A highly polarized TH2 bladder response to infection promotes epithelial repair at the expense of preventing new infections
Wu, Jianxuan, Hayes, Byron W., Phoenix, Cassandra, Macias, Gustavo Sosa, Miao, Yuxuan, Choi, Hae Woong, Hughes, Francis M., Todd Purves, J., Lee Reinhardt, R., Abraham, Soman N.
Published in Nature immunology (01.06.2020)
Published in Nature immunology (01.06.2020)
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Journal Article
Bladder fibrosis during outlet obstruction is triggered through the NLRP3 inflammasome and the production of IL-1β
Hughes, Jr, Francis M, Sexton, Stephanie J, Jin, Huixia, Govada, Vihasa, Purves, J Todd
Published in American journal of physiology. Renal physiology (01.09.2017)
Published in American journal of physiology. Renal physiology (01.09.2017)
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Journal Article
Strict glucose control and elimination of NLRP3‐induced inflammation prevents diabetic bladder dysfunction in the female Akita mouse model
Hughes, Francis M., Harper, Shelby N., Jin, Huixia, Odom, Michael R., Purves, J. Todd
Published in Neurourology and urodynamics (01.11.2024)
Published in Neurourology and urodynamics (01.11.2024)
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Journal Article
Diabetic bladder dysfunction progresses from an overactive to an underactive phenotype in a type-1 diabetic mouse model (Akita female mouse) and is dependent on NLRP3
Hughes, Francis M., Allkanjari, Armand, Odom, Michael R., Jin, Huixia, Purves, J. Todd
Published in Life sciences (1973) (15.06.2022)
Published in Life sciences (1973) (15.06.2022)
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Journal Article
Why Are Some People with Lower Urinary Tract Symptoms (LUTS) Depressed? New Evidence That Peripheral Inflammation in the Bladder Causes Central Inflammation and Mood Disorders
Hughes, Jr, Francis M, Odom, Michael R, Cervantes, Anissa, Livingston, Austin J, Purves, J Todd
Published in International journal of molecular sciences (01.02.2023)
Published in International journal of molecular sciences (01.02.2023)
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Journal Article
Patient education and extracorporeal membrane oxygenation preferences of patients and providers in COVID care
Borre, Ethan D, Maciejewski, Matthew L, Fink, Arlene, Burnside, Melissa, Purves, J Todd, Scales, Jr, Charles D, Fan, Eddy, Sandhu, Bhawandip, Pignone, Kevin, Palmer, Caroline, Webb, Carrington, Guggenheim, Dana S, Zhang, Yuqi
Published in PloS one (13.08.2024)
Published in PloS one (13.08.2024)
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Journal Article
Evaluation of Poly (Carbonate-Urethane) Urea (PCUU) Scaffolds for Urinary Bladder Tissue Engineering
Sivaraman, Srikanth, Amoroso, Nicholas, Gu, Xinzhu, Purves, J. Todd, Hughes, Francis M., Wagner, William R., Nagatomi, Jiro
Published in Annals of biomedical engineering (01.03.2019)
Published in Annals of biomedical engineering (01.03.2019)
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Journal Article
Inflammasomes in the urinary tract: a disease-based review
Purves, J Todd, Hughes, Jr, F Monty
Published in American journal of physiology. Renal physiology (01.10.2016)
Published in American journal of physiology. Renal physiology (01.10.2016)
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Journal Article
NLRP3 Promotes Diabetic Bladder Dysfunction and Changes in Symptom-Specific Bladder Innervation
Hughes, Jr, Francis M, Hirshman, Nathan A, Inouye, Brian M, Jin, Huixia, Stanton, Eloise W, Yun, Chloe E, Davis, Leah G, Routh, Jonathan C, Purves, J Todd
Published in Diabetes (New York, N.Y.) (01.02.2019)
Published in Diabetes (New York, N.Y.) (01.02.2019)
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Journal Article
Elevated hydrostatic pressure stimulates ATP release which mediates activation of the NLRP3 inflammasome via P2X4 in rat urothelial cells
Dunton, Cody L., Purves, J. Todd, Hughes, Francis M., Jin, Huixia, Nagatomi, Jiro
Published in International urology and nephrology (01.09.2018)
Published in International urology and nephrology (01.09.2018)
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Journal Article
Pediatric Neurogenic Bladder and Bowel Dysfunction: Will My Child Ever Be out of Diapers?
Johnston, Ashley W., Wiener, John S., Todd Purves, J.
Published in European urology focus (15.09.2020)
Published in European urology focus (15.09.2020)
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Journal Article
A novel urodynamic model for lower urinary tract assessment in awake rats
Schneider, Marc P., Hughes, Francis M., Engmann, Anne K., Purves, J. Todd, Kasper, Hansjörg, Tedaldi, Marco, Spruill, Laura S., Gullo, Miriam, Schwab, Martin E., Kessler, Thomas M.
Published in BJU international (01.04.2015)
Published in BJU international (01.04.2015)
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Journal Article
Inflammasomes are important mediators of cyclophosphamide-induced bladder inflammation
Hughes, Jr, Francis M, Vivar, Nivardo P, Kennis, James G, Pratt-Thomas, Jeffery D, Lowe, Danielle W, Shaner, Brooke E, Nietert, Paul J, Spruill, Laura S, Purves, J Todd
Published in American journal of physiology. Renal physiology (01.02.2014)
Published in American journal of physiology. Renal physiology (01.02.2014)
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Journal Article
Female Type 1 Diabetic Akita Mice Demonstrate Increased Bladder Contractility via FP Receptor Activation due to NLRP3-Mediated Inflammation
Odom, Michael R, Hughes, Jr, Francis M, Pope, NiQuava, Jin, Huixia, Purves, J Todd
Published in Frontiers in bioscience (Landmark. Print) (18.04.2024)
Published in Frontiers in bioscience (Landmark. Print) (18.04.2024)
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Journal Article
Association between race and in-hospital outcomes in children with spina bifida following inpatient urologic surgery
Chandrapal, Jason, Simmons, Kirsten, Purves, J Todd, Wiener, John S, Routh, Jonathan C
Published in Journal of pediatric rehabilitation medicine (01.01.2021)
Published in Journal of pediatric rehabilitation medicine (01.01.2021)
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Journal Article
The potential repertoire of the innate immune system in the bladder: expression of pattern recognition receptors in the rat bladder and a rat urothelial cell line (MYP3 cells)
Hughes, Francis M., Turner, David P., Todd Purves, J.
Published in International urology and nephrology (01.12.2015)
Published in International urology and nephrology (01.12.2015)
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Journal Article