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Dye, John M, Herbert, Andrew S, Kuehne, Ana I, Barth, James F, Muhammad, Majidat A, Zak, Samantha E, Ortiz, Ramon A, Prugar, Laura I, Pratt, William D
Published in Proceedings of the National Academy of Sciences - PNAS (27.03.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (27.03.2012)
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Post-exposure immunotherapy for two ebolaviruses and Marburg virus in nonhuman primates
Brannan, Jennifer M, He, Shihua, Howell, Katie A, Prugar, Laura I, Zhu, Wenjun, Vu, Hong, Shulenin, Sergey, Kailasan, Shweta, Raina, Henna, Wong, Gary, Rahim, Md Niaz, Banadyga, Logan, Tierney, Kevin, Zhao, Xuelian, Li, Yuxing, Holtsberg, Frederick W, Dye, John M, Qiu, Xiangguo, Aman, M Javad
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Published in Nature communications (10.01.2019)
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Calcium Regulation of Hemorrhagic Fever Virus Budding: Mechanistic Implications for Host-Oriented Therapeutic Intervention
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Published in PLoS pathogens (01.10.2015)
Published in PLoS pathogens (01.10.2015)
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Venezuelan Equine Encephalitis Virus Replicon Particle Vaccine Protects Nonhuman Primates from Intramuscular and Aerosol Challenge with Ebolavirus
Herbert, Andrew S, Kuehne, Ana I, Barth, James F, Ortiz, Ramon A, Nichols, Donald K, Zak, Samantha E, Stonier, Spencer W, Muhammad, Majidat A, Bakken, Russell R, Prugar, Laura I, Olinger, Gene G, Groebner, Jennifer L, Lee, John S, Pratt, William D, Custer, Max, Kamrud, Kurt I, Smith, Jonathan F, Hart, Mary Kate, Dye, John M
Published in Journal of Virology (01.05.2013)
Published in Journal of Virology (01.05.2013)
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Synthesis and Structure–Activity Relationships of 3,5-Disubstituted-pyrrolo[2,3‑b]pyridines as Inhibitors of Adaptor-Associated Kinase 1 with Antiviral Activity
Verdonck, Sven, Pu, Szu-Yuan, Sorrell, Fiona J, Elkins, Jon M, Froeyen, Mathy, Gao, Ling-Jie, Prugar, Laura I, Dorosky, Danielle E, Brannan, Jennifer M, Barouch-Bentov, Rina, Knapp, Stefan, Dye, John M, Herdewijn, Piet, Einav, Shirit, De Jonghe, Steven
Published in Journal of medicinal chemistry (27.06.2019)
Published in Journal of medicinal chemistry (27.06.2019)
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Phosphatidylserine clustering by the Ebola virus matrix protein is a critical step in viral budding
Husby, Monica L, Amiar, Souad, Prugar, Laura I, David, Emily A, Plescia, Caroline B, Huie, Kathleen E, Brannan, Jennifer M, Dye, John M, Pienaar, Elsje, Stahelin, Robert V
Published in EMBO reports (07.11.2022)
Published in EMBO reports (07.11.2022)
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Optimization of Isothiazolo[4,3‑b]pyridine-Based Inhibitors of Cyclin G Associated Kinase (GAK) with Broad-Spectrum Antiviral Activity
Pu, Szu-Yuan, Wouters, Randy, Schor, Stanford, Rozenski, Jef, Barouch-Bentov, Rina, Prugar, Laura I, O’Brien, Cecilia M, Brannan, Jennifer M, Dye, John M, Herdewijn, Piet, De Jonghe, Steven, Einav, Shirit
Published in Journal of medicinal chemistry (26.07.2018)
Published in Journal of medicinal chemistry (26.07.2018)
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BIKE regulates dengue virus infection and is a cellular target for broad-spectrum antivirals
Pu, Szuyuan, Schor, Stanford, Karim, Marwah, Saul, Sirle, Robinson, Makeda, Kumar, Sathish, Prugar, Laura I., Dorosky, Danielle E., Brannan, Jennifer, Dye, John M., Einav, Shirit
Published in Antiviral research (01.12.2020)
Published in Antiviral research (01.12.2020)
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Interferon α/β Receptor-Deficient Mice as a Model for Ebola Virus Disease
Brannan, Jennifer M., Froude, Jeffery W., Prugar, Laura I., Bakken, Russell R., Zak, Samantha E., Daye, Sharon P., Wilheimsen, Catherine E., Dye, John M.
