Inhibition of LSD1 reduces herpesvirus infection, shedding, and recurrence by promoting epigenetic suppression of viral genomes
Hill, James M, Quenelle, Debra C, Cardin, Rhonda D, Vogel, Jodi L, Clement, Christian, Bravo, Fernando J, Foster, Timothy P, Bosch-Marce, Marta, Raja, Priya, Lee, Jennifer S, Bernstein, David I, Krause, Philip R, Knipe, David M, Kristie, Thomas M
Published in Science translational medicine (03.12.2014)
Published in Science translational medicine (03.12.2014)
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Journal Article
Efficacy of CMX001 against Herpes Simplex Virus Infections in Mice and Correlations with Drug Distribution Studies
Quenelle, Debra C., Lampert, Bernhardt, Collins, Deborah J., Rice, Terri L., Painter, George R., Kern, Earl R.
Published in The Journal of infectious diseases (15.11.2010)
Published in The Journal of infectious diseases (15.11.2010)
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Synergistic Efficacy of the Combination of ST-246 with CMX001 against Orthopoxviruses
QUENELLE, Debra C, PRICHARD, Mark N, KEITH, Kathy A, HRUBY, Dennis E, JORDAN, Robert, PAINTER, George R, ROBERTSON, Alice, KERN, Earl R
Published in Antimicrobial Agents and Chemotherapy (01.11.2007)
Published in Antimicrobial Agents and Chemotherapy (01.11.2007)
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Journal Article
Efficacy of Delayed Treatment with ST-246 Given Orally against Systemic Orthopoxvirus Infections in Mice
QUENELLE, Debra C, BULLER, R. M. L, PARKER, Scott, KEITH, Kathy A, HRUBY, Dennis E, JORDAN, Robert, KERN, Earl R
Published in Antimicrobial Agents and Chemotherapy (01.02.2007)
Published in Antimicrobial Agents and Chemotherapy (01.02.2007)
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Preclinical Evaluation of a Genetically Engineered Herpes Simplex Virus Expressing Interleukin-12
MARKERT, James M, CODY, James J, CARTNER, Samuel C, YANCEY GILLESPIE, G, WHITLEY, Richard J, PARKER, Jacqueline N, COLEMAN, Jennifer M, PRICE, Kathleen H, KERN, Earl R, QUENELLE, Debra C, LAKEMAN, Alfred D, SCHOEB, Trenton R, PALMER, Cheryl A
Published in Journal of Virology (01.05.2012)
Published in Journal of Virology (01.05.2012)
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Inhibition of Herpesvirus Replication by 5-Substituted 4′-Thiopyrimidine Nucleosides
PRICHARD, Mark N, QUENELLE, Debra C, SECRIST, John A, KERN, Earl R, HARTLINE, Caroll B, HARDEN, Emma A, JEFFERSON, Geraldine, FREDERICK, Samuel L, DAILY, Shannon L, WHITLEY, Richard J, TIWARI, Kamal N, MADDRY, Joseph A
Published in Antimicrobial Agents and Chemotherapy (01.12.2009)
Published in Antimicrobial Agents and Chemotherapy (01.12.2009)
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Oral Activity of a Methylenecyclopropane Analog, Cyclopropavir, in Animal Models for Cytomegalovirus Infections
Kern, Earl R, Bidanset, Deborah J, Hartline, Caroll B, Yan, Zhaohua, Zemlicka, Jiri, Quenelle, Debra C
Published in Antimicrobial Agents and Chemotherapy (01.12.2004)
Published in Antimicrobial Agents and Chemotherapy (01.12.2004)
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Treatment of Vaccinia and Cowpox Virus Infections in Mice with CMX001 and ST-246
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Book Review
Effect of Oral Treatment with Hexadecyloxypropyl-[(S)-9-(3-Hydroxy-2- Phosphonylmethoxypropyl)Adenine] [(S)-HPMPA] or Octadecyloxyethyl-(S)-HPMPA on Cowpox or Vaccinia Virus Infections in Mice
QUENELLE, Debra C, COLLINS, Deborah J, HERROD, Bridgett P, KEITH, Kathy A, TRAHAN, Julissa, BEADLE, James R, HOSTETLER, Karl Y, KERN, Earl R
Published in Antimicrobial Agents and Chemotherapy (01.11.2007)
Published in Antimicrobial Agents and Chemotherapy (01.11.2007)
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Activities of Certain 5-Substituted 4′-Thiopyrimidine Nucleosides against Orthopoxvirus Infections
KERN, Earl R, PRICHARD, Mark N, QUENELLE, Debra C, KEITH, Kathy A, TIWARI, Kamal N, MADDRY, Joseph A, SECRIST, John A
Published in Antimicrobial Agents and Chemotherapy (01.02.2009)
Published in Antimicrobial Agents and Chemotherapy (01.02.2009)
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Isolation and characterization of cidofovir resistant vaccinia viruses
Becker, Marie N, Obraztsova, Maria, Kern, Earl R, Quenelle, Debra C, Keith, Kathy A, Prichard, Mark N, Luo, Ming, Moyer, Richard W
Published in Virology journal (14.05.2008)
Published in Virology journal (14.05.2008)
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Efficacy of pritelivir and acyclovir in the treatment of herpes simplex virus infections in a mouse model of herpes simplex encephalitis
Quenelle, Debra C., Birkmann, Alexander, Goldner, Thomas, Pfaff, Tamara, Zimmermann, Holger, Bonsmann, Susanne, Collins, Deborah J., Rice, Terri L., Prichard, Mark N.
Published in Antiviral research (01.01.2018)
Published in Antiviral research (01.01.2018)
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Vaccinia virus lacking the deoxyuridine triphosphatase gene (F2L) replicates well in vitro and in vivo, but is hypersensitive to the antiviral drug (N)-methanocarbathymidine
Prichard, Mark N, Kern, Earl R, Quenelle, Debra C, Keith, Kathy A, Moyer, Richard W, Turner, Peter C
Published in Virology journal (05.03.2008)
Published in Virology journal (05.03.2008)
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