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Low-Density Lipoprotein Cholesterol Lowering With Evolocumab and Outcomes in Patients With Peripheral Artery Disease: Insights From the FOURIER Trial (Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk)
Bonaca, Marc P., Nault, Patrice, Giugliano, Robert P., Keech, Anthony C., Pineda, Armando Lira, Kanevsky, Estella, Kuder, Julia, Murphy, Sabina A., Jukema, J. Wouter, Lewis, Basil S., Tokgozoglu, Lale, Somaratne, Ransi, Sever, Peter S., Pedersen, Terje R., Sabatine, Marc S.
Published in Circulation (New York, N.Y.) (23.01.2018)
Published in Circulation (New York, N.Y.) (23.01.2018)
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Predicting Benefit From Evolocumab Therapy in Patients With Atherosclerotic Disease Using a Genetic Risk Score: Results From the FOURIER Trial
Marston, Nicholas A., Kamanu, Frederick K., Nordio, Francesco, Gurmu, Yared, Roselli, Carolina, Sever, Peter S., Pedersen, Terje R., Keech, Anthony C., Wang, Huei, Lira Pineda, Armando, Giugliano, Robert P., Lubitz, Steven A., Ellinor, Patrick T., Sabatine, Marc S., Ruff, Christian T.
Published in Circulation (New York, N.Y.) (25.02.2020)
Published in Circulation (New York, N.Y.) (25.02.2020)
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Comprehensive characterization of protein–protein interactions perturbed by disease mutations
Cheng, Feixiong, Zhao, Junfei, Wang, Yang, Lu, Weiqiang, Liu, Zehui, Zhou, Yadi, Martin, William R., Wang, Ruisheng, Huang, Jin, Hao, Tong, Yue, Hong, Ma, Jing, Hou, Yuan, Castrillon, Jessica A., Fang, Jiansong, Lathia, Justin D., Keri, Ruth A., Lightstone, Felice C., Antman, Elliott Marshall, Rabadan, Raul, Hill, David E., Eng, Charis, Vidal, Marc, Loscalzo, Joseph
Published in Nature genetics (01.03.2021)
Published in Nature genetics (01.03.2021)
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Efficacy and Safety of Evolocumab in Chronic Kidney Disease in the FOURIER Trial
Charytan, David M., Sabatine, Marc S., Pedersen, Terje R., Im, KyungAh, Park, Jeong-Gun, Pineda, Armando Lira, Wasserman, Scott M., Deedwania, Prakash, Olsson, Anders G., Sever, Peter S., Keech, Anthony C., Giugliano, Robert P.
Published in Journal of the American College of Cardiology (18.06.2019)
Published in Journal of the American College of Cardiology (18.06.2019)
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Thyroid stimulating hormone exhibits the impact on LDLR/LDL-c via up-regulating hepatic PCSK9 expression
Gong, Yingyun, Ma, Yizhe, Ye, Zhengqin, Fu, Zhenzhen, Yang, Panpan, Gao, Beibei, Guo, Wen, Hu, Dandan, Ye, Jingya, Ma, Shuai, Zhang, Fan, Zhou, Li, Xu, Xinyu, Li, Zhong, Yang, Tao, Zhou, Hongwen
Published in Metabolism, clinical and experimental (01.11.2017)
Published in Metabolism, clinical and experimental (01.11.2017)
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May statins and PCSK9 inhibitors be protective from COVID-19 in familial hypercholesterolemia subjects?
