Causal relationships between obesity and the leading causes of death in women and men
Censin, Jenny C, Peters, Sanne A E, Bovijn, Jonas, Ferreira, Teresa, Pulit, Sara L, Mägi, Reedik, Mahajan, Anubha, Holmes, Michael V, Lindgren, Cecilia M
Published in PLoS genetics (24.10.2019)
Published in PLoS genetics (24.10.2019)
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Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry
Pulit, Sara L, Stoneman, Charli, Morris, Andrew P, Wood, Andrew R, Glastonbury, Craig A, Tyrrell, Jessica, Yengo, Loïc, Ferreira, Teresa, Marouli, Eirini, Ji, Yingjie, Yang, Jian, Jones, Samuel, Beaumont, Robin, Croteau-Chonka, Damien C, Winkler, Thomas W, Hattersley, Andrew T, Loos, Ruth J F, Hirschhorn, Joel N, Visscher, Peter M, Frayling, Timothy M, Yaghootkar, Hanieh, Lindgren, Cecilia M
Published in Human molecular genetics (01.01.2019)
Published in Human molecular genetics (01.01.2019)
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Fine mapping in the MHC region accounts for 18% additional genetic risk for celiac disease
Gutierrez-Achury, Javier, Zhernakova, Alexandra, Pulit, Sara L, Trynka, Gosia, Hunt, Karen A, Romanos, Jihane, Raychaudhuri, Soumya, van Heel, David A, Wijmenga, Cisca, de Bakker, Paul I W
Published in Nature genetics (01.06.2015)
Published in Nature genetics (01.06.2015)
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Evaluating the cardiovascular safety of sclerostin inhibition using evidence from meta-analysis of clinical trials and human genetics
Bovijn, Jonas, Krebs, Kristi, Chen, Chia-Yen, Boxall, Ruth, Censin, Jenny C, Ferreira, Teresa, Pulit, Sara L, Glastonbury, Craig A, Laber, Samantha, Millwood, Iona Y, Lin, Kuang, Li, Liming, Chen, Zhengming, Milani, Lili, Smith, George Davey, Walters, Robin G, Mägi, Reedik, Neale, Benjamin M, Lindgren, Cecilia M, Holmes, Michael V
Published in Science translational medicine (24.06.2020)
Published in Science translational medicine (24.06.2020)
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Machine Learning based histology phenotyping to investigate the epidemiologic and genetic basis of adipocyte morphology and cardiometabolic traits
Glastonbury, Craig A, Pulit, Sara L, Honecker, Julius, Censin, Jenny C, Laber, Samantha, Yaghootkar, Hanieh, Rahmioglu, Nilufer, Pastel, Emilie, Kos, Katerina, Pitt, Andrew, Hudson, Michelle, Nellåker, Christoffer, Beer, Nicola L, Hauner, Hans, Becker, Christian M, Zondervan, Krina T, Frayling, Timothy M, Claussnitzer, Melina, Lindgren, Cecilia M
Published in PLoS computational biology (01.08.2020)
Published in PLoS computational biology (01.08.2020)
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GWAS Identifies Risk Locus for Erectile Dysfunction and Implicates Hypothalamic Neurobiology and Diabetes in Etiology
Bovijn, Jonas, Jackson, Leigh, Censin, Jenny, Chen, Chia-Yen, Laisk, Triin, Laber, Samantha, Ferreira, Teresa, Pulit, Sara L., Glastonbury, Craig A., Smoller, Jordan W., Harrison, Jamie W., Ruth, Katherine S., Beaumont, Robin N., Jones, Samuel E., Tyrrell, Jessica, Wood, Andrew R., Weedon, Michael N., Mägi, Reedik, Neale, Benjamin, Lindgren, Cecilia M., Murray, Anna, Holmes, Michael V.
