Vitamin D Receptor Activation Down-regulates the Small Heterodimer Partner and Increases CYP7A1 to Lower Cholesterol
Chow, Edwin C.Y, Magomedova, Lilia, Quach, Holly P, Patel, Rucha, Durk, Matthew R, Fan, Jianghong, Maeng, Han-Joo, Irondi, Kamdi, Anakk, Sayeepriyadarshini, Moore, David D, Cummins, Carolyn L, Pang, K. Sandy
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2014)
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2014)
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Disrupted Murine Gut-to-Human Liver Signaling Alters Bile Acid Homeostasis in Humanized Mouse Liver Models
Chow, Edwin C Y, Quach, Holly P, Zhang, Yueping, Wang, Jason Z Y, Evans, David C, Li, Albert P, Silva, Jose, Tirona, Rommel G, Lai, Yurong, Pang, K Sandy
Published in The Journal of pharmacology and experimental therapeutics (01.01.2017)
Published in The Journal of pharmacology and experimental therapeutics (01.01.2017)
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Journal Article
Temporal changes in tissue 1α,25-dihydroxyvitamin D3, vitamin D receptor target genes, and calcium and PTH levels after 1,25(OH)2D3 treatment in mice
Chow, Edwin C Y, Quach, Holly P, Vieth, Reinhold, Pang, K Sandy
Published in American journal of physiology: endocrinology and metabolism (01.05.2013)
Published in American journal of physiology: endocrinology and metabolism (01.05.2013)
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Journal Article
Highlighting Vitamin D Receptor-Targeted Activities of 1 α ,25-Dihydroxyvitamin D 3 in Mice via Physiologically Based Pharmacokinetic-Pharmacodynamic Modeling
Yang, Qi Joy, Bukuroshi, Paola, Quach, Holly P, Chow, Edwin C Y, Pang, K Sandy
Published in Drug metabolism and disposition (01.01.2018)
Published in Drug metabolism and disposition (01.01.2018)
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Potencies of vitamin D analogs, 1α‐hydroxyvitamin D3, 1α‐hydroxyvitamin D2 and 25‐hydroxyvitamin D3, in lowering cholesterol in hypercholesterolemic mice in vivo
Quach, Holly P., Dzekic, Tamara, Bukuroshi, Paola, Pang, K. Sandy
Published in Biopharmaceutics & drug disposition (01.04.2018)
Published in Biopharmaceutics & drug disposition (01.04.2018)
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Journal Article
Highlighting Vitamin D Receptor-Targeted Activities of 1α,25-Dihydroxyvitamin D3 in Mice via Physiologically Based Pharmacokinetic-Pharmacodynamic Modeling
Yang, Qi Joy, Bukuroshi, Paola, Quach, Holly P, Chow, Edwin C Y, Pang, K Sandy
Published in Drug metabolism and disposition (01.01.2018)
Published in Drug metabolism and disposition (01.01.2018)
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Journal Article
Potencies of vitamin D analogs, 1α-hydroxyvitamin D 3 , 1α-hydroxyvitamin D 2 and 25-hydroxyvitamin D 3 , in lowering cholesterol in hypercholesterolemic mice in vivo
Quach, Holly P, Dzekic, Tamara, Bukuroshi, Paola, Pang, K Sandy
Published in Biopharmaceutics & drug disposition (01.04.2018)
Published in Biopharmaceutics & drug disposition (01.04.2018)
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Journal Article
PKPD modelling to predict altered disposition of 1α,25‐dihydroxyvitamin D3 in mice due to dose‐dependent regulation of CYP27B1 on synthesis and CYP24A1 on degradation
Quach, Holly P, Yang, Qi J, Chow, Edwin C, Mager, Donald E, Hoi, Stacie Y, Pang, K Sandy
Published in British journal of pharmacology (01.07.2015)
Published in British journal of pharmacology (01.07.2015)
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Alterations in gene expression in vitamin D‐deficiency: Down‐regulation of liver Cyp7a1 and renal Oat3 in mice
Quach, Holly P., Noh, Keumhan, Hoi, Stacie Y., Bruinsma, Adrie, Groothuis, Geny M.M., Li, Albert P., Chow, Edwin C.Y., Pang, K. Sandy
Published in Biopharmaceutics & drug disposition (01.02.2018)
Published in Biopharmaceutics & drug disposition (01.02.2018)
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Functional Integrity of the Chimeric (Humanized) Mouse Liver: Enzyme Zonation, Physiologic Spaces, and Hepatic Enzymes and Transporters
Chow, Edwin C Y, Wang, Jason Z Ya, Quach, Holly P, Tang, Hui, Evans, David C, Li, Albert P, Silva, Jose, Pang, K Sandy
Published in Drug metabolism and disposition (01.09.2016)
Published in Drug metabolism and disposition (01.09.2016)
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Journal Article
Effects of 1α,25-Dihydroxyvitamin D3, the Natural Vitamin D Receptor Ligand, on the Pharmacokinetics of Cefdinir and Cefadroxil, Organic Anion Transporter Substrates, in Rat
Kim, Yu Chul, Kim, In-Bong, Noh, Chi-Kyoung, Quach, Holly P., Yoon, In-Soo, Chow, Edwin C.Y., Kim, Myungsoo, Jin, Hyo-Eon, Cho, Kwan Hyung, Chung, Suk-Jae, Pang, K. Sandy, Maeng, Han-Joo
Published in Journal of pharmaceutical sciences (01.11.2014)
Published in Journal of pharmaceutical sciences (01.11.2014)
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Journal Article
Highlighting Vitamin D Receptor–Targeted Activities of 1α,25-Dihydroxyvitamin D^sub 3^ in Mice via Physiologically Based Pharmacokinetic-Pharmacodynamic Modeling
Yang, Qi Joy, Bukuroshi, Paola, Quach, Holly P, Chow, Edwin C Y, Pang, K Sandy
Published in Drug metabolism and disposition (01.01.2018)
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Published in Drug metabolism and disposition (01.01.2018)
Journal Article
Effects of 1α,25-Dihydroxyvitamin D 3 , the Natural Vitamin D Receptor Ligand, on the Pharmacokinetics of Cefdinir and Cefadroxil, Organic Anion Transporter Substrates, in Rat
Kim, Yu Chul, Kim, In-Bong, Noh, Chi-Kyoung, Quach, Holly P., Yoon, In-Soo, Chow, Edwin C.Y., Kim, Myungsoo, Jin, Hyo-Eon, Cho, Kwan Hyung, Chung, Suk-Jae, Pang, K. Sandy, Maeng, Han-Joo
Published in Journal of pharmaceutical sciences (01.11.2014)
Published in Journal of pharmaceutical sciences (01.11.2014)
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Journal Article
PKPD modelling to predict altered disposition of 1[alpha],25-dihydroxyvitamin D3 in mice due to dose-dependent regulation of CYP27B1 on synthesis and CYP24A1 on degradation
Quach, Holly P, Yang, Qi J, Chow, Edwin C, Mager, Donald E, Hoi, Stacie Y, Pang, K Sandy
Published in British journal of pharmacology (01.07.2015)
Published in British journal of pharmacology (01.07.2015)
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Journal Article
PKPD modelling to predict altered disposition of 1α,25‐dihydroxyvitamin D 3 in mice due to dose‐dependent regulation of CYP27B1 on synthesis and CYP24A1 on degradation
Quach, Holly P, Yang, Qi J, Chow, Edwin C, Mager, Donald E, Hoi, Stacie Y, Pang, K Sandy
Published in British journal of pharmacology (01.07.2015)
Published in British journal of pharmacology (01.07.2015)
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Journal Article