A novel strategy to generate immunocytokines with activity-on-demand using small molecule inhibitors
Rotta, Giulia, Gilardoni, Ettore, Ravazza, Domenico, Mock, Jacqueline, Seehusen, Frauke, Elsayed, Abdullah, Puca, Emanuele, De Luca, Roberto, Pellegrino, Christian, Look, Thomas, Weiss, Tobias, Manz, Markus G, Halin, Cornelia, Neri, Dario, Dakhel Plaza, Sheila
Published in EMBO molecular medicine (15.04.2024)
Published in EMBO molecular medicine (15.04.2024)
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Journal Article
Middle Cerebral Artery Dissection: A Report of Two Cases With Treatments and Outcomes
Papiri, Giulio, Bruni, Stefano, Puca, Emanuele, Sanguigni, Sandro, Marcucci, Matteo
Published in Curēus (Palo Alto, CA) (29.05.2023)
Published in Curēus (Palo Alto, CA) (29.05.2023)
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Journal Article
A Case of Anti-Leucine-Rich Glioma-Inactivated Protein 1 (Anti-LGI1) Encephalitis With an Unusual Frontomesial Motor Cortex T2 MRI Hyperintensity
Papiri, Giulio, Puca, Emanuele, Marcucci, Matteo, Paci, Cristina, Cagnetti, Claudia
Published in Curēus (Palo Alto, CA) (19.10.2022)
Published in Curēus (Palo Alto, CA) (19.10.2022)
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Journal Article
Generation and in vivo characterization of a novel high-affinity human antibody targeting carcinoembryonic antigen
Plüss, Louis, Peissert, Frederik, Elsayed, Abdullah, Rotta, Giulia, Römer, Jonas, Dakhel Plaza, Sheila, Villa, Alessandra, Puca, Emanuele, De Luca, Roberto, Oxenius, Annette, Neri, Dario
Published in mAbs (2023)
Published in mAbs (2023)
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Journal Article
Generation of a novel fully human non-superagonistic anti-CD28 antibody with efficient and safe T-cell co-stimulation properties
Elsayed, Abdullah, Pellegrino, Christian, Plüss, Louis, Peissert, Frederik, Benz, Ramon, Ulrich, Franziska, Thorhallsdottir, Gudrun, Plaza, Sheila Dakhel, Villa, Alessandra, Mock, Jacqueline, Puca, Emanuele, De Luca, Roberto, Manz, Markus G, Halin, Cornelia, Neri, Dario
Published in mAbs (2023)
Published in mAbs (2023)
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Journal Article
An IL-7 fusion protein targeting EDA fibronectin upregulates TCF1 on CD8+ T-cells, preferentially accumulates to neoplastic lesions, and boosts PD-1 blockade
Di Nitto, Cesare, Ravazza, Domenico, Gilardoni, Ettore, Look, Thomas, Sun, Miaomiao, Prodi, Eleonora, Moisoiu, Vlad, Pellegrino, Christian, Manz, Markus G., Puca, Emanuele, Weller, Michael, Weiss, Tobias, Neri, Dario, De Luca, Roberto
Published in Journal for immunotherapy of cancer (13.08.2024)
Published in Journal for immunotherapy of cancer (13.08.2024)
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Journal Article
An Engineered IFNγ-Antibody Fusion Protein with Improved Tumor-Homing Properties
Di Nitto, Cesare, Gilardoni, Ettore, Mock, Jacqueline, Nadal, Lisa, Weiss, Tobias, Weller, Michael, Seehusen, Frauke, Libbra, Chiara, Puca, Emanuele, Neri, Dario, De Luca, Roberto
Published in Pharmaceutics (22.01.2023)
Published in Pharmaceutics (22.01.2023)
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Journal Article
Percheron Artery Stroke and Reperfusive therapies: A systematic review and meta-analysis
Papiri, Giulio, Puca, Emanuele, Marcucci, Matteo, Paci, Cristina, Petritola, Donatella, Bifolchetti, Stefania, Sanguigni, Sandro, Di Marzio, Fabio, Cacchiò, Gabriella, D'Andreamatteo, Giordano, Cagnetti, Claudia
Published in Brain disorders (01.12.2024)
Published in Brain disorders (01.12.2024)
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Journal Article
An Antibody Targeting Fibroblast Activation Protein Simultaneously Fused to Interleukin-2 and Tumor Necrosis Factor Selectively Localizes to Neoplastic Lesions
Prodi, Eleonora, Comacchio, Claudia, Gilardoni, Ettore, Di Nitto, Cesare, Puca, Emanuele, Neri, Dario, De Luca, Roberto
Published in Antibodies (Basel) (14.04.2023)
Published in Antibodies (Basel) (14.04.2023)
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Journal Article
Generation and in vivo validation of an IL-12 fusion protein based on a novel anti-human FAP monoclonal antibody
Nadal, Lisa, Peissert, Frederik, Elsayed, Abdullah, Weiss, Tobias, Look, Thomas, Weller, Michael, Piro, Geny, Carbone, Carmine, Tortora, Giampaolo, Matasci, Mattia, Favalli, Nicholas, Corbellari, Riccardo, Di Nitto, Cesare, Prodi, Eleonora, Libbra, Chiara, Galeazzi, Simone, Carotenuto, Claudiopietro, Halin, Cornelia, Puca, Emanuele, Neri, Dario, De Luca, Roberto
Published in Journal for immunotherapy of cancer (01.09.2022)
Published in Journal for immunotherapy of cancer (01.09.2022)