Published in American journal of human genetics (03.01.2019)
Published in American journal of human genetics (03.01.2019)
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Journal Article
Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1
Cortes, Adrian, Pulit, Sara L., Leo, Paul J., Pointon, Jenny J., Robinson, Philip C., Weisman, Michael H., Ward, Michael, Gensler, Lianne S., Zhou, Xiaodong, Garchon, Henri-Jean, Chiocchia, Gilles, Nossent, Johannes, Lie, Benedicte A., Førre, Øystein, Tuomilehto, Jaakko, Laiho, Kari, Bradbury, Linda A., Elewaut, Dirk, Burgos-Vargas, Ruben, Stebbings, Simon, Appleton, Louise, Farrah, Claire, Lau, Jonathan, Haroon, Nigil, Mulero, Juan, Blanco, Francisco J., Gonzalez-Gay, Miguel A., Lopez-Larrea, C, Bowness, Paul, Gaffney, Karl, Gaston, Hill, Gladman, Dafna D., Rahman, Proton, Maksymowych, Walter P., Crusius, J. Bart A., van der Horst-Bruinsma, Irene E., Valle-Oñate, Raphael, Romero-Sánchez, Consuelo, Hansen, Inger Myrnes, Pimentel-Santos, Fernando M., Inman, Robert D., Martin, Javier, Breban, Maxime, Wordsworth, Bryan Paul, Reveille, John D., Evans, David M., de Bakker, Paul I.W., Brown, Matthew A.
Published in Nature communications (21.05.2015)
Published in Nature communications (21.05.2015)
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An Enhancer Polymorphism at the Cardiomyocyte Intercalated Disc Protein NOS1AP Locus Is a Major Regulator of the QT Interval
Kapoor, Ashish, Sekar, Rajesh B., Hansen, Nancy F., Fox-Talbot, Karen, Morley, Michael, Pihur, Vasyl, Chatterjee, Sumantra, Brandimarto, Jeffrey, Moravec, Christine S., Pulit, Sara L., Pfeufer, Arne, Mullikin, Jim, Ross, Mark, Green, Eric D., Bentley, David, Newton-Cheh, Christopher, Boerwinkle, Eric, Tomaselli, Gordon F., Cappola, Thomas P., Arking, Dan E., Halushka, Marc K., Chakravarti, Aravinda
Published in American journal of human genetics (05.06.2014)
Published in American journal of human genetics (05.06.2014)
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Journal Article
Project MinE: study design and pilot analyses of a large-scale whole-genome sequencing study in amyotrophic lateral sclerosis
Wouter Van Rheenen, Pulit, Sara L, Dekker, Annelot M, Ahmad Al Khleifat, Brands, William J, Iacoangeli, Alfredo, Kenna, Kevin P, Kavak, Ersen, Kooyman, Maarten, McLaughlin, Russell L, Middelkoop, Bas, Moisse, Matthieu, Schellevis, Raymond D, Shatunov, Aleksey, Sproviero, William, Tazelaar, Gijs H P, Rick A A Van der Spek, Perry T C Van Doormaal, Van Eijk, Kristel R, Joke Van Vugt, Basak, A Nazli, Blair, Ian P, Glass, Jonathan D, Hardiman, Orla, Hide, Winston, Landers, John E, Mora, Jesus S, Morrison, Karen E, Newhouse, Stephen, Robberecht, Wim, Shaw, Christopher E, Shaw, Pamela J, Philip Van Damme, Van Es, Michael A, Wray, Naomi R, Al-Chalabi, Ammar, Leonard H Van den Berg, Veldink, Jan H
Published in European journal of human genetics : EJHG (01.10.2018)
Published in European journal of human genetics : EJHG (01.10.2018)
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Genic constraint against nonsynonymous variation across the mouse genome
Powell, George, Simon, Michelle M, Pulit, Sara, Mallon, Ann-Marie, Lindgren, Cecilia M
Published in BMC genomics (22.09.2023)
Published in BMC genomics (22.09.2023)
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Sensitive Monogenic Noninvasive Prenatal Diagnosis by Targeted Haplotyping
