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VEGF synthesis is induced by prostacyclin and TGF‐β in distal lung fibroblasts from COPD patients and control subjects: Implications for pulmonary vascular remodelling
Westergren‐Thorsson, Gunilla, Bagher, Mariam, Andersson‐Sjöland, Annika, Thiman, Lena, Löfdahl, Claes‐Göran, Hallgren, Oskar, Bjermer, Leif, Larsson‐Callerfelt, Anna‐Karin
Published in Respirology (Carlton, Vic.) (01.01.2018)
Published in Respirology (Carlton, Vic.) (01.01.2018)
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Mannitol triggers mast cell–dependent contractions of human small bronchi and prostacyclin bronchoprotection
Säfholm, Jesper, Manson, Martijn L., Bood, Johan, Al-Ameri, Mamdoh, Orre, Ann-Charlotte, Raud, Johan, Dahlén, Sven-Erik, Adner, Mikael
Published in Journal of allergy and clinical immunology (01.10.2019)
Published in Journal of allergy and clinical immunology (01.10.2019)
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Comparative Effects of Metamizole (Dipyrone) and Naproxen on Renal Function and Prostacyclin Synthesis in Salt-Depleted Healthy Subjects - A Randomized Controlled Parallel Group Study
Blaser, Lea S, Duthaler, Urs, Bouitbir, Jamal, Leuppi-Taegtmeyer, Anne B, Liakoni, Evangelia, Dolf, Reto, Mayr, Michael, Drewe, Jürgen, Krähenbühl, Stephan, Haschke, Manuel
Published in Frontiers in pharmacology (07.09.2021)
Published in Frontiers in pharmacology (07.09.2021)
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Pharmacokinetics of the novel oral prostacyclin receptor agonist selexipag in subjects with hepatic or renal impairment
Kaufmann, Priska, Cruz, Hans G., Krause, Andreas, Ulč, Ivan, Halabi, Atef, Dingemanse, Jasper
Published in British journal of clinical pharmacology (01.08.2016)
Published in British journal of clinical pharmacology (01.08.2016)
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SAT0315 INHIBITION OF MICROSOMAL PROSTAGLANDIN E SYNTHASE-1 (MPGES-1) BY GS-248 REDUCES PROSTAGLANDIN E2 BIOSYNTHESIS WHILE INCREASING PROSTACYCLIN IN HUMAN SUBJECTS
Edenius, C., Ekström, G., Kolmert, J., Morgenstern, R., Stenberg, P., Jakobsson, P. J., Tornling, G.
Published in Annals of the rheumatic diseases (01.06.2020)
Published in Annals of the rheumatic diseases (01.06.2020)
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Effect of lopinavir/ritonavir on the pharmacokinetics of selexipag an oral prostacyclin receptor agonist and its active metabolite in healthy subjects
Kaufmann, Priska, Niglis, Séverine, Bruderer, Shirin, Segrestaa, Jérôme, Äänismaa, Päivi, Halabi, Atef, Dingemanse, Jasper
Published in British journal of clinical pharmacology (01.10.2015)
Published in British journal of clinical pharmacology (01.10.2015)
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Prostacyclin (epoprostenol) induces headache in healthy subjects
Wienecke, Troels, Olesen, Jes, Oturai, Peter S., Ashina, Messoud
Published in Pain (Amsterdam) (30.09.2008)
Published in Pain (Amsterdam) (30.09.2008)
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The Prostacyclin Analogue Iloprost Modulates CXCL10 in Systemic Sclerosis
Colasanti, Tania, Stefanantoni, Katia, Fantini, Cristina, Corinaldesi, Clarissa, Vasile, Massimiliano, Marampon, Francesco, Di Luigi, Luigi, Antinozzi, Cristina, Sgrò, Paolo, Lenzi, Andrea, Riccieri, Valeria, Crescioli, Clara
Published in International journal of molecular sciences (05.09.2022)
Published in International journal of molecular sciences (05.09.2022)
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Cyclooxygenase-1 and -2–Dependent Prostacyclin Formation in Patients With Atherosclerosis
Belton, Orina, Byrne, Dara, Kearney, Dermot, Leahy, Austin, Fitzgerald, Desmond J.
