Vitamin A-Retinoic Acid Signaling Regulates Hematopoietic Stem Cell Dormancy
Cabezas-Wallscheid, Nina, Buettner, Florian, Sommerkamp, Pia, Klimmeck, Daniel, Ladel, Luisa, Thalheimer, Frederic B., Pastor-Flores, Daniel, Roma, Leticia P., Renders, Simon, Zeisberger, Petra, Przybylla, Adriana, Schönberger, Katharina, Scognamiglio, Roberta, Altamura, Sandro, Florian, Carolina M., Fawaz, Malak, Vonficht, Dominik, Tesio, Melania, Collier, Paul, Pavlinic, Dinko, Geiger, Hartmut, Schroeder, Timm, Benes, Vladimir, Dick, Tobias P., Rieger, Michael A., Stegle, Oliver, Trumpp, Andreas
Published in Cell (18.05.2017)
Published in Cell (18.05.2017)
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Journal Article
Niche derived netrin-1 regulates hematopoietic stem cell dormancy via its receptor neogenin-1
Renders, Simon, Svendsen, Arthur Flohr, Panten, Jasper, Rama, Nicolas, Maryanovich, Maria, Sommerkamp, Pia, Ladel, Luisa, Redavid, Anna Rita, Gibert, Benjamin, Lazare, Seka, Ducarouge, Benjamin, Schönberger, Katharina, Narr, Andreas, Tourbez, Manon, Dethmers-Ausema, Bertien, Zwart, Erik, Hotz-Wagenblatt, Agnes, Zhang, Dachuan, Korn, Claudia, Zeisberger, Petra, Przybylla, Adriana, Sohn, Markus, Mendez-Ferrer, Simon, Heikenwälder, Mathias, Brune, Maik, Klimmeck, Daniel, Bystrykh, Leonid, Frenette, Paul S, Mehlen, Patrick, de Haan, Gerald, Cabezas-Wallscheid, Nina, Trumpp, Andreas
Published in Nature communications (27.01.2021)
Published in Nature communications (27.01.2021)
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CRISPR-Cas9 mediated generation of a conditional poly(A) binding protein nuclear 1 (Pabpn1) mouse model reveals an essential role for hematopoietic stem cells
Sommerkamp, Pia, Sommerkamp, Alexander C, Zeisberger, Petra, Eiben, Paula Leonie, Narr, Andreas, Korkmaz, Aylin, Przybylla, Adriana, Sohn, Markus, van der Hoeven, Franciscus, Schönig, Kai, Trumpp, Andreas
Published in Scientific reports (03.05.2022)
Published in Scientific reports (03.05.2022)
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LRP8‐mediated selenocysteine uptake is a targetable vulnerability in MYCN‐amplified neuroblastoma
Alborzinia, Hamed, Chen, Zhiyi, Yildiz, Umut, Freitas, Florencio Porto, Vogel, Felix C E, Varga, Julianna Patricia, Batani, Jasmin, Bartenhagen, Christoph, Schmitz, Werner, Büchel, Gabriele, Michalke, Bernhard, Zheng, Jashuo, Meierjohann, Svenja, Girardi, Enrico, Espinet, Elisa, Flórez, Andrés F, Santos, Ancely Ferreira, Aroua, Nesrine, Cheytan, Tasneem, Haenlin, Julie, Schlicker, Lisa, Xavier da Silva, Thamara N, Przybylla, Adriana, Zeisberger, Petra, Superti‐Furga, Giulio, Eilers, Martin, Conrad, Marcus, Fabiano, Marietta, Schweizer, Ulrich, Fischer, Matthias, Schulze, Almut, Trumpp, Andreas, Friedmann Angeli, José Pedro
Published in EMBO molecular medicine (07.08.2023)
Published in EMBO molecular medicine (07.08.2023)
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Journal Article
The long non-coding RNA Meg3 is dispensable for hematopoietic stem cells
Sommerkamp, Pia, Renders, Simon, Ladel, Luisa, Hotz-Wagenblatt, Agnes, Schönberger, Katharina, Zeisberger, Petra, Przybylla, Adriana, Sohn, Markus, Zhou, Yunli, Klibanski, Anne, Cabezas-Wallscheid, Nina, Trumpp, Andreas
Published in Scientific reports (14.02.2019)
Published in Scientific reports (14.02.2019)
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P453: NOVEL INSIGHTS INTO MINIMAL RESIDUAL DISEASE OF ACUTE MYELOID LEUKEMIA USING PRIMARY SAMPLES AND A CLINICALLY RELEVANT PDX MODEL
Aroua, Nesrine, Karpova, Darja, Leppä, Aino‐Maija, Donato, Elisa, Przybylla, Adriana, Sohn, Markus, Zeisberger, Petra, Klein, Corinna, Döhner, Konstanze, Trumpp, Andreas
Published in HemaSphere (08.08.2023)
Published in HemaSphere (08.08.2023)
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Journal Article
PB1759: RETAINED FUNCTIONAL NORMAL AND/OR PRE‐LEUKEMIC HSCS IN THE BONE MARROW ARE ASSOCIATED TO GOOD PROGNOSIS IN DNMT3AMUTNPM1MUT AML PATIENTS
