Function through Synthesis-Informed Design
Wender, Paul A, Quiroz, Ryan V, Stevens, Matthew C
Published in Accounts of chemical research (17.03.2015)
Published in Accounts of chemical research (17.03.2015)
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Journal Article
Scalable synthesis of bryostatin 1 and analogs, adjuvant leads against latent HIV
Wender, Paul A., Hardman, Clayton T., Ho, Stephen, Jeffreys, Matthew S., Maclaren, Jana K., Quiroz, Ryan V., Ryckbosch, Steven M., Shimizu, Akira J., Sloane, Jack L., Stevens, Matthew C.
Published in Science (American Association for the Advancement of Science) (13.10.2017)
Published in Science (American Association for the Advancement of Science) (13.10.2017)
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Journal Article
Development of a Flexible and Robust Synthesis of Tetrahydrofuro[3,4‑b]furan Nucleoside Analogues
Candito, David A, Ye, Yingchun, Quiroz, Ryan V, Reutershan, Michael H, Witter, David, Gadamsetty, Surendra B, Li, Hongming, Saurí, Josep, Schneider, Sebastian E, Lam, Yu-hong, Palte, Rachel L
Published in Journal of organic chemistry (02.04.2021)
Published in Journal of organic chemistry (02.04.2021)
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Journal Article
The Discovery of Two Novel Classes of 5,5-Bicyclic Nucleoside-Derived PRMT5 Inhibitors for the Treatment of Cancer
Quiroz, Ryan V, Reutershan, Michael H, Schneider, Sebastian E, Sloman, David, Lacey, Brian M, Swalm, Brooke M, Yeung, Charles S, Gibeau, Craig, Spellman, Daniel S, Rankic, Danica A, Chen, Dapeng, Witter, David, Linn, Doug, Munsell, Erik, Feng, Guo, Xu, Haiyan, Hughes, Jonathan M. E, Lim, Jongwon, Saurí, Josep, Geddes, Kristin, Wan, Murray, Mansueto, My Sam, Follmer, Nicole E, Fier, Patrick S, Siliphaivanh, Phieng, Daublain, Pierre, Palte, Rachel L, Hayes, Robert P, Lee, Sandra, Kawamura, Shuhei, Silverman, Steven, Sanyal, Sulagna, Henderson, Timothy J, Ye, Yingchun, Gao, Yuanwei, Nicholson, Benjamin, Machacek, Michelle R
Published in Journal of medicinal chemistry (08.04.2021)
Published in Journal of medicinal chemistry (08.04.2021)
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Journal Article
Structural complexity through multicomponent cycloaddition cascades enabled by dual-purpose, reactivity regenerating 1,2,3-triene equivalents
Wender, Paul A., Fournogerakis, Dennis N., Jeffreys, Matthew S., Quiroz, Ryan V., Inagaki, Fuyuhiko, Pfaffenbach, Magnus
Published in Nature chemistry (01.05.2014)
Published in Nature chemistry (01.05.2014)
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Journal Article
ChemInform Abstract: Structural Complexity Through Multicomponent Cycloaddition Cascades Enabled by Dual-Purpose, Reactivity Regenerating 1,2,3-Triene Equivalents
Wender, Paul A., Fournogerakis, Dennis N., Jeffreys, Matthew S., Quiroz, Ryan V., Inagaki, Fuyuhiko, Pfaffenbach, Magnus
Published in ChemInform (07.10.2014)
Published in ChemInform (07.10.2014)
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Journal Article
PRMT5 억제제
CANDITO DAVID A, QUIROZ RYAN, WITTER DAVID, HUANG CHUNHUI, SILIPHAIVANH PHIENG, HUGHES JONATHAN M. E, HENDERSON TIMOTHY J, YE YINGCHUN, SCHNEIDER SEBASTIAN, KAWAMURA SHUHEI, YEUNG CHARLES S, FIER PATRICK S, WAN MURRAY, REUTERSHAN MICHAEL H, RAHALI HOUCINE, SANYAL SULAGNA, GIBEAU CRAIG, PAPARIN JEAN LAURENT, SILVERMAN STEVEN M, MACHACEK MICHELLE, SLOMAN DAVID L
Year of Publication 27.04.2021
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Year of Publication 27.04.2021
Patent
Function through bio-inspired, synthesis-informed design: step-economical syntheses of designed kinase inhibitors†Dedicated to Max Malacria, a friend and scholar whose science and creative contributions to step-economical synthesis have inspired us all and moved the field closer to the ideal.‡Electronic supplementary information (ESI) available: Synthetic procedures and spectral data. See DOI: 10.1039/c4qo00228hClick here for additional data file
Wender, Paul A, Axtman, Alison D, Golden, Jennifer E, Kee, Jung-Min, Sirois, Lauren E, Quiroz, Ryan V, Stevens, Matthew C
Published in Organic chemistry frontiers an international journal of organic chemistry (29.12.2014)
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Published in Organic chemistry frontiers an international journal of organic chemistry (29.12.2014)
Journal Article
Function through bio-inspired, synthesis-informed design: step-economical syntheses of designed kinase inhibitors† †Dedicated to Max Malacria, a friend and scholar whose science and creative contributions to step-economical synthesis have inspired us all and moved the field closer to the ideal. ‡ ‡Electronic supplementary information (ESI) available: Synthetic procedures and spectral data. See DOI: 10.1039/c4qo00228h Click here for additional data file
Wender, Paul A., Axtman, Alison D., Golden, Jennifer E., Kee, Jung-Min, Sirois, Lauren E., Quiroz, Ryan V., Stevens, Matthew C.