Vermeulen, Carlo, Geeven, Geert, de Wit, Elzo, Verstegen, Marjon J.A.M., Jansen, Rumo P.M., van Kranenburg, Melissa, de Bruijn, Ewart, Pulit, Sara L., Kruisselbrink, Evelien, Shahsavari, Zahra, Omrani, Davood, Zeinali, Fatemeh, Najmabadi, Hossein, Katsila, Theodora, Vrettou, Christina, Patrinos, George P., Traeger-Synodinos, Joanne, Splinter, Erik, Beekman, Jeffrey M., Kheradmand Kia, Sima, te Meerman, Gerard J., Ploos van Amstel, Hans Kristian, de Laat, Wouter
Published in American journal of human genetics (07.09.2017)
Published in American journal of human genetics (07.09.2017)
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Colocalization of Gene Expression and DNA Methylation with Genetic Risk Variants Supports Functional Roles of MUC5B and DSP in Idiopathic Pulmonary Fibrosis
Borie, Raphael, Cardwell, Jonathan, Konigsberg, Iain R, Moore, Camille M, Zhang, Weiming, Sasse, Sarah K, Gally, Fabienne, Dobrinskikh, Evgenia, Walts, Avram, Powers, Julie, Brancato, Janna, Rojas, Mauricio, Wolters, Paul J, Brown, Kevin K, Blackwell, Timothy S, Nakanishi, Tomoko, Richards, J Brent, Gerber, Anthony N, Fingerlin, Tasha E, Sachs, Norman, Pulit, Sara L, Zappala, Zachary, Schwartz, David A, Yang, Ivana V
Published in American journal of respiratory and critical care medicine (15.11.2022)
Published in American journal of respiratory and critical care medicine (15.11.2022)
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Deleterious alleles in the human genome are on average younger than neutral alleles of the same frequency
Kiezun, Adam, Pulit, Sara L, Francioli, Laurent C, van Dijk, Freerk, Swertz, Morris, Boomsma, Dorret I, van Duijn, Cornelia M, Slagboom, P Eline, van Ommen, G J B, Wijmenga, Cisca, de Bakker, Paul I W, Sunyaev, Shamil R
Published in PLoS genetics (01.02.2013)
Published in PLoS genetics (01.02.2013)
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The project MinE databrowser: bringing large-scale whole-genome sequencing in ALS to researchers and the public
van der Spek, Rick A.A., van Rheenen, Wouter, Pulit, Sara L., Kenna, Kevin P., van den Berg, Leonard H., Veldink, Jan H.
Published in Amyotrophic lateral sclerosis and frontotemporal degeneration (03.07.2019)
Published in Amyotrophic lateral sclerosis and frontotemporal degeneration (03.07.2019)
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A genome-wide association study identifies a functional ERAP2 haplotype associated with birdshot chorioretinopathy
Kuiper, Jonas J W, Van Setten, Jessica, Ripke, Stephan, Van 'T Slot, Ruben, Mulder, Flip, Missotten, Tom, Baarsma, G Seerp, Francioli, Laurent C, Pulit, Sara L, De Kovel, Carolien G F, Ten Dam-Van Loon, Ninette, Den Hollander, Anneke I, Huis in het Veld, Paulien, Hoyng, Carel B, Cordero-Coma, Miguel, Martín, Javier, Llorenç, Victor, Arya, Bharti, Thomas, Dhanes, Bakker, Steven C, Ophoff, Roel A, Rothova, Aniki, De Bakker, Paul I W, Mutis, Tuna, Koeleman, Bobby P C
Published in Human molecular genetics (15.11.2014)
Published in Human molecular genetics (15.11.2014)
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Comprehensive pathway analyses of schizophrenia risk loci point to dysfunctional postsynaptic signaling
Schijven, Dick, Kofink, Daniel, Tragante, Vinicius, Verkerke, Marloes, Pulit, Sara L., Kahn, René S., Veldink, Jan H., Vinkers, Christiaan H., Boks, Marco P., Luykx, Jurjen J.
Published in Schizophrenia research (01.09.2018)
Published in Schizophrenia research (01.09.2018)
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