MACROCYCLES AS FACTOR XIA INHIBITORS
CORTE, James, R, YANG, Wu, ROSSI, Karen, A, QUAN, Mimi, L, DECICCO, Carl, P, PINTO, Donald, J., P, HU, Zilun, WANG, Yufeng, FANG, Tianan, JEON, Yoon, SMALLHEER, Joanne, M
Year of Publication 05.08.2020
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Year of Publication 05.08.2020
Patent
Discovery of 1-[3-(Aminomethyl)phenyl]- N -[3-fluoro-2‘-(methylsulfonyl)- [1,1‘-biphenyl]-4-yl]-3-(trifluoromethyl)-1 H -pyrazole-5-carboxamide (DPC423), a Highly Potent, Selective, and Orally Bioavailable Inhibitor of Blood Coagulation Factor Xa
Pinto, Donald J. P., Orwat, Michael J., Wang, Shuaige, Fevig, John M., Quan, Mimi L., Amparo, Eugene, Cacciola, Joseph, Rossi, Karen A., Alexander, Richard S., Smallwood, Angela M., Luettgen, Joseph M., Liang, Li, Aungst, Bruce J., Wright, Matthew R., Knabb, Robert M., Wong, Pancras C., Wexler, Ruth R., Lam, Patrick Y. S.
Published in Journal of medicinal chemistry (01.02.2001)
Published in Journal of medicinal chemistry (01.02.2001)
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Journal Article
Macrocycles as factor XIa inhibitors
Quan, Mimi L, Rossi, Karen A, Decicco, Carl P, Wang, Yufeng, Pinto, Donald J. P, Fang, Tianan, Smallheer, Joanne M, Corte, James R, Hu, Zilun, Jeon, Yoon, Yang, Wu
Year of Publication 26.11.2019
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Year of Publication 26.11.2019
Patent
Five-membered heterocycles useful as serine protease inhibitors
Quan, Mimi L, Rossi, Karen A, Smallheer, Joanne M, Friends, Todd J, Sun, Zhong, Bisacchi, Gregory S, Corte, James R, Hangeland, Jon J, Cavallaro, Cullen L
Year of Publication 30.10.2018
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Year of Publication 30.10.2018
Patent
LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS
Quan, Mimi L, Lam, Patrick Y.S, Han, Wei, Pinto, Donald J.P, Li, Yun-Long, Qiao, Jennifer X, Koch, Stephanie L, Orwat, Michael J
Year of Publication 30.08.2018
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Year of Publication 30.08.2018
Patent