Published in The Journal of infectious diseases (01.10.2015)
Published in The Journal of infectious diseases (01.10.2015)
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High-Dose Mannose-Binding Lectin Therapy for Ebola Virus Infection
Michelow, Ian C., Lear, Calli, Scully, Corinne, Prugar, Laura I., Longley, Clifford B., Yantosca, L. Michael, Ji, Xin, Karpel, Marshall, Brudner, Matthew, Takahashi, Kazue, Spear, Gregory T., Ezekowitz, R. Alan B., Schmidt, Emmett V., Olinger, Gene G.
Published in The Journal of infectious diseases (15.01.2011)
Published in The Journal of infectious diseases (15.01.2011)
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Design and characterization of ebolavirus GP prehairpin intermediate mimics as drug targets
Clinton, Tracy R., Weinstock, Matthew T., Jacobsen, Michael T., Szabo‐Fresnais, Nicolas, Pandya, Maya J., Whitby, Frank G., Herbert, Andrew S., Prugar, Laura I., McKinnon, Rena, Hill, Christopher P., Welch, Brett D., Dye, John M., Eckert, Debra M., Kay, Michael S.
Published in Protein science (01.04.2015)
Published in Protein science (01.04.2015)
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Pan-filovirus monoclonal antibody cocktail protects against lethal challenge with Marburg virus in non-human primates
Prugar, Laura I., Dorosky, Danielle, Holtsberg, Frederick, Shulenin, Sergey, Vu, Hong, Howell, Katy, Bakken, Russell, Brannan, Jennifer, Dye, John M., Aman, M. Javad
Published in The Journal of immunology (1950) (01.05.2018)
Published in The Journal of immunology (1950) (01.05.2018)
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AAK1 and GAK inhibitors demonstrate activity against Filoviruses
Dorosky, Danielle, Prugar, Laura I., Pu, Szuyan, O’Brien, Cecilia, Bakken, Russell, De Jonghe, Steven, Herdewijn, Piet, Brannan, Jennifer, Dye, John M., Einav, Shirit
Published in The Journal of immunology (1950) (01.05.2018)
Published in The Journal of immunology (1950) (01.05.2018)
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Synthesis and Structure-Activity Relationships of 3,5-Disubstituted-pyrrolo2,3- bpyridines as Inhibitors of Adaptor-Associated Kinase 1 with Antiviral Activity
Verdonck, Sven, Pu, Szu-Yuan, Sorrell, Fiona J, Elkins, Jon M, Froeyen, Mathy, Gao, Ling-Jie, Prugar, Laura I, Dorosky, Danielle E, Brannan, Jennifer M, Barouch-Bentov, Rina, Knapp, Stefan, Dye, John M, Herdewijn, Piet, Einav, Shirit, De Jonghe, Steven
Published in Journal of medicinal chemistry (27.06.2019)
Published in Journal of medicinal chemistry (27.06.2019)
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Small-molecule probe targeting viral PPxY L-domain inhibits filovirus and arenavirus egress
Prugar, Laura I, Dye, John M, Loughran, Marie, Wrobel, Jay E, Reitz, Allen B, Freedman, Bruce D, Harty, Ronald N, Herbert, Andrew S
Published in The Journal of immunology (1950) (01.05.2016)
Published in The Journal of immunology (1950) (01.05.2016)
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Calcium Regulation of Hemorrhagic Fever Virus Budding: Mechanistic Implications for Host-Oriented Therapeutic Intervention: e1005220
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Published in PLoS pathogens (01.10.2015)
Published in PLoS pathogens (01.10.2015)
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The Ebola virus matrix protein clusters phosphatidylserine, a critical step in viral budding
Husby, Monica L, Amiar, Souad, Prugar, Laura I, David, Emily A, Plescia, Caroline B, Huie, Kathleen E, Brannan, Jennifer M, Dye, John M, Pienaar, Elsje, Stahelin, Robert V
Published in bioRxiv (14.03.2022)
Published in bioRxiv (14.03.2022)
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