Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted stat6 gene
SHIMODA, K, VAN DEURSEN, J, DOHERTY, P. C, GROSVELD, G, PAUL, W. E, IHLE, J. N, SANGSTER, M. Y, SARAWAR, S. R, CARSON, R. T, TRIPP, R. A, CHU, C, QUELLE, F. W, NOSAKA, T, VIGNALI, D. A. A
Published in Nature (London) (18.04.1996)
Published in Nature (London) (18.04.1996)
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Journal Article
JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin
Witthuhn, Bruce A., Quelle, Frederick W., Silvennoinen, Olli, Yi, Taolin, Tang, Bo, Miura, Osamu, Ihle, James N.
Published in Cell (30.07.1993)
Published in Cell (30.07.1993)
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Signaling through the hematopoietic cytokine receptors
Ihle, J N, Witthuhn, B A, Quelle, F W, Yamamoto, K, Silvennoinen, O
Published in Annual review of immunology (01.01.1995)
Published in Annual review of immunology (01.01.1995)
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Journal Article
Association and Activation of Jak-Tyk Kinases by CNTF-LIF-OSM-IL-6 β Receptor Components
Stahl, Neil, Boulton, Teri G., Farruggella, Thomas, Ip, Nancy Y., Davis, Sam, Witthuhn, Bruce A., Quelle, Frederick W., Silvennoinen, Olli, Barbieri, Giovanna, Pellegrini, Sandra, Ihle, James N., Yancopoulos, George D.
Published in Science (American Association for the Advancement of Science) (07.01.1994)
Published in Science (American Association for the Advancement of Science) (07.01.1994)
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Journal Article
Structure of the Murine Jak2 Protein-Tyrosine Kinase and its Role in Interleukin 3 Signal Transduction
Silvennoinen, Olli, Witthuhn, Bruce A., Quelle, Frederick W., Cleveland, John L., Yi, Taolin, Ihle, James N.
Published in Proceedings of the National Academy of Sciences - PNAS (15.09.1993)
Published in Proceedings of the National Academy of Sciences - PNAS (15.09.1993)
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Journal Article
Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis
Quelle, Frederick W., Shimoda, Kazuya, Thierfelder, William, Fischer, Carrie, Kim, Ann, Ruben, Steven M., Cleveland, John L., Pierce, Jacalyn H., Keegan, Achsah D., Nelms, Keats, Paul, William E., Ihle, James N.
Published in Molecular and Cellular Biology (01.06.1995)
Published in Molecular and Cellular Biology (01.06.1995)
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Journal Article
Erythropoietin induces activation of Stat5 through association with specific tyrosines on the receptor that are not required for a mitogenic response
Quelle, Frederick W., Wang, Demin, Nosaka, Tetsuya, Thierfelder, William E., Stravopodis, Dimitrios, Weinstein, Yacob, Ihle, James N.
Published in Molecular and Cellular Biology (01.04.1996)
Published in Molecular and Cellular Biology (01.04.1996)
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Journal Article
Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-& gamma; signal transduction pathway
Watling, Diane, Guschin, Dmitry, Müller, Mathias, Silvennoinen, Olli, Witthuhn, Bruce A, Quelle, Frederick W, Rogers, Neil C, Schindler, Chris, Stark, George R, Ihle, James N, Kerr, lan M
Published in Nature (London) (11.11.1993)
Published in Nature (London) (11.11.1993)
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Journal Article
Interleukin‐3 signals through multiple isoforms of Stat5
Azam, M., Erdjument‐Bromage, H., Kreider, B.L., Xia, M., Quelle, F., Basu, R., Saris, C., Tempst, P., Ihle, J.N., Schindler, C.
Published in The EMBO journal (03.04.1995)
Published in The EMBO journal (03.04.1995)
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Journal Article
Cytokine rescue of p53-dependent apoptosis and cell cycle arrest is mediated by distinct Jak kinase signaling pathways
Quelle, F W, Wang, J, Feng, J, Wang, D, Cleveland, J L, Ihle, J N, Zambetti, G P
Published in Genes & development (15.04.1998)
Published in Genes & development (15.04.1998)
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Journal Article
Stat4, a novel gamma interferon activation site-binding protein expressed in early myeloid differentiation
Yamamoto, K, Quelle, F W, Thierfelder, W E, Kreider, B L, Gilbert, D J, Jenkins, N A, Copeland, N G, Silvennoinen, O, Ihle, J N
Published in Molecular and Cellular Biology (01.07.1994)
Published in Molecular and Cellular Biology (01.07.1994)
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Journal Article
Distribution of the Mammalian Stat Gene Family in Mouse Chromosomes
Copeland, Neal G., Gilbert, Debra J., Schindler, Chris, Zhong, Zhong, Wen, Zilong, Darnell, James E., Mui, Alice L.-F., Miyajima, Atsushi, Quelle, Frederick W., Ihle, James N., Jenkins, Nancy A.
Published in Genomics (San Diego, Calif.) (01.09.1995)
Published in Genomics (San Diego, Calif.) (01.09.1995)
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Journal Article
Signaling by the cytokine receptor superfamily: JAKs and STATs
Ihle, James N., Witthuhn, Bruce A., Quelle, Frederick W., Yamamoto, Koh, Thierfelder, William E., Kreider, Brent, Silvennoinen, Olli
Published in Trends in Biochemical Sciences (01.05.1994)
Published in Trends in Biochemical Sciences (01.05.1994)
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JAK2 associates with the beta c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region
Quelle, F W, Sato, N, Witthuhn, B A, Inhorn, R C, Eder, M, Miyajima, A, Griffin, J D, Ihle, J N
Published in Molecular and Cellular Biology (01.07.1994)
Published in Molecular and Cellular Biology (01.07.1994)
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