Scicali, Roberto, Di Pino, Antonino, Piro, Salvatore, Rabuazzo, Agata M., Purrello, Francesco
Published in Nutrition, metabolism, and cardiovascular diseases (25.06.2020)
Published in Nutrition, metabolism, and cardiovascular diseases (25.06.2020)
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The interplay of LDLR, PCSK9, and lncRNA- LASER genes expression in coronary artery disease: Implications for therapeutic interventions
Ghiasvand, Tayebe, Karimi, Jamshid, Khodadadi, Iraj, Yazdi, Amirhossein, Khazaei, Salman, kichi, Zahra Abedi, Hosseini, Seyed Kianoosh
Published in Prostaglandins & other lipid mediators (01.03.2025)
Published in Prostaglandins & other lipid mediators (01.03.2025)
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PCSK9 Association With Lipoprotein(a)
Tavori, Hagai, Christian, Devon, Minnier, Jessica, Plubell, Deanna, Shapiro, Michael D., Yeang, Calvin, Giunzioni, Ilaria, Croyal, Mikael, Duell, P. Barton, Lambert, Gilles, Tsimikas, Sotirios, Fazio, Sergio
Published in Circulation research (24.06.2016)
Published in Circulation research (24.06.2016)
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Long-Term Evolocumab in Patients With Established Atherosclerotic Cardiovascular Disease
O'Donoghue, Michelle L., Giugliano, Robert P., Wiviott, Stephen D., Atar, Dan, Keech, Anthony, Kuder, Julia F., Im, KyungAh, Murphy, Sabina A., Flores-Arredondo, Jose H., López, J. Antonio G., Elliott-Davey, Mary, Wang, Bei, Monsalvo, Maria Laura, Abbasi, Siddique, Sabatine, Marc S.
Published in Circulation (New York, N.Y.) (11.10.2022)
Published in Circulation (New York, N.Y.) (11.10.2022)
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Stroke Prevention With the PCSK9 (Proprotein Convertase Subtilisin-Kexin Type 9) Inhibitor Evolocumab Added to Statin in High-Risk Patients With Stable Atherosclerosis
Giugliano, Robert P., Pedersen, Terje R., Saver, Jeffrey L., Sever, Peter S., Keech, Anthony C., Bohula, Erin A., Murphy, Sabina A., Wasserman, Scott M., Honarpour, Narimon, Wang, Huei, Lira Pineda, Armando, Sabatine, Marc S.
Published in Stroke (1970) (01.05.2020)
Published in Stroke (1970) (01.05.2020)
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Clinical impact of PCSK9 inhibitor on stabilization and regression of lipid-rich coronary plaques: a near-infrared spectroscopy study
Ota, Hideaki, Omori, Hiroyuki, Kawasaki, Masanori, Hirakawa, Akihiro, Matsuo, Hitoshi
Published in European heart journal cardiovascular imaging (24.01.2022)
Published in European heart journal cardiovascular imaging (24.01.2022)
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Association Between Achieved Low-Density Lipoprotein Cholesterol Levels and Long-Term Cardiovascular and Safety Outcomes: An Analysis of FOURIER-OLE
Gaba, Prakriti, O’Donoghue, Michelle L., Park, Jeong-Gun, Wiviott, Stephen D., Atar, Dan, Kuder, Julia F., Im, KyungAh, Murphy, Sabina A., De Ferrari, Gaetano M., Gaciong, Zbigniew A., Toth, Kalman, Gouni-Berthold, Ioanna, Lopez-Miranda, Jose, Schiele, François, Mach, François, Flores-Arredondo, Jose H., López, J. Antonio G., Elliott-Davey, Mary, Wang, Bei, Monsalvo, Maria Laura, Abbasi, Siddique, Giugliano, Robert P., Sabatine, Marc S.