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Journal Article
Feasibility and Clinical Utility of Transesophageal Echocardiography in the Acute Phase of Cerebral Ischemia
De Castro, Stefano, MD, Papetti, Federica, MD, Di Angelantonio, Emanuele, MD, MSc, Razmovska, Biljana, MD, Truscelli, Giovanni, MD, Tuderti, Ursula, MD, Puca, Emanuele, MD, Correnti, Agata, MD, Fiorelli, Marco, MD, Prencipe, Massimiliano, MD, Toni, Danilo, MD
Published in The American journal of cardiology (01.11.2010)
Published in The American journal of cardiology (01.11.2010)
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Journal Article
An emergency clinical pathway for stroke patients--results of a cluster randomised trial (isrctn41456865)
De Luca, Assunta, Toni, Danilo, Lauria, Laura, Sacchetti, Maria Luisa, Giorgi Rossi, Paolo, Ferri, Marica, Puca, Emanuele, Prencipe, Massimiliano, Guasticchi, Gabriella
Published in BMC health services research (21.01.2009)
Published in BMC health services research (21.01.2009)
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Journal Article
Immunocytokines are a promising immunotherapeutic approach against glioblastoma
Weiss, Tobias, Puca, Emanuele, Silginer, Manuela, Hemmerle, Teresa, Pazahr, Shila, Bink, Andrea, Weller, Michael, Neri, Dario, Roth, Patrick
Published in Science translational medicine (07.10.2020)
Published in Science translational medicine (07.10.2020)
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Journal Article
Cytokine Biopharmaceuticals with “Activity-on-Demand” for Cancer Therapy
Rotta, Giulia, Puca, Emanuele, Cazzamalli, Samuele, Neri, Dario, Dakhel Plaza, Sheila
Published in Bioconjugate chemistry (21.08.2024)
Published in Bioconjugate chemistry (21.08.2024)
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Journal Article
CTIM-22. PHASE I STUDY RESULTS OF THE ANTIBODY-CYTOKINE FUSION PROTEIN L19TNF IN COMBINATION WITH LOMUSTINE FOR PATIENTS WITH RECURRENT GLIOBLASTOMA REVEAL PROMISING SAFETY AND DURABLE TUMOR RESPONSES
Weiss, Tobias, Puca, Emanuele, Covelli, Alfredo, Gramatzki, Dorothee, Roth, Patrick, Neri, Dario, Hemmerle, Teresa, Weller, Michael
Published in Neuro-oncology (Charlottesville, Va.) (10.11.2023)
Published in Neuro-oncology (Charlottesville, Va.) (10.11.2023)
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Journal Article
The antibody‐based delivery of interleukin‐12 to solid tumors boosts NK and CD8+ T cell activity and synergizes with immune checkpoint inhibitors
Puca, Emanuele, Probst, Philipp, Stringhini, Marco, Murer, Patrizia, Pellegrini, Giovanni, Cazzamalli, Samuele, Hutmacher, Cornelia, Gouyou, Baptiste, Wulhfard, Sarah, Matasci, Mattia, Villa, Alessandra, Neri, Dario
Published in International journal of cancer (01.05.2020)
Published in International journal of cancer (01.05.2020)
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Journal Article
Immunotherapy with Immunocytokines and PD-1 Blockade Enhances the Anticancer Activity of Small Molecule-Drug Conjugates Targeting Carbonic Anhydrase IX
Millul, Jacopo, Krudewig, Christiane, Zana, Aureliano, Dakhel Plaza, Sheila, Puca, Emanuele, Villa, Alessandra, Neri, Dario, Cazzamalli, Samuele
Published in Molecular cancer therapeutics (01.03.2021)
Published in Molecular cancer therapeutics (01.03.2021)
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Journal Article
CTIM-22. THE COMBINATION OF LOMUSTINE AND THE IMMUNOCYTOKINE L19TNF IS A PROMISING TREATMENT FOR RECURRENT GLIOBLASTOMA
Look, Thomas, Puca, Emanuele, Stucchi, Riccardo, De Luca, Roberto, Roth, Patrick, Neri, Dario, Weller, Michael, Hemmerle, Teresa, Weiss, Tobias
Published in Neuro-oncology (Charlottesville, Va.) (14.11.2022)
Published in Neuro-oncology (Charlottesville, Va.) (14.11.2022)
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Journal Article
Intratumoral administration of daromun in non-melanoma skin cancer: Preliminary results from a phase 2 non-randomized controlled trial
Flatz, Lukas, Wagner, Nikolaus B, Denisjuk, Natalja, Do, Peter, Nadal, Lisa, Puca, Emanuele, Elia, Giuliano, Covelli, Alfredo, Neri, Dario, Cozzio, Antonio
Published in Journal of the European Academy of Dermatology and Venereology (22.06.2024)
Published in Journal of the European Academy of Dermatology and Venereology (22.06.2024)
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Journal Article
Intravenous thrombolysis in CADASIL: report of two cases and a systematic review
Pescini, Francesca, Torricelli, Sara, Squitieri, Martina, Giacomucci, Giulia, Poggesi, Anna, Puca, Emanuele, Bianchi, Silvia, Ragno, Michele, Pantoni, Leonardo
Published in Neurological sciences (01.02.2023)
Published in Neurological sciences (01.02.2023)
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