The effects of the anti-hepcidin Spiegelmer NOX-H94 on inflammation-induced anemia in cynomolgus monkeys
Schwoebel, Frank, van Eijk, Lucas T., Zboralski, Dirk, Sell, Simone, Buchner, Klaus, Maasch, Christian, Purschke, Werner G., Humphrey, Martin, Zöllner, Stefan, Eulberg, Dirk, Morich, Frank, Pickkers, Peter, Klussmann, Sven
Published in Blood (21.03.2013)
Published in Blood (21.03.2013)
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Journal Article
SDF-1 inhibition targets the bone marrow niche for cancer therapy
Roccaro, Aldo M, Sacco, Antonio, Purschke, Werner G, Moschetta, Michele, Buchner, Klaus, Maasch, Christian, Zboralski, Dirk, Zöllner, Stefan, Vonhoff, Stefan, Mishima, Yuji, Maiso, Patricia, Reagan, Michaela R, Lonardi, Silvia, Ungari, Marco, Facchetti, Fabio, Eulberg, Dirk, Kruschinski, Anna, Vater, Axel, Rossi, Giuseppe, Klussmann, Sven, Ghobrial, Irene M
Published in Cell reports (Cambridge) (09.10.2014)
Published in Cell reports (Cambridge) (09.10.2014)
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Journal Article
A Novel C5a-neutralizing Mirror-image (l-)Aptamer Prevents Organ Failure and Improves Survival in Experimental Sepsis
Hoehlig, Kai, Maasch, Christian, Shushakova, Nelli, Buchner, Klaus, Huber-Lang, Markus, Purschke, Werner G, Vater, Axel, Klussmann, Sven
Published in Molecular therapy (01.12.2013)
Published in Molecular therapy (01.12.2013)
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Journal Article
Primary Central Nervous System (CNS) Lymphoma B Cell Receptors Recognize CNS Proteins
Montesinos-Rongen, Manuel, Purschke, Frauke G, Brunn, Anna, May, Caroline, Nordhoff, Eckhard, Marcus, Katrin, Deckert, Martina
Published in The Journal of immunology (1950) (01.08.2015)
Published in The Journal of immunology (1950) (01.08.2015)
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Journal Article
Hematopoietic Stem and Progenitor Cell Mobilization in Mice and Humans by a First‐in‐Class Mirror‐Image Oligonucleotide Inhibitor of CXCL12
Vater, A, Sahlmann, J, Kröger, N, Zöllner, S, Lioznov, M, Maasch, C, Buchner, K, Vossmeyer, D, Schwoebel, F, Purschke, W G, Vonhoff, S, Kruschinski, A, Hübel, K, Humphrey, M, Klussmann, S, Fliegert, F
Published in Clinical pharmacology and therapeutics (01.07.2013)
Published in Clinical pharmacology and therapeutics (01.07.2013)
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Journal Article
Identification and characterization of a mirror-image oligonucleotide that binds and neutralizes sphingosine 1-phosphate, a central mediator of angiogenesis
Purschke, Werner G, Hoehlig, Kai, Buchner, Klaus, Zboralski, Dirk, Schwoebel, Frank, Vater, Axel, Klussmann, Sven
Published in Biochemical journal (15.08.2014)
Published in Biochemical journal (15.08.2014)
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Journal Article
Polyetheylenimine-Polyplexes of Spiegelmer NOX-A50 Directed against Intracellular High Mobility Group Protein A1 (HMGA1) Reduce Tumor Growth in Vivo
Maasch, Christian, Vater, Axel, Buchner, Klaus, Purschke, Werner G., Eulberg, Dirk, Vonhoff, Stefan, Klussmann, Sven
Published in The Journal of biological chemistry (17.12.2010)
Published in The Journal of biological chemistry (17.12.2010)
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Journal Article
Sinorhizobium meliloti CheA Complexed with CheS Exhibits Enhanced Binding to CheY1, Resulting in Accelerated CheY1 Dephosphorylation
Dogra, Gaurav, Purschke, Frauke G, Wagner, Verena, Haslbeck, Martin, Kriehuber, Thomas, Hughes, Jonathan G, Van Tassell, Maxwell L, Gilbert, Crystal, Niemeyer, Melanie, Ray, W. Keith, Helm, Richard F, Scharf, Birgit E
Published in Journal of Bacteriology (01.03.2012)
Published in Journal of Bacteriology (01.03.2012)
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Journal Article
A DNA Spiegelmer to staphylococcal enterotoxin B
Purschke, Werner G., Radtke, Falko, Kleinjung, Frank, Klussmann, Sven
Published in Nucleic acids research (15.06.2003)
Published in Nucleic acids research (15.06.2003)
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Journal Article
The phylogenetic position of the Aeolosomatidae and Parergodrilidae, two enigmatic oligochaete-like taxa of the 'Polychaeta', based on molecular data from 18S rDNA sequences
Struck, T., Hessling, R., Purschke, G.
Published in Journal of zoological systematics and evolutionary research (01.09.2002)
Published in Journal of zoological systematics and evolutionary research (01.09.2002)
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Journal Article
An L-RNA-Based Aquaretic Agent That Inhibits Vasopressin in Vivo
Purschke, Werner G., Eulberg, Dirk, Buchner, Klaus, Vonhoff, Stefan, Klussmann, Sven
Published in Proceedings of the National Academy of Sciences - PNAS (28.03.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (28.03.2006)
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Journal Article
Phylogenetic inference regarding Parergodrilidae and Hrabeiella periglandulata (‘Polychaeta’, Annelida) based on 18S rDNA, 28S rDNA and COI sequences
Jördens, J., Struck, T., Purschke, G.
Published in Journal of zoological systematics and evolutionary research (01.11.2004)
Published in Journal of zoological systematics and evolutionary research (01.11.2004)
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Journal Article
A Mixed Mirror-image DNA/RNA Aptamer Inhibits Glucagon and Acutely Improves Glucose Tolerance in Models of Type 1 and Type 2 Diabetes
Vater, Axel, Sell, Simone, Kaczmarek, Przemyslaw, Maasch, Christian, Buchner, Klaus, Pruszynska-Oszmalek, Ewa, Kolodziejski, Pawel, Purschke, Werner G., Nowak, Krzysztof W., Strowski, Mathias Z., Klussmann, Sven
Published in The Journal of biological chemistry (19.07.2013)
Published in The Journal of biological chemistry (19.07.2013)
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Journal Article
A novel CGRP‐neutralizing Spiegelmer attenuates neurogenic plasma protein extravasation
Hoehlig, K, Johnson, K W, Pryazhnikov, E, Maasch, C, Clemens‐Smith, A, Purschke, W G, Vauléon, S, Buchner, K, Jarosch, F, Khiroug, L, Vater, A, Klussmann, S
Published in British journal of pharmacology (01.06.2015)
Published in British journal of pharmacology (01.06.2015)
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