Donato, Elisa, Correia, Nadia, Andresen, Carolin, Karpova, Darja, Würth, Roberto, Klein, Corinna, Sohn, Markus, Przybylla, Adriana, Zeisberger, Petra, Rothfelder, Kathrin, Salih, Helmut, Bonig, Halvard, Stasik, Sebastian, Röllig, Christoph, Dolnik, Anna, Bullinger, Lars, Buchholz, Frank, Thiede, Christian, Hübschmann, Daniel, Trumpp, Andreas
Published in HemaSphere (08.08.2023)
Published in HemaSphere (08.08.2023)
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Journal Article
BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation
Raffel, Simon, Falcone, Mattia, Kneisel, Niclas, Hansson, Jenny, Wang, Wei, Lutz, Christoph, Bullinger, Lars, Poschet, Gernot, Nonnenmacher, Yannic, Barnert, Andrea, Bahr, Carsten, Zeisberger, Petra, Przybylla, Adriana, Sohn, Markus, Tönjes, Martje, Erez, Ayelet, Adler, Lital, Jensen, Patrizia, Scholl, Claudia, Fröhling, Stefan, Cocciardi, Sibylle, Wuchter, Patrick, Thiede, Christian, Flörcken, Anne, Westermann, Jörg, Ehninger, Gerhard, Lichter, Peter, Hiller, Karsten, Hell, Rüdiger, Herrmann, Carl, Ho, Anthony D, Krijgsveld, Jeroen, Radlwimmer, Bernhard, Trumpp, Andreas
Published in Nature (London) (16.11.2017)
Published in Nature (London) (16.11.2017)
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Journal Article
Venetoclax synergizes with gilteritinib in FLT3 wild-type high-risk acute myeloid leukemia by suppressing MCL-1
Janssen, Maike, Schmidt, Christina, Bruch, Peter-Martin, Blank, Maximilian F., Rohde, Christian, Waclawiczek, Alexander, Heid, Daniel, Renders, Simon, Göllner, Stefanie, Vierbaum, Lisa, Besenbeck, Birgit, Herbst, Sophie A., Knoll, Mareike, Kolb, Carolin, Przybylla, Adriana, Weidenauer, Katharina, Ludwig, Anne Kathrin, Fabre, Margarete, Gu, Muxin, Schlenk, Richard F., Stölzel, Friedrich, Bornhäuser, Martin, Röllig, Christoph, Platzbecker, Uwe, Baldus, Claudia, Serve, Hubert, Sauer, Tim, Raffel, Simon, Pabst, Caroline, Vassiliou, George, Vick, Binje, Jeremias, Irmela, Trumpp, Andreas, Krijgsveld, Jeroen, Müller-Tidow, Carsten, Dietrich, Sascha
Published in Blood (15.12.2022)
Published in Blood (15.12.2022)
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Frequent Whole Blood Donations Select for DNMT3A variants Mediating Enhanced Response to Erythropoietin
Karpova, Darja, Huerga Encabo, Hector, Donato, Elisa, Kotova, Iuliia, Calderazzo, Silvia, Leppä, Aino-Maija, Jasper, Panten, Przybylla, Adriana, Seifried, Erhard, Kopp-Schneider, Annette, Wong, Terrence N, Bonnet, Dominique, Bonig, Halvard, Trumpp, Andreas
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Identification of Embryonic Neural Plate Border Stem Cells and Their Generation by Direct Reprogramming from Adult Human Blood Cells
Thier, Marc Christian, Hommerding, Oliver, Panten, Jasper, Pinna, Roberta, García-González, Diego, Berger, Thomas, Wörsdörfer, Philipp, Assenov, Yassen, Scognamiglio, Roberta, Przybylla, Adriana, Kaschutnig, Paul, Becker, Lisa, Milsom, Michael D., Jauch, Anna, Utikal, Jochen, Herrmann, Carl, Monyer, Hannah, Edenhofer, Frank, Trumpp, Andreas
Published in Cell stem cell (03.01.2019)
Published in Cell stem cell (03.01.2019)
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Journal Article
Antigen presentation safeguards the integrity of the hematopoietic stem cell pool
Hernández-Malmierca, Pablo, Vonficht, Dominik, Schnell, Alexandra, Uckelmann, Hannah J., Bollhagen, Alina, Mahmoud, Mohamed A.A., Landua, Sophie-Luise, van der Salm, Elise, Trautmann, Christine L., Raffel, Simon, Grünschläger, Florian, Lutz, Raphael, Ghosh, Michael, Renders, Simon, Correia, Nádia, Donato, Elisa, Dixon, Karin O., Hirche, Christoph, Andresen, Carolin, Robens, Claudia, Werner, Paula S., Boch, Tobias, Eisel, David, Osen, Wolfram, Pilz, Franziska, Przybylla, Adriana, Klein, Corinna, Buchholz, Frank, Milsom, Michael D., Essers, Marieke A.G., Eichmüller, Stefan B., Hofmann, Wolf-Karsten, Nowak, Daniel, Hübschmann, Daniel, Hundemer, Michael, Thiede, Christian, Bullinger, Lars, Müller-Tidow, Carsten, Armstrong, Scott A., Trumpp, Andreas, Kuchroo, Vijay K., Haas, Simon