Published in Circulation (New York, N.Y.) (18.04.2023)
Published in Circulation (New York, N.Y.) (18.04.2023)
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American Association of Clinical Endocrinologists and American College of Endocrinology Guidelines for Management of Dyslipidemia and Prevention of Cardiovascular Disease
Jellinger, Paul S., Handelsman, Yehuda, Rosenblit, Paul D., Bloomgarden, Zachary T., Fonseca, Vivian A., Garber, Alan J., Grunberger, George, Guerin, Chris K., Bell, David S.H., Mechanick, Jeffrey I., Pessah-Pollack, Rachel, Wyne, Kathleen, Smith, Donald, Brinton, Eliot A., Fazio, Sergio, Davidson, Michael, Davidson, Michael H., Smith, Donald A., Bush, Michael, Zangeneh, Farhad
Published in Endocrine practice (01.04.2017)
Published in Endocrine practice (01.04.2017)
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PCSK9 deficiency rewires heart metabolism and drives heart failure with preserved ejection fraction
Da Dalt, Lorenzo, Castiglioni, Laura, Baragetti, Andrea, Audano, Matteo, Svecla, Monika, Bonacina, Fabrizia, Pedretti, Silvia, Uboldi, Patrizia, Benzoni, Patrizia, Giannetti, Federica, Barbuti, Andrea, Pellegatta, Fabio, Indino, Serena, Donetti, Elena, Sironi, Luigi, Mitro, Nico, Catapano, Alberico Luigi, Norata, Giuseppe Danilo
Published in European heart journal (21.08.2021)
Published in European heart journal (21.08.2021)
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PCSK9 deficiency results in increased ectopic fat accumulation in experimental models and in humans
Baragetti, Andrea, Balzarotti, Gloria, Grigore, Liliana, Pellegatta, Fabio, Guerrini, Uliano, Pisano, Giuseppina, Fracanzani, Anna L, Fargion, Silvia, Norata, Giuseppe D, Catapano, Alberico L
Published in European journal of preventive cardiology (01.11.2017)
Published in European journal of preventive cardiology (01.11.2017)
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PCSK9 Activity Is Potentiated Through HDL Binding
Burnap, Sean A., Sattler, Katherine, Pechlaner, Raimund, Duregotti, Elisa, Lu, Ruifang, Theofilatos, Konstantinos, Takov, Kaloyan, Heusch, Gerd, Tsimikas, Sotirios, Fernández-Hernando, Carlos, Berry, Sarah E., Hall, Wendy L., Notdurfter, Marlene, Rungger, Gregorio, Paulweber, Bernhard, Willeit, Johann, Kiechl, Stefan, Levkau, Bodo, Mayr, Manuel
Published in Circulation research (12.11.2021)
Published in Circulation research (12.11.2021)
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Enhanced identification of familial hypercholesterolemia using central laboratory algorithms
Ibrahim, Shirin, Nurmohamed, Nick S., Nierman, Melchior C., de Goeij, Jim N., Zuurbier, Linda, van Rooij, Jeroen, Schonck, Willemijn A.M., de Vries, Jard, Hovingh, G. Kees, Reeskamp, Laurens F., Stroes, Erik S.G.
Published in Atherosclerosis (01.06.2024)
Published in Atherosclerosis (01.06.2024)
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Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia
Khera, Amit V., Won, Hong-Hee, Peloso, Gina M., Lawson, Kim S., Bartz, Traci M., Deng, Xuan, van Leeuwen, Elisabeth M., Natarajan, Pradeep, Emdin, Connor A., Bick, Alexander G., Morrison, Alanna C., Brody, Jennifer A., Gupta, Namrata, Nomura, Akihiro, Kessler, Thorsten, Duga, Stefano, Bis, Joshua C., van Duijn, Cornelia M., Cupples, L. Adrienne, Psaty, Bruce, Rader, Daniel J., Danesh, John, Schunkert, Heribert, McPherson, Ruth, Farrall, Martin, Watkins, Hugh, Lander, Eric, Wilson, James G., Correa, Adolfo, Boerwinkle, Eric, Merlini, Piera Angelica, Ardissino, Diego, Saleheen, Danish, Gabriel, Stacey, Kathiresan, Sekar
Published in Journal of the American College of Cardiology (07.06.2016)
Published in Journal of the American College of Cardiology (07.06.2016)
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Serum Levels of PCSK9 Are Increased in Patients With Active Ulcerative Colitis Representing a Potential Biomarker of Disease Activity: A Cross-sectional Study
Marinelli, Carla, Zingone, Fabiana, Lupo, Maria Giovanna, Marin, Raffaella, D'Incà, Renata, Gubbiotti, Alessandro, Massimi, Davide, Casadei, Cesare, Barberio, Brigida, Ferri, Nicola, Savarino, Edoardo
Published in Journal of clinical gastroenterology (01.10.2022)
Published in Journal of clinical gastroenterology (01.10.2022)
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