Published in Organic chemistry frontiers an international journal of organic chemistry (06.10.2014)
Published in Organic chemistry frontiers an international journal of organic chemistry (06.10.2014)
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Journal Article
PRMT5 inhibitors
Reutershan, Michael H, Machacek, Michelle, Quiroz, Ryan, Schneider, Sebastian, Kawamura, Shuhei, Yeung, Charles S, Siliphaivanh, Phieng, Witter, David, Ye, Yingchun
Year of Publication 28.05.2024
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Year of Publication 28.05.2024
Patent
BRYOSTATIN COMPOUNDS AND METHODS OF PREPARING THE SAME
Ho, Stephen, Shimizu, Akira, Sloane, Jack, Wender, Paul, Quiroz, Ryan, Stevens, Matthew C, Hardman, Clayton, Ryckbosch, Steven, Jeffreys, Matthew S
Year of Publication 11.04.2024
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Year of Publication 11.04.2024
Patent
Bryostatin compounds and methods of preparing the same
Ho, Stephen, Shimizu, Akira, Sloane, Jack, Wender, Paul, Quiroz, Ryan, Stevens, Matthew C, Hardman, Clayton, Ryckbosch, Steven, Jeffreys, Matthew S
Year of Publication 05.09.2023
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Year of Publication 05.09.2023
Patent
PNU ANTHRACYCLINE DERIVATIVES AND METHODS OF USE THEREOF
QUIROZ, Ryan, MORALES, Christian L, WEN, Xin, TONG, Ling, LANG, Simon B, CHEN, Sijie, FLYGARE, John A, SEGANISH, W. Michael, JOHNSON, Rebecca Elizabeth
Year of Publication 02.05.2024
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Year of Publication 02.05.2024
Patent
IL4I1 INHIBITORS AND METHODS OF USE
HOPKINS, BRETT A, CASH, BRANDON D, LIU, PING, YAN, XIN, LARSEN, MATTHEW A, QUIROZ, RYAN, WHITE, CATHERINE M, HAIDLE, ANDREW M, ZHENG, XIAO MEI, SANYAL, SULAGNA, GIAMBASU, GEORGE MADALIN, LESBURG, CHARLES A
Year of Publication 29.08.2024
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Year of Publication 29.08.2024
Patent
PNU ANTHRACYCLINE-DERIVED LINKER-PAYLOADS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF
QUIROZ, Ryan, MORALES, Christian L, TONG, Ling, LANG, Simon B, ZEPEDA, Nancy S, CHARATI, Manoj B, FLYGARE, John A, DU REGENS, Juana, SEGANISH, W. Michael, JOHNSON, Rebecca Elizabeth
Year of Publication 02.08.2024
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Year of Publication 02.08.2024
Patent
PNU ANTHRACYCLINE-DERIVED LINKER-PAYLOADS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF
QUIROZ, Ryan, MORALES, Christian L, TONG, Ling, LANG, Simon B, ZEPEDA, Nancy S, CHARATI, Manoj B, FLYGARE, John A, DU REGENS, Juana, SEGANISH, W. Michael, JOHNSON, Rebecca Elizabeth
Year of Publication 27.06.2024
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Year of Publication 27.06.2024
Patent