasmic reticulum-associated autophagy
He, Lihua, Kennedy, Andrew S, Houck, Scott, Aleksandrov, Andrei, Quinney, Nancy L, Cyr-Scully, Alexandra, Cholon, Deborah M, Gentzsch, Martina, Randell, Scott H, Ren, Hong Yu, Cyr, Douglas M
Published in Molecular biology of the cell (01.04.2021)
Published in Molecular biology of the cell (01.04.2021)
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A small-molecule inhibitor and degrader of the RNF5 ubiquitin ligase
Ruan, Jingjing, Liang, Dongdong, Yan, Wenjing, Zhong, Yongwang, Talley, Daniel C, Rai, Ganesha, Tao, Dingyin, LeClair, Christopher A, Simeonov, Anton, Zhang, Yinghua, Chen, Feihu, Quinney, Nancy L, Boyles, Susan E, Cholon, Deborah M, Gentzsch, Martina, Henderson, Mark J, Xue, Fengtian, Fang, Shengyun
Published in Molecular biology of the cell (01.11.2022)
Published in Molecular biology of the cell (01.11.2022)
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Journal Article
Personalised medicine for non-classic cystic fibrosis resulting from rare CFTR mutations
McCravy, Matthew S, Quinney, Nancy L, Cholon, Deborah M, Boyles, Susan E, Jensen, Timothy J, Aleksandrov, Andrei A, Donaldson, Scott H, Noone, Peadar G, Gentzsch, Martina
Published in The European respiratory journal (01.07.2020)
Published in The European respiratory journal (01.07.2020)
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Journal Article
Restoration of R117H CFTR folding and function in human airway cells through combination treatment with VX-809 and VX-770
Gentzsch, Martina, Ren, Hong Y, Houck, Scott A, Quinney, Nancy L, Cholon, Deborah M, Sopha, Pattarawut, Chaudhry, Imron G, Das, Jhuma, Dokholyan, Nikolay V, Randell, Scott H, Cyr, Douglas M
Published in American journal of physiology. Lung cellular and molecular physiology (01.09.2016)
Published in American journal of physiology. Lung cellular and molecular physiology (01.09.2016)
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A PI3Kγ mimetic peptide triggers CFTR gating, bronchodilation, and reduced inflammation in obstructive airway diseases
Ghigo, Alessandra, Murabito, Alessandra, Sala, Valentina, Pisano, Anna Rita, Bertolini, Serena, Gianotti, Ambra, Caci, Emanuela, Montresor, Alessio, Premchandar, Aiswarya, Pirozzi, Flora, Ren, Kai, Della Sala, Angela, Mergiotti, Marco, Richter, Wito, de Poel, Eyleen, Matthey, Michaela, Caldrer, Sara, Cardone, Rosa A, Civiletti, Federica, Costamagna, Andrea, Quinney, Nancy L, Butnarasu, Cosmin, Visentin, Sonja, Ruggiero, Maria Rosaria, Baroni, Simona, Crich, Simonetta Geninatti, Ramel, Damien, Laffargue, Muriel, Tocchetti, Carlo G, Levi, Renzo, Conti, Marco, Lu, Xiao-Yun, Melotti, Paola, Sorio, Claudio, De Rose, Virginia, Facchinetti, Fabrizio, Fanelli, Vito, Wenzel, Daniela, Fleischmann, Bernd K, Mall, Marcus A, Beekman, Jeffrey, Laudanna, Carlo, Gentzsch, Martina, Lukacs, Gergely L, Pedemonte, Nicoletta, Hirsch, Emilio
Published in Science translational medicine (30.03.2022)
Published in Science translational medicine (30.03.2022)
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Journal Article
Nasospheroids permit measurements of CFTR-dependent fluid transport
Guimbellot, Jennifer S, Leach, Justin M, Chaudhry, Imron G, Quinney, Nancy L, Boyles, Susan E, Chua, Michael, Aban, Inmaculada, Jaspers, Ilona, Gentzsch, Martina
Published in JCI insight (16.11.2017)
Published in JCI insight (16.11.2017)
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Journal Article
Thymosin α-1 does not correct F508del-CFTR in cystic fibrosis airway epithelia
Tomati, Valeria, Caci, Emanuela, Ferrera, Loretta, Pesce, Emanuela, Sondo, Elvira, Cholon, Deborah M, Quinney, Nancy L, Boyles, Susan E, Armirotti, Andrea, Ravazzolo, Roberto, Galietta, Luis Jv, Gentzsch, Martina, Pedemonte, Nicoletta
Published in JCI insight (08.02.2018)
Published in JCI insight (08.02.2018)
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Journal Article
Thymosin α-1 does not correct F508del-CFTR in cystic fibrosis airway epithelia
Tomati, Valeria, Caci, Emanuela, Ferrera, Loretta, Pesce, Emanuela, Sondo, Elvira, Cholon, Deborah M, Quinney, Nancy L, Boyles, Susan E, Armirotti, Andrea, Ravazzolo, Roberto, Galietta, Luis Jv, Gentzsch, Martina, Pedemonte, Nicoletta
Published in JCI insight (04.04.2019)
Published in JCI insight (04.04.2019)
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Journal Article
Dysregulated Airway Host Defense in Hyper IgE Syndrome due to STAT3 Mutations
Sun, Ling, Walls, Samantha A, Dang, Hong, Quinney, Nancy L, Sears, Patrick R, Sadritabrizi, Taraneh, Hasegawa, Koichi, Okuda, Kenichi, Asakura, Takanori, Chang, Xiuya, Zheng, Meiqi, Mikami, Yu, Dizmond, Felicia U, Danilova, Daniela, Zhou, Lynn, Deshmukh, Anshulika, Cholon, Deborah M, Radicioni, Giorgia, Rogers, Troy D, Kissner, William J, Markovetz, Matthew R, Guhr Lee, Tara N, Gutay, Mark I, Esther, Charles R, Chua, Michael, Grubb, Barbara R, Ehre, Camille, Kesimer, Mehmet, Hill, David B, Ostrowski, Lawrence E, Button, Brian, Gentzsch, Martina, Robinson, Chevalia, Olivier, Kenneth N, Freeman, Alexandra F, Randell, Scott H, O'Neal, Wanda K, Boucher, Richard C, Chen, Gang
Published in bioRxiv (15.08.2024)
Published in bioRxiv (15.08.2024)
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A Novel Co-Culture Model Reveals Enhanced CFTR Rescue in Primary Cystic Fibrosis Airway Epithelial Cultures with Persistent IPseudomonas aeruginosa/I Infection
Cholon, Deborah M, Greenwald, Matthew A, Higgs, Matthew G, Quinney, Nancy L, Boyles, Susan E, Meinig, Suzanne L, Minges, John T, Chaubal, Ashlesha, Tarran, Robert, Ribeiro, Carla M. P, Wolfgang, Matthew C, Gentzsch, Ma
Published in Cells (Basel, Switzerland) (01.11.2023)
Published in Cells (Basel, Switzerland) (01.11.2023)
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