Published in Cell stem cell (05.05.2022)
Published in Cell stem cell (05.05.2022)
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Journal Article
Hematopoietic Stem Cells are Regulated by Alternative Polyadenylation
Sommerkamp, Pia, Altamura, Sandro, Ladel, Luisa, Zeisberger, Petra, Przybylla, Adriana, Cabezas-Wallscheid, Nina, Trumpp, Andreas
Published in Experimental hematology (01.08.2018)
Published in Experimental hematology (01.08.2018)
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Journal Article
Neogenin regulates hematopoietic stem cell quiescence and maintenance
Renders, Simom, Sommerkamp, Pia, Panten, Jasper, Ladel, Luisa, Przybylla, Adriana, Zeisberger, Petra, Klimmeck, Daniel, Schönberger, Katharina, Cabezas-Wallscheid, Nina, Trumpp, Andreas
Published in Experimental hematology (01.09.2017)
Published in Experimental hematology (01.09.2017)
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Journal Article
Retained functional normal and preleukemic HSCs at diagnosis are associated with good prognosis in DNMT3A mut NPM1 mut AMLs
Donato, Elisa, Correia, Nadia, Andresen, Carolin, Karpova, Darja, Würth, Roberto, Klein, Corinna, Sohn, Markus, Przybylla, Adriana, Zeisberger, Petra, Rothfelder, Kathrin, Salih, Helmut, Bonig, Halvard, Stasik, Sebastian, Röllig, Christoph, Dolnik, Anna, Bullinger, Lars, Buchholz, Frank, Thiede, Christian, Hübschmann, Daniel, Trumpp, Andreas
Published in Blood advances (28.03.2023)
Published in Blood advances (28.03.2023)
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Journal Article
Retained functional normal and preleukemic HSCs at diagnosis are associated with good prognosis in DNMT3AmutNPM1mut AMLs
Donato, Elisa, Correia, Nadia, Andresen, Carolin, Karpova, Darja, Würth, Roberto, Klein, Corinna, Sohn, Markus, Przybylla, Adriana, Zeisberger, Petra, Rothfelder, Kathrin, Salih, Helmut, Bonig, Halvard, Stasik, Sebastian, Röllig, Christoph, Dolnik, Anna, Bullinger, Lars, Buchholz, Frank, Thiede, Christian, Hübschmann, Daniel, Trumpp, Andreas
Published in Blood advances (28.03.2023)
Published in Blood advances (28.03.2023)
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Journal Article
Author Correction: BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation
Raffel, Simon, Falcone, Mattia, Kneisel, Niclas, Hansson, Jenny, Wang, Wei, Lutz, Christoph, Bullinger, Lars, Poschet, Gernot, Nonnenmacher, Yannic, Barnert, Andrea, Bahr, Carsten, Zeisberger, Petra, Przybylla, Adriana, Sohn, Markus, Tönjes, Martje, Erez, Ayelet, Adler, Lital, Jensen, Patrizia, Scholl, Claudia, Fröhling, Stefan, Cocciardi, Sibylle, Wuchter, Patrick, Thiede, Christian, Flörcken, Anne, Westermann, Jörg, Ehninger, Gerhard, Lichter, Peter, Hiller, Karsten, Hell, Rüdiger, Herrmann, Carl, Ho, Anthony D., Krijgsveld, Jeroen, Radlwimmer, Bernhard, Trumpp, Andreas
Published in Nature (London) (01.08.2018)
Published in Nature (London) (01.08.2018)
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Journal Article
BCAT1 restricts KG levels in AML stem cells leading to IDHmut-like DNA hypermethylation
Raffel, Simon, Falcone, Mattia, Kneisel, Niclas, Hansson, Jenny, Wang, Wei, Lutz, Christoph, Bullinger, Lars, Poschet, Gernot, Nonnenmacher, Yannic, Barnert, Andrea, Bahr, Carsten, Zeisberger, Petra, Przybylla, Adriana, Sohn, Markus, Tnjes, Martje, Erez, Ayelet, Adler, Lital, Jensen, Patrizia, Scholl, Claudia, Frhling, Stefan, Cocciardi, Sibylle, Wuchter, Patrick, Thiede, Christian, Flrcken, Anne, Westermann, Jrg, Ehninger, Gerhard, Lichter, Peter, Hiller, Karsten, Hell, Rdiger, Herrmann, Carl, Ho, Anthony D, Krijgsveld, Jeroen, Radlwimmer, Bernhard, Trumpp, Andreas
Published in Nature (London) (16.11.2017)
Published in Nature (London) (16.11.2017)
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