A highly polarized TH2 bladder response to infection promotes epithelial repair at the expense of preventing new infections
Wu Jianxuan, Hayes, Byron W, Phoenix, Cassandra, Macias Gustavo Sosa, Miao Yuxuan, Choi, Hae Woong, Hughes, Francis M, Todd, Purves J, Lee, Reinhardt R, Abraham, Soman N
Published in Nature immunology (01.06.2020)
Published in Nature immunology (01.06.2020)
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Journal Article
Bladder fibrosis during outlet obstruction is triggered through the NLRP3 inflammasome and the production of IL-1β
Hughes, Jr, Francis M, Sexton, Stephanie J, Jin, Huixia, Govada, Vihasa, Purves, J Todd
Published in American journal of physiology. Renal physiology (01.09.2017)
Published in American journal of physiology. Renal physiology (01.09.2017)
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Journal Article
Specialized pro-resolution mediators in the bladder: Receptor expression and recovery of bladder function from cystitis
Hughes, Francis M, Allkanjari, Armand, Odom, Michael R, Jin, Huixia, Purves, J Todd
Published in Experimental biology and medicine (Maywood, N.J.) (01.04.2022)
Published in Experimental biology and medicine (Maywood, N.J.) (01.04.2022)
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Journal Article
Patient education and extracorporeal membrane oxygenation preferences of patients and providers in COVID care
Borre, Ethan D, Maciejewski, Matthew L, Fink, Arlene, Burnside, Melissa, Purves, J. Todd, Scales, Charles D, Fan, Eddy, Sandhu, Bhawandip, Pignone, Kevin, Palmer, Caroline, Webb, Carrington, Guggenheim, Dana S, Zhang, Yuqi
Published in PloS one (13.08.2024)
Published in PloS one (13.08.2024)
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Journal Article
Why Are Some People with Lower Urinary Tract Symptoms (LUTS) Depressed? New Evidence That Peripheral Inflammation in the Bladder Causes Central Inflammation and Mood Disorders
Hughes, Jr, Francis M, Odom, Michael R, Cervantes, Anissa, Livingston, Austin J, Purves, J Todd
Published in International journal of molecular sciences (01.02.2023)
Published in International journal of molecular sciences (01.02.2023)
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Journal Article
Diabetic bladder dysfunction progresses from an overactive to an underactive phenotype in a type-1 diabetic mouse model (Akita female mouse) and is dependent on NLRP3
Hughes, Francis M., Allkanjari, Armand, Odom, Michael R., Jin, Huixia, Purves, J. Todd
Published in Life sciences (1973) (15.06.2022)
Published in Life sciences (1973) (15.06.2022)
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Journal Article
Male Akita mice develop signs of bladder underactivity independent of NLRP3 as a result of a decrease in neurotransmitter release from efferent neurons
Hughes, Jr, Francis M, Allkanjari, Armand, Odom, Michael R, Mulcrone, Jack E, Jin, Huixia, Purves, J Todd
Published in American journal of physiology. Renal physiology (01.07.2023)
Published in American journal of physiology. Renal physiology (01.07.2023)
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Journal Article
Enzyme-induced hypoxia leads to inflammation in urothelial cells in vitro
Hudson, Britney N., Purves, J. Todd, Hughes, Francis M., Nagatomi, Jiro
Published in International urology and nephrology (01.05.2024)
Published in International urology and nephrology (01.05.2024)
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Journal Article
Evaluation of Poly (Carbonate-Urethane) Urea (PCUU) Scaffolds for Urinary Bladder Tissue Engineering
Sivaraman, Srikanth, Amoroso, Nicholas, Gu, Xinzhu, Purves, J. Todd, Hughes, Francis M., Wagner, William R., Nagatomi, Jiro
Published in Annals of biomedical engineering (01.03.2019)
Published in Annals of biomedical engineering (01.03.2019)
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Journal Article
Elevated hydrostatic pressure stimulates ATP release which mediates activation of the NLRP3 inflammasome via P2X4 in rat urothelial cells
Dunton, Cody L., Purves, J. Todd, Hughes, Francis M., Jin, Huixia, Nagatomi, Jiro
Published in International urology and nephrology (01.09.2018)
Published in International urology and nephrology (01.09.2018)
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Journal Article
Inflammasomes in the urinary tract: a disease-based review
Purves, J Todd, Hughes, Jr, F Monty
Published in American journal of physiology. Renal physiology (01.10.2016)
Published in American journal of physiology. Renal physiology (01.10.2016)
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Journal Article
Specialized proresolution mediators in the bladder: annexin-A1 normalizes inflammation and bladder dysfunction during bladder outlet obstruction
Hughes, Francis M., Harper, Shelby N., Nosé, Brent D., Allkanjari, Armand, Zheng, Michael T., Jin, Huixia, Purves, J. Todd
Published in American journal of physiology. Renal physiology (01.10.2021)
Published in American journal of physiology. Renal physiology (01.10.2021)
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Journal Article
Strict glucose control and elimination of NLRP3‐induced inflammation prevents diabetic bladder dysfunction in the female Akita mouse model
Hughes, Francis M., Harper, Shelby N., Jin, Huixia, Odom, Michael R., Todd Purves, J.
Published in Neurourology and urodynamics (20.07.2024)
Published in Neurourology and urodynamics (20.07.2024)
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Journal Article
The NLRP3 Inflammasome Mediates Inflammation Produced by Bladder Outlet Obstruction
Hughes, Francis M, Hill, Hayden M, Wood, Case M, Edmondson, Andrew T, Dumas, Aliya, Foo, Wen-Chi, Oelsen, James M, Rac, Goran, Purves, J. Todd
Published in The Journal of urology (01.05.2016)
Published in The Journal of urology (01.05.2016)
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Journal Article
Pediatric Neurogenic Bladder and Bowel Dysfunction: Will My Child Ever Be out of Diapers?
Johnston, Ashley W., Wiener, John S., Todd Purves, J.
Published in European urology focus (15.09.2020)
Published in European urology focus (15.09.2020)
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Journal Article
Cyclophosphamide-induced cystitis results in NLRP3-mediated inflammation in the hippocampus and symptoms of depression in rats
Hirshman, Nathan A, Hughes, Jr, Francis M, Jin, Huixia, Harrison, William T, White, Simon W, Doan, Isabelle, Harper, Shelby N, Leidig, Patrick D, Purves, J Todd
Published in American journal of physiology. Renal physiology (01.02.2020)
Published in American journal of physiology. Renal physiology (01.02.2020)
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Journal Article