Targeting progesterone signaling prevents metastatic ovarian cancer
Kim, Olga, Park, Eun Young, Kwon, Sun Young, Shin, Sojin, Emerson, Robert E., Shin, Yong-Hyun, DeMayo, Francesco J., Lydon, John P., Coffey, Donna M., Hawkins, Shannon M., Quilliam, Lawrence A., Cheon, Dong-Joo, Fernández, Facundo M., Nephew, Kenneth P., Karpf, Adam R., Widschwendter, Martin, Sood, Anil K., Bast, Robert C., Godwin, Andrew K., Miller, Kathy D., Cho, Chi-Heum, Kim, Jaeyeon
Published in Proceedings of the National Academy of Sciences - PNAS (15.12.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (15.12.2020)
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Journal Article
Rap1 Promotes Cell Spreading by Localizing Rac Guanine Nucleotide Exchange Factors
Arthur, William T., Quilliam, Lawrence A., Cooper, Jonathan A.
Published in The Journal of cell biology (11.10.2004)
Published in The Journal of cell biology (11.10.2004)
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Journal Article
Crk proteins transduce FGF signaling to promote lens fiber cell elongation
Collins, Tamica N, Mao, Yingyu, Li, Hongge, Bouaziz, Michael, Hong, Angela, Feng, Gen-Sheng, Wang, Fen, Quilliam, Lawrence A, Chen, Lin, Park, Taeju, Curran, Tom, Zhang, Xin
Published in eLife (23.01.2018)
Published in eLife (23.01.2018)
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Journal Article
Rheb Binds Tuberous Sclerosis Complex 2 (TSC2) and Promotes S6 Kinase Activation in a Rapamycin- and Farnesylation-dependent Manner
Castro, Ariel F., Rebhun, John F., Clark, Geoffrey J., Quilliam, Lawrence A.
Published in The Journal of biological chemistry (29.08.2003)
Published in The Journal of biological chemistry (29.08.2003)
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Journal Article
A Novel HRAS Mutation Independently Contributes to Left Ventricular Hypertrophy in a Family with a Known MYH7 Mutation
Sana, Maria Elena, Quilliam, Lawrence A, Spitaleri, Andrea, Pezzoli, Laura, Marchetti, Daniela, Lodrini, Chiara, Candiago, Elisabetta, Lincesso, Anna Rita, Ferrazzi, Paolo, Iascone, Maria
Published in PloS one (21.12.2016)
Published in PloS one (21.12.2016)
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Journal Article
Rap1 GTPase activation and barrier enhancement in rpe inhibits choroidal neovascularization in vivo
Wittchen, Erika S, Nishimura, Eiichi, McCloskey, Manabu, Wang, Haibo, Quilliam, Lawrence A, Chrzanowska-Wodnicka, Magdalena, Hartnett, M Elizabeth
Published in PloS one (10.09.2013)
Published in PloS one (10.09.2013)
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Journal Article
Mammalian Target of Rapamycin Complex 1 (mTORC1) Enhances Bortezomib-induced Death in Tuberous Sclerosis Complex (TSC)-null Cells by a c-MYC-dependent Induction of the Unfolded Protein Response
Babcock, Justin T., Nguyen, Hoa B., He, Yujun, Hendricks, Jeremiah W., Wek, Ronald C., Quilliam, Lawrence A.
Published in The Journal of biological chemistry (31.05.2013)
Published in The Journal of biological chemistry (31.05.2013)
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Journal Article
Rap1b facilitates NK cell functions via IQGAP1-mediated signalosomes
Awasthi, Aradhana, Samarakoon, Asanga, Chu, Haiyan, Kamalakannan, Rajasekaran, Quilliam, Lawrence A, Chrzanowska-Wodnicka, Magdalena, White, 2nd, Gilbert C, Malarkannan, Subramaniam
Published in The Journal of experimental medicine (30.08.2010)
Published in The Journal of experimental medicine (30.08.2010)
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Journal Article
Human TSC-associated renal angiomyolipoma cells are hypersensitive to ER stress
Siroky, Brian J, Yin, Hong, Babcock, Justin T, Lu, Lu, Hellmann, Anna R, Dixon, Bradley P, Quilliam, Lawrence A, Bissler, John J
Published in American journal of physiology. Renal physiology (15.09.2012)
Published in American journal of physiology. Renal physiology (15.09.2012)
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Journal Article
E-cadherin dis-engagement activates the Rap1 GTPase
Asuri, Sirisha, Yan, Jingliang, Paranavitana, Nivanka C., Quilliam, Lawrence A.
Published in Journal of cellular biochemistry (01.11.2008)
Published in Journal of cellular biochemistry (01.11.2008)
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Journal Article
Rap1a Null Mice Have Altered Myeloid Cell Functions Suggesting Distinct Roles for the Closely Related Rap1a and 1b Proteins
Li, Yu, Yan, Jingliang, De, Pradip, Chang, Hua-Chen, Yamauchi, Akira, Christopherson, Kent W., II, Paranavitana, Nivanka C, Peng, Xiaodong, Kim, Chaekyun, Munugulavadla, Veerendra, Kapur, Reuben, Chen, Hanying, Shou, Weinian, Stone, James C, Kaplan, Mark H, Dinauer, Mary C, Durden, Donald L, Quilliam, Lawrence A
Published in The Journal of immunology (1950) (15.12.2007)
Published in The Journal of immunology (1950) (15.12.2007)
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Journal Article
The RAP1 Guanine Nucleotide Exchange Factor Epac2 Couples Cyclic AMP and Ras Signals at the Plasma Membrane
Li, Yu, Asuri, Sirisha, Rebhun, John F., Castro, Ariel F., Paranavitana, Nivanka C., Quilliam, Lawrence A.
Published in The Journal of biological chemistry (03.02.2006)
Published in The Journal of biological chemistry (03.02.2006)
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Journal Article
Chemoattractant-Stimulated Rac Activation in Wild-Type and Rac2-Deficient Murine Neutrophils: Preferential Activation of Rac2 and Rac2 Gene Dosage Effect on Neutrophil Functions
Li, Shijun, Yamauchi, Akira, Marchal, Christophe C, Molitoris, Jason K, Quilliam, Lawrence A, Dinauer, Mary C
Published in The Journal of immunology (1950) (01.11.2002)
Published in The Journal of immunology (1950) (01.11.2002)
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Journal Article
Retinal pigment epithelial cell expression of active Rap 1a by scAAV2 inhibits choroidal neovascularization
Wang, Haibo, Han, Xiaokun, Bretz, Colin A, Becker, Silke, Gambhir, Deeksha, Smith, George W, Samulski, R Jude, Wittchen, Erika S, Quilliam, Lawrence A, Chrzanowska-Wodnicka, Magdalena, Hartnett, M Elizabeth
Published in Molecular therapy. Methods & clinical development (2016)
Published in Molecular therapy. Methods & clinical development (2016)
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Journal Article