Published in Circulation (New York, N.Y.) (22.08.2000)
Published in Circulation (New York, N.Y.) (22.08.2000)
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Multiple-Dose Up-Titration Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Selexipag, an Orally Available Selective Prostacyclin Receptor Agonist, in Healthy Subjects
Bruderer, Shirin, Hurst, Noémie, Kaufmann, Priska, Dingemanse, Jasper
Published in Pharmacology (01.01.2014)
Published in Pharmacology (01.01.2014)
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Effect of Gemfibrozil on The Pharmacokinetics of Selexipag, An oral Prostacyclin Receptor Agonist, And Its Active Metabolite In Healthy Male Subjects
Bruderer, S., Petersen-Sylla, M., Boehler, M., Remeňová, T., Halabi, A., Dingemanse, J.
Published in Clinical therapeutics (01.08.2017)
Published in Clinical therapeutics (01.08.2017)
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Effect of Rifampicin on The Pharmacokinetics of Selexipag, An Oral Prostacyclin Receptor Agonist, and Its Active Metabolite In Healthy Male Subjects
Bruderer, S., Petersen-Sylla, M., Boehler, M., Remeňová, T., Halabi, A., Dingemanse, J.
Published in Clinical therapeutics (01.08.2017)
Published in Clinical therapeutics (01.08.2017)
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Selexipag: An Oral and Selective IP Prostacyclin Receptor Agonist for the Treatment of Pulmonary Arterial Hypertension
Asaki, Tetsuo, Kuwano, Keiichi, Morrison, Keith, Gatfield, John, Hamamoto, Taisuke, Clozel, Martine
Published in Journal of medicinal chemistry (24.09.2015)
Published in Journal of medicinal chemistry (24.09.2015)
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Inhaled Prostacyclin on Exercise Echocardiographic Cardiac Function in Preserved Ejection Fraction Heart Failure
Huang, Chen-Yu, Lee, Jen-Kuang, Chen, Zheng-Wei, Cheng, Jen-Fang, Chen, Ssu-Yuan, Lin, Lian-Yu, Wu, Cho-Kai
Published in Medicine and science in sports and exercise (01.02.2020)
Published in Medicine and science in sports and exercise (01.02.2020)
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Pharmacokinetics and Tolerability of the Novel Oral Prostacyclin IP Receptor Agonist Selexipag
Kaufmann, Priska, Okubo, Kaori, Bruderer, Shirin, Mant, Tim, Yamada, Tetsuhiro, Dingemanse, Jasper, Mukai, Hideya
Published in American Journal of Cardiovascular Drugs (01.06.2015)
Published in American Journal of Cardiovascular Drugs (01.06.2015)
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Induction of Prostacyclin by Steady Laminar Shear Stress Suppresses Tumor Necrosis Factor-α Biosynthesis via Heme Oxygenase-1 in Human Endothelial Cells
Di Francesco, Luigia, Totani, Licia, Dovizio, Melania, Piccoli, Antonio, Di Francesco, Andrea, Salvatore, Tania, Pandolfi, Assunta, Evangelista, Virgilio, Dercho, Ryan A., Seta, Francesca, Patrignani, Paola
Published in Circulation research (27.02.2009)
Published in Circulation research (27.02.2009)
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VEGF synthesis is induced by prostacyclin and TGF ‐β in distal lung fibroblasts from COPD patients and control subjects: I mplications for pulmonary vascular remodelling
Westergren‐Thorsson, Gunilla, Bagher, Mariam, Andersson‐Sjöland, Annika, Thiman, Lena, Löfdahl, Claes‐Göran, Hallgren, Oskar, Bjermer, Leif, Larsson‐Callerfelt, Anna‐Karin
Published in Respirology (Carlton, Vic.) (01.01.2018)
Published in Respirology (Carlton, Vic.) (01.01.2018)
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