A conserved transcriptional signature of delayed aging and reduced disease vulnerability is partially mediated by SIRT3
Barger, Jamie L, Anderson, Rozalyn M, Newton, Michael A, da Silva, Cristina, Vann, James A, Pugh, Thomas D, Someya, Shinichi, Prolla, Tomas A, Weindruch, Richard
Published in PloS one (01.04.2015)
Published in PloS one (01.04.2015)
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A shift in energy metabolism anticipates the onset of sarcopenia in rhesus monkeys
Pugh, Thomas D., Conklin, Matthew W., Evans, Trent D., Polewski, Michael A., Barbian, Hannah J., Pass, Rachelle, Anderson, Bradley D., Colman, Ricki J., Eliceiri, Kevin W., Keely, Patricia J., Weindruch, Richard, Beasley, T. Mark, Anderson, Rozalyn M.
Published in Aging cell (01.08.2013)
Published in Aging cell (01.08.2013)
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Identification of tissue‐specific transcriptional markers of caloric restriction in the mouse and their use to evaluate caloric restriction mimetics
Barger, Jamie L., Vann, James M., Cray, Nicole L., Pugh, Thomas D., Mastaloudis, Angela, Hester, Shelly N., Wood, Steven M., Newton, Michael A., Weindruch, Richard, Prolla, Tomas A.
Published in Aging cell (01.08.2017)
Published in Aging cell (01.08.2017)
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Regional metabolic heterogeneity of the hippocampus is nonuniformly impacted by age and caloric restriction
Martin, Stephen A., DeMuth, Tyler M., Miller, Karl N., Pugh, Thomas D., Polewski, Michael A., Colman, Ricki J., Eliceiri, Kevin W., Beasley, Timothy Mark, Johnson, Sterling C., Anderson, Rozalyn M.
Published in Aging cell (01.02.2016)
Published in Aging cell (01.02.2016)
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The role of mtDNA mutations in the pathogenesis of age-related hearing loss in mice carrying a mutator DNA polymerase γ
Someya, Shinichi, Yamasoba, Tatsuya, Kujoth, Gregory C, Pugh, Thomas D, Weindruch, Richard, Tanokura, Masaru, Prolla, Tomas A
Published in Neurobiology of aging (01.07.2008)
Published in Neurobiology of aging (01.07.2008)
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Adipose tissue energy metabolism: altered gene expression profile of mice subjected to long-term caloric restriction
Higami, Yoshikazu, Pugh, Thomas D, Page, Grier P, Allison, David B, Prolla, Tomas A, Weindruch, Richard
Published in The FASEB journal (01.02.2004)
Published in The FASEB journal (01.02.2004)
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The impact of alpha-lipoic acid, coenzyme Q10 and caloric restriction on life span and gene expression patterns in mice
Lee, Cheol-Koo, Pugh, Thomas D, Klopp, Roger G, Edwards, Jode, Allison, David B, Weindruch, Richard, Prolla, Tomas A
Published in Free radical biology & medicine (15.04.2004)
Published in Free radical biology & medicine (15.04.2004)
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Calorie restriction attenuates astrogliosis but not amyloid plaque load in aged rhesus macaques: A preliminary quantitative imaging study
Sridharan, Aadhavi, Pehar, Mariana, Salamat, M. Shahriar, Pugh, Thomas D, Bendlin, Barbara B, Willette, Auriel A, Anderson, Rozalyn M, Kemnitz, Joseph W, Colman, Ricki J, Weindruch, Richard H, Puglielli, Luigi, Johnson, Sterling C
Published in Brain research (01.05.2013)
Published in Brain research (01.05.2013)
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Gene expression profiling reveals differential effects of sodium selenite, selenomethionine, and yeast-derived selenium in the mouse
Barger, Jamie L, Kayo, Tsuyoshi, Pugh, Thomas D, Vann, James A, Power, Ronan, Dawson, Karl, Weindruch, Richard, Prolla, Tomas A
Published in Genes & nutrition (01.04.2012)
Published in Genes & nutrition (01.04.2012)
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Blood pressure, artery size, and artery compliance parallel bone size and strength in mice with differing ece1 expression
Wang, Zhijie, Kristianto, Jasmin, Yen Ooi, Chen, Johnson, Michael G, Litscher, Suzanne J, Pugh, Thomas D, Sandhu, Gurpreet, Chesler, Naomi C, Blank, Robert D
Published in Journal of biomechanical engineering (01.06.2013)
Published in Journal of biomechanical engineering (01.06.2013)
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Safety of interleukin-12 gene therapy against cancer: a murine biodistribution and toxicity study
Imboden, Michael, Shi, Fushun, Pugh, Thomas D, Freud, Aharon G, Thom, Nathaniel J, Hank, Jacquelin A, Hao, Zhengling, Staelin, Stephen T, Sondel, Paul M, Mahvi, David M
Published in Human gene therapy (20.07.2003)
Published in Human gene therapy (20.07.2003)
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Influence of fat intake and caloric restriction on bone in aging male rats
Sanderson, J P, Binkley, N, Roecker, E B, Champ, J E, Pugh, T D, Aspnes, L, Weindruch, R
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01.01.1997)
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01.01.1997)
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Dietary restriction from middle age attenuates age-associated lymphoma development and interleukin 6 dysregulation in C57BL/6 mice
VOLK, M. J, PUGH, T. D, MOONJU KIM, FRITH, C. H, DAYNES, R. A, ERSHLER, W. B, WEINDRUCH, R
Published in Cancer research (Chicago, Ill.) (01.06.1994)
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Published in Cancer research (Chicago, Ill.) (01.06.1994)
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Prostatic localization of spontaneous early invasive carcinoma in Lobund-Wistar rats
PUGH, T. D, CHANG, C, UEMURA, H, WEINDRUCH, R
Published in Cancer research (Chicago, Ill.) (15.11.1994)
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Published in Cancer research (Chicago, Ill.) (15.11.1994)
Journal Article
Reliable stereological method for estimating the number of microscopic hepatocellular foci from their transections
Pugh, T D, King, J H, Koen, H, Nychka, D, Chover, J, Wahba, G, He, Y H, Goldfarb, S
Published in Cancer research (Chicago, Ill.) (01.03.1983)
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Published in Cancer research (Chicago, Ill.) (01.03.1983)
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