The VHL tumor suppressor inhibits expression of the IGF1R and its loss induces IGF1R upregulation in human clear cell renal carcinoma
YUEN, J. S. P, COCKMAN, M. E, SULLIVAN, M, PROTHEROE, A, TURNER, G. D. H, ROBERTS, I. S, PUGH, C. W, WERNER, H, MACAULAY, V. M
Published in Oncogene (04.10.2007)
Published in Oncogene (04.10.2007)
Get full text
Journal Article
Hypoxia-Inducible Factor-1 Modulates Gene Expression in Solid Tumors and Influences Both Angiogenesis and Tumor Growth
Maxwell, P. H., Dachs, G. U., Gleadle, J. M., Nicholls, L. G., Harris, A. L., Stratford, I. J., Hankinson, O., Pugh, C. W., Ratcliffe, P. J.
Published in Proceedings of the National Academy of Sciences - PNAS (22.07.1997)
Published in Proceedings of the National Academy of Sciences - PNAS (22.07.1997)
Get full text
Journal Article
Use of novel monoclonal antibodies to determine the expression and distribution of the hypoxia regulatory factors PHD-1, PHD-2, PHD-3 and FIH in normal and neoplastic human tissues
Soilleux, E J, Turley, H, Tian, Y M, Pugh, C W, Gatter, K C, Harris, A L
Published in Histopathology (01.12.2005)
Published in Histopathology (01.12.2005)
Get full text
Journal Article
The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages
Talks, Katherine L., Turley, Helen, Gatter, Kevin C., Maxwell, Patrick H., Pugh, Christopher W., Ratcliffe, Peter J., Harris, Adrian L.
Published in The American journal of pathology (01.08.2000)
Published in The American journal of pathology (01.08.2000)
Get full text
Journal Article
Hypoxia Inducible Factor-α Binding and Ubiquitylation by the von Hippel-Lindau Tumor Suppressor Protein
Cockman, Matthew E., Masson, Norma, Mole, David R., Jaakkola, Panu, Chang, Gin-Wen, Clifford, Steven C., Maher, Eamonn R., Pugh, Christopher W., Ratcliffe, Peter J., Maxwell, Patrick H.
Published in The Journal of biological chemistry (18.08.2000)
Published in The Journal of biological chemistry (18.08.2000)
Get full text
Journal Article
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
Ratcliffe, Peter J, Maxwell, Patrick H, Wiesener, Michael S, Chang, Gin-Wen, Clifford, Steven C, Vaux, Emma C, Cockman, Matthew E, Wykoff, Charles C, Pugh, Christopher W, Maher, Eamonn R
Published in Nature (London) (20.05.1999)
Published in Nature (London) (20.05.1999)
Get full text
Journal Article
Hyper-CVAD and high-dose methotrexate/cytarabine followed by stem-cell transplantation: an active regimen for aggressive mantle-cell lymphoma
Khouri, I F, Romaguera, J, Kantarjian, H, Palmer, J L, Pugh, W C, Korbling, M, Hagemeister, F, Samuels, B, Rodriguez, A, Giralt, S, Younes, A, Przepiorka, D, Claxton, D, Cabanillas, F, Champlin, R
Published in Journal of clinical oncology (01.12.1998)
Published in Journal of clinical oncology (01.12.1998)
Get more information
Journal Article
Oxygen-Regulated Control Elements in the Phosphoglycerate Kinase 1 and Lactate Dehydrogenase A Genes: Similarities with the Erythropoietin 3' Enhancer
Firth, J. D., Ebert, B. L., Pugh, C. W., Ratcliffe, P. J.
Published in Proceedings of the National Academy of Sciences - PNAS (05.07.1994)
Published in Proceedings of the National Academy of Sciences - PNAS (05.07.1994)
Get full text
Journal Article
Photoplethysmographic derivation of respiratory rate: a review of relevant physiology
Meredith, D. J., Clifton, D., Charlton, P., Brooks, J., Pugh, C. W., Tarassenko, L.
Published in Journal of medical engineering & technology (01.03.2012)
Published in Journal of medical engineering & technology (01.03.2012)
Get full text
Journal Article
The pVHL-hIF-1 system. A key mediator of oxygen homeostasis
Maxwell, P H, Pugh, C W, Ratcliffe, P J
Published in Advances in experimental medicine and biology (2001)
Published in Advances in experimental medicine and biology (2001)
Get more information